Core A: Administrative and Enrollment Core

核心 A：行政和招生核心

基本信息

批准号：
10555690
负责人：
LI-SAN WANG
金额：
$ 517.14万
依托单位：
UNIVERSITY OF PENNSYLVANIA
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-07-01 至 2028-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10555690
关键词：
Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Asian Asian Americans Benchmarking Biological Markers Budgets Canada Collaborations Communities Complex Consent Forms Data Data Analyses Data Set Dementia Development Electronic Mail Enrollment Ensure FAIR principles Freezing Funding Agency Future Genetic Genetic Diseases Genetic study Genotype Human Subject Research Institutional Review Boards Leadership National Institute on Aging Participant Performance Persons Phenotype Progress Reports Protocols documentation Publications Qualifying Recruitment Activity Recurrence Research Research Personnel Research Project Grants Resources SNP array Sampling Schedule Science Site Standardization Structure Training Training Activity Transfer Agreement Update Work cohort data access data exchange data harmonization data management data sharing dementia risk functional genomics genome sequencing genome wide association study genome-wide genomic data interest meetings non-genetic outreach phenotypic data programs quality assurance recruit repository response symposium web site whole genome

项目摘要

Administrative and Enrollment Core (Core A) Abstract The Administrative and Enrollment Core (Core A) is mandated by the PAR and will oversee, facilitate and coordinate all ACAD activities carried out by other Cores and Projects. Using a robust administrative structure, the Core directs the ACAD’s activities to ensure maximal coordination and produce cutting-edge science to support the ACAD project. Core A will identify relevant ADRD data sets (ADGC, ADSP and non-ADSP data), and coordinate acquisition, processing, and harmonization of these data with the Data Management and Analysis Core (Core D) and Projects. Data will include: 1) genetic data (GWAS SNP array data), 2) biomarker and functional genomics (FG) data, and 3) phenotype data from ACAD participants and other non-ACAD datasets. Core A will coordinate transfer of ACAD data and analysis results to National Institute on Aging Genetics of Alzheimer’s Disease Storage site (NIAGADS) for sharing with the general scientific community.

行政和招生核心（核心 A）摘要行政和招生核心（核心 A）由 PAR 授权，将监督、促进和使用强大的管理结构协调其他核心和项目开展的所有 ACAD 活动，核心指导 ACAD 的活动，以确保最大程度的协调并产生尖端科学，以支持 ACAD 项目。核心 A 将识别相关 ADRD 数据集（ADGC、ADSP 和非 ADSP 数据），并与数据管理和协调这些数据的获取、处理和协调分析核心（核心 D）和项目数据将包括：1) 遗传数据（GWAS SNP 阵列数据），2) 生物标志物。和功能基因组学 (FG) 数据，以及 3) 来自 ACAD 参与者和其他非 ACAD 的表型数据核心 A 将协调 ACAD 数据和分析结果向国家老龄化研究所的传输。阿尔茨海默氏病遗传学存储站点 (NIAGADS)，用于与一般科学界共享。