ON AIRWAY ANESTHETIC GAS ANALYZER

气道麻醉气体分析仪

基本信息

批准号：
2546163
负责人：
MICHAEL J O'CALLAGHAN
金额：
$ 35.73万
依托单位：
DISPLAYTECH, INC.
依托单位国家：
美国
项目类别：
财政年份：
1994
资助国家：
美国
起止时间：
1994-09-30 至 1999-09-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/2546163
关键词：
biomedical equipment development electron optics environmental health infrared radiation liquid crystal optical polarization patient monitoring device respiratory gas analyzer respiratory gas level

项目摘要

Our aim is to develop an on-airway anesthetic gas analyzer capable of identifying and quantifying the five most common anesthetic agents used in surgical procedures. Since it is mounted on the patient airway and has a rapid response time, the proposed instrument is also capable of breath by breath measurement of inspired and expired anesthetic agents. The five most common anesthetic agents, desflurane, enflurane, halothane, isoflurane and sevoflurane, each have unique absorption bands in the 8-13 micromole Mid-IR region. Current anesthetic gas analyzers require a mechanical chopper because Mid-IR detectors are sensitive to the change in optical power rather than absolute power. Mechanical choppers give too much vibration, and make them too large and heavy to mount on the patient airway. We propose to develop a compact, light, inexpensive, electro- optic, 8-13 micromole chopper (non-mechanical, no moving parts, no vibration) using ferroelectric liquid crystal (FLC) technology and an innovative manufacturing method for producing low cost IR polarizers. The device will differentiate between anesthetics for increased patient safety. In addition to medical applications this shutter will also be incorporated in spectrometers for environmental monitoring, industrial monitoring, astronomy and automobile emissions testing. PROPOSED COMMERCIAL APPLICATIONS: Anesthetic monitors, emissions testing

我们的目标是开发一种气道麻醉气体分析仪，能够识别和量化五种最常用的麻醉剂在外科手术中。由于它安装在患者气道上并且具有响应时间快，建议的仪器也能呼吸通过吸入和呼出麻醉剂的呼吸测量。五个最常见的麻醉剂，地氟烷，安氟烷，氟烷，异氟烷和七氟烷在 8-13 范围内各有独特的吸收带微摩尔中红外区域。目前的麻醉气体分析仪需要机械斩波器，因为中红外探测器对变化敏感是光功率而不是绝对功率。机械斩波器也给振动太大，导致它们太大太重而无法安装在患者身上呼吸道。我们建议开发一种紧凑、轻便、廉价的电动光学，8-13 微摩尔斩波器（非机械，无活动部件，无振动）使用铁电液晶（FLC）技术和用于生产低成本红外偏振片的创新制造方法。这设备将区分麻醉剂，以增加病人的使用率安全。除了医疗应用之外，该快门还可用于纳入环境监测、工业光谱仪监测、天文学和汽车排放测试。拟议的商业应用：麻醉监视器、排放测试