AGE-RELATED EYE DISEASE STUDY

年龄相关眼病研究

• 批准号: 6086130
• 负责人: THOMAS R FRIBERG
• 金额: $ 0.97万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-03-01 至 2000-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6086130
• 关键词: cataract; clinical trials; diet therapy; dietary trace element; disease /disorder proneness /risk; human middle age (35-64); human subject; human therapy evaluation; macular degeneration; macular drusen; nutrition related tag; pathology; tocopherols; zinc

The purpose of this study, the Aged RElated Eye Disease Study (AREDS), is to enroll patients with minor to severe drusen pathology and a) follow the natural progression of macular degeneration; and b) determine if dietary supplements of multivitamins, mineral(s) or multivitamins and minerals delay the progression of the disease. Because patients enrolled will not have optically significant lens opacities, this study will also provide information on development of cataracts in individuals with macular disease. The study will provide new information regarding the progression of macular degeneration and risk factors for cataract formation. Moreover, the effects of dietary supplements in the progression of macular disease and cataract formation will be assessed. The prospective nature of this study, its focus on the progression of drusen pathology, and its evaluation of the effects of dietary supplements make this a unique and much needed study.

这项研究（老年相关眼病研究 (AREDS)）的目的是 招募患有轻度至重度玻璃疣病理的患者，并且 a) 遵循 黄斑变性的自然进展； b) 确定饮食是否 多种维生素、矿物质或多种维生素和矿物质的补充剂 延缓疾病的进展。 因为入组的患者不会 具有光学显着的晶状体混浊，这项研究还将提供 有关黄斑患者发生白内障的信息 疾病。 该研究将提供有关进展的新信息 黄斑变性和白内障形成的危险因素。 而且， 膳食补充剂对黄斑疾病进展的影响 并将评估白内障的形成。 这件事的前瞻性 研究、其重点关注玻璃疣病理进展及其评估 膳食补充剂的作用使其成为独特且急需的 学习。