SKIN CANCER PREVENTION IN A PEDIATRIC POPULATION

儿童皮肤癌的预防

• 批准号: 2769945
• 负责人: LORI A. CRANE
• 金额: $ 15.85万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-15 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2769945
• 关键词: adult human (21+); behavioral /social science research tag; cancer prevention; cancer risk; clinical research; clinical trials; health care service evaluation; human subject; infant human (0-1 year); melanoma; mother /infant health care; pediatric neoplasm /cancer; pediatrics; preschool child (1-5)

DESCRIPTION (Applicant's Description) Total lifetime sun exposure and intermittent intense exposure to the sun are the primary preventable risk factors for skin cancer, including malignant melanoma. Up to 80 percent of lifetime sun exposure is estimated to occur prior to age 18, and a single severe sunburn in childhood can double the risk of melanoma. Prevention of over-exposure to the sun, beginning at birth, has the greatest long-term potential for reversing the rising incidence of melanoma and non-melanoma skin cancer. The proposed study translates basic epidemiologic research on skin cancer and melanoma to a behavioral intervention aimed at reducing sun exposure in a cohort of newborns. In this randomized controlled trial, medical offices of an HMO will be randomly assigned to intervention or control. Pediatric care providers at intervention sites will deliver brief informational messages and resources for sun protection to parents of infants at well-child visits between age 2 and 36 months. Research in smoking cessation and screening mammography suggests that the physician messages will be a powerful promoter of behavior change. Annual interviews and skin exams will measure differences between intervention and control subjects in knowledge, attitudes and practices related to sun exposure, as well as differences in signs of sun exposure such as mole acquisition, sunburns, and tanning. Process evaluation, using provider surveys and exit interviews of parents, will determine the extent to which the intervention was delivered by providers. This study has the potential of discovering a important method of reducing skin cancer risk. In addition, it will extend knowledge regarding the impact of provider-delivered health promotion advice, and may identify a method for changing parents' behavior that could be translated to other health practices, such as diet and exercise.

描述（申请人的描述）终生暴露的总阳光和 间歇性地暴露于太阳是可预防的风险 皮肤癌的因素，包括恶性黑色素瘤。 多达80％ 终生的阳光暴露估计发生在18岁之前，一个 童年时期的严重晒伤会使黑色素瘤的风险增加一倍。 预防 从出生时开始过度暴露于太阳，长期最大 逆转黑色素瘤和非黑色素瘤发病率上升的潜力 皮肤癌。 拟议的研究翻译了有关皮肤癌的基本流行病学研究 和黑色素瘤进行行为干预措施，以减少阳光暴露 一群新生儿。 在这个随机对照试验中，医疗办公室 HMO将随机分配给干预或控制。 小儿 干预网站的护理提供者将提供简短的信息 向婴儿父母提供防晒的消息和资源 儿童访问2至36个月之间。 吸烟研究 停止和筛查乳房X线摄影表明医师信息 将是行为改变的强大促进者。 年度面试和皮肤 考试将衡量干预和控制对象之间的差异 知识，态度和实践与暴露有关 阳光暴露的迹象差异，例如获取痣，晒伤和 晒黑。 过程评估，使用提供商调查和退出访谈 父母将确定干预的程度 由提供者。 这项研究的潜力是发现一种重要的减少方法 皮肤癌风险。 此外，它将扩展有关 提供者提供的健康促进建议的影响，并可能确定 改变父母行为的方法，可以转化为其他 健康实践，例如饮食和运动。