ULTRASONIC REFLEX TRANSMISSION IMAGING

超声波反射透射成像

• 批准号: 3182230
• 负责人: PHILIP S GREEN
• 金额: $ 25.89万
• 依托单位: SRI INTERNATIONAL
• 依托单位国家: 美国
• 财政年份: 1985
• 资助国家: 美国
• 起止时间: 1985-12-01 至 1992-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3182230
• 关键词: clinical biomedical equipment; image processing

This application is for the continuation of research and development of reflex transmission imaging (RTI), a method for producing orthographic images of tissue attenuation using augmented B-scan technology. Unlike other methods for producing orthographic transmission images, which usually require water immersion, RT images can be made with a single B- scan-size transducer. Conventional B-scan and RTI are totally compatible. RTI provides supplementary information to the diagnostician- -a second viewing perspective and sensitivity to tissue attenuation. RTI should find application in the evaluation of many medical conditions. During the preceding grant period we have established the feasibility of this method, made major improvements to it, completed one instrument that is now ready for clinical evaluation and begun conversion to RTI of a second instrument. Our laboratory experimens demonstrated the potential of RTI for imaging kidney stones. We have now licensed RTI for use with lithotripsy only. During the proposed continuation we will conduct additional basic studies to improve the effectiveness and expand the applicability of RTI. These studies will include optimization of the method we have developed for reducing the effects of backscatterer inhomogeneity on the image. We will develop improved methods of image display and, using cadaver organs, investigate the applicability of RTI to a wider range of organs and pathologies. We will complete, in two stages, the conversion to RTI of a new Diasonics SPA-400 annular array imaging system. This system was given to SRI for use on this grant by SRI's lithotripsy licensee, without commercial obligation beyond lithotripsy applications. Using this instrument, the diagnostic applications of RTI will be explored at the University of California Medical School. A peripheral-organ RTI system, recently completed under this grant, will be clinically evaluated at the Palo Alto Medical Foundation clinic, with special emphasis on its potential application to the breast. We will develop a second generation RTI system that produces real-time RT images (the current instruments require 1 to 15 seconds to make an RT image, although their B-scans are realtime). This will involve two- dimensional transducer array technology and parallel processing.

该应用是为了延续研究和开发 反射传输成像（RTI），一种产生拼字法的方法 使用增强B扫描技术的组织衰减图像。 与众不同 产生拼字传输图像的其他方法，该图像 通常需要浸入水，可以用单个b-制作RT图像 扫描大小的传感器。 传统的B扫描和RTI完全 兼容的。 RTI向诊断医生提供补充信息 - - 第二观看透视和对组织衰减的敏感性。 RTI 应该在评估许多医疗状况中找到应用。 在上一个赠款期间，我们确定了 这种方法对它进行了重大改进，完成了一种工具 现在准备进行临床评估，并开始转换为A的RTI 第二个乐器。 我们的实验室实验证明了潜力 用于成像肾结石的RTI。 我们现在已获得许可的RTI供 仅岩石疗法。 在拟议的延续期间，我们将进行其他基础研究 提高有效性并扩大RTI的适用性。 这些 研究将包括优化我们为 减少反向散射器不均匀性对图像的影响。 我们 将开发改进的图像显示方法，并使用尸体器官， 调查RTI对更广泛的器官的适用性， 病理。 我们将在两个阶段完成转换为RTI 新的Diasonics SPA-400环形阵列成像系统。 这个系统是 SRI的碎石摄影者授予SRI供SRI使用，没有 超越碎石疗法的商业义务。 使用此 仪器，将探索RTI的诊断应用 加利福尼亚大学医学院。 外围和器官RTI系统， 最近根据该赠款完成的，将在临床上进行临床评估 帕洛阿尔托医学基金会诊所，特别强调 潜在的乳房应用。 我们将开发一个生产实时RT的第二代RTI系统 图像（当前的仪器需要1到15秒才能制作RT 图像，尽管他们的B扫描是实时的）。 这将涉及两个 尺寸传感器阵列技术和并行处理。