ACORN: BioCore

橡子：生物核心

基本信息

批准号：
10526255
负责人：
BENITA L. MCVICKER
金额：
$ 32.62万
依托单位：
UNIVERSITY OF NEBRASKA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-02-28 至 2028-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10526255
关键词：
Age Alcohol consumption Alcohols Animal Model Animals Archives Behavior Biological Markers Biological Models Cell model Cells Characteristics Collaborations Collection Contracts Core Facility Data Data Collection Data Management Resources Development Diet Documentation Education Electronic Health Record Ensure Epithelial Cells Equipment and supply inventories Experimental Designs Fibroblasts Future Harvest Heart Hepatocyte Human Human Resources In Vitro Infection Information Technology Liver Lung Mesenchymal Stem Cells Mus Nebraska Organ Organ Procurements Organoids Performance Physiology Preparation Procedures Protocols documentation Reporting Research Research Personnel Resource Sharing Resources Sampling Secure Serum Services Slice Smoking Standardization Study models System Therapeutic Tissue Banks Tissue Model Tissue Sample Tissues Toxin Training Training and Education alcohol effect animal tissue biobank bioimaging bronchial epithelium computerized data processing data sharing design gastrointestinal system human disease human model human tissue innovation novel success training opportunity translational model translational research program

项目摘要

The primary function of the Biospecimen Core (BioCore) is to provide investigators of the Alcohol Center of Research-Nebraska (ACORN) key support for the novel alcohol exposome projects and their significant contributions to the field. The BioCore will provide expert assistance for the design of translational models and a centralized mechanism for animal and human sample accrual. The BioCore will ensure standardization of sample preparation and integrity; uniformity of protocols and procedures; and data collection, reporting and sharing. At a minimum, the well-governed and supported BioCore will bank and distribute animal and human samples for all four of the ACORN projects. Additionally, project milestones and deliverables will be significantly supported through a searchable online inventory, annotated sample characteristics, and the coordination and dissemination of available resources and collaborative support. Further, the BioCore will facilitate educational seminars, training, and collaborative opportunities with local and national resources to aid in the success of the alcohol exposome projects and future strategies.

生物样本核心（BioCore）的主要功能是为酒精中心的研究人员提供内布拉斯加州研究中心 (ACORN) 对新型酒精暴露组项目及其重要支持领域的贡献。 BioCore 将为转化模型的设计和动物和人类样本采集的集中机制。 BioCore将确保标准化样品制备和完整性；协议和程序的统一；以及数据收集、报告和分享。至少，管理良好和支持良好的 BioCore 将储存和分配动物和人类所有四个 ACORN 项目的样本。此外，项目里程碑和可交付成果将通过可搜索的在线库存、带注释的样本特征和协调和传播可用资源和协作支持。此外，BioCore 将促进教育研讨会、培训以及与地方和国家资源的合作机会，以提供援助酒精暴露项目的成功和未来战略。