A novel multiscale model to investigate mechanical properties of cartilage

研究软骨力学性能的新型多尺度模型

• 批准号: DP180103009
• 负责人: Prof Yuantong Gu
• 金额: $ 27.49万
• 依托单位: Queensland University of Technology
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-06-12 至 2021-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180103009
• 关键词: novel; multiscale; model; investigate; mechanical

This project aims to develop a new multiscale model to investigate anisotropic and inhomogeneous mechanical properties of cartilage. It has been found that the mechanical properties of cartilage highly depend on its microstructures and components. The new model is proposed based on a new constitutive relation in the macroscale and a novel algorithm to obtain local stress distributions in the microscale as well as through rigorous experimental validations. This model will be a powerful tool to understand cartilage mechanical properties. It will accelerate the design of mechanically viable artificial cartilage biomaterial, which will provide significant economic benefits and place Australia in the forefront of modelling and biomaterials.

该项目旨在开发一种新的多尺度模型来研究软骨的各向异性和不均匀机械特性。研究发现，软骨的机械性能很大程度上取决于其微观结构和成分。该新模型是基于宏观尺度上的新本构关系和微观尺度上获得局部应力分布的新算法并经过严格的实验验证而提出的。 该模型将成为了解软骨力学特性的有力工具。它将加速机械上可行的人造软骨生物材料的设计，这将带来显着的经济效益，并使澳大利亚处于建模和生物材料领域的前沿。