Career Enhancement Program

职业提升计划

• 批准号: 10478022
• 负责人: Simon N. Powell
• 金额: $ 8.66万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-13 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10478022
• 关键词: Adjuvant; Breast; Breast Cancer Patient; Career Choice; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Continuity of Patient Care; DNA Repair; Defect; Development; Discipline; Disease; Disease Management; Doctor of Philosophy; Ensure; Environment; Faculty; Funding; Genetic; Genomic Instability; Goals; Grant; Immunotherapy; Individual; Institution; Investigation; Knowledge; Laboratories; Laboratory Research; Link; Malignant Neoplasms; Memorial Sloan-Kettering Cancer Center; Mentors; Mentorship; Metastatic breast cancer; Modeling; Oncology; Pathway interactions; Patient Care; Patients; Pattern; Physicians; Population; Population Sciences; Process; Research; Research Personnel; Research Project Grants; SECTM1 gene; Scientist; Source; Surgeon; Training; Translational Research; Translations; United States National Institutes of Health; Work; career; certificate program; clinical application; clinical investigation; comparative; design; experience; faculty mentor; individualized medicine; interest; investigator training; malignant breast neoplasm; member; programs; recruit; targeted agent; targeted treatment; translational cancer research; translational scientist; trend

CAREER ENHANCEMENT PROGRAM RESEARCH PLAN CEP Director: Simon Powell, MD PhD CEP Co-Director: Jorge Reis-Filho, MD PhD Abstract: The SPORE Career Enhancement Program (CEP) aims to prepare physicians and scientists for independent careers in translational research in breast cancer. Our goal is that investigators supported through this process will spend their professional lifetimes conducting translational research in breast cancer and become academic leaders in the field. Memorial Sloan Kettering Cancer Center (MSKCC) is ideally suited for this task, because of the scientific and clinical environment at our Manhattan campus and affiliated institutions, and our long tradition of training physicians and scientists of the highest quality. Our institutional environment includes numerous NIH training grants, including a K12 grant for translational science training, a T32 grant to train PhDs in translational research in Oncology, a Certificate Program in Clinical Investigation integrated with the Clinical and Translational Science Program at Weill Cornell, and a well-established junior faculty mentoring program. We plan to use the SPORE Career Enhancement funds over the next 5 years to enhance the existing formal mentoring programs. We will encourage more physician trainees to focus on translational research in breast cancer, in particular to leverage the emerging knowledge of DNA repair defects and specific patterns of genetic instability in breast cancers to deliver targeted treatments to individual breast cancer patients. We will strive to attract basic, translational and population scientists who are interested in devoting their careers to making discoveries that have a realistic potential to clinical applications. The specific aims of the MSKCC Breast SPORE Career Enhancement Program are to support the mentoring and research of junior faculty for careers in translational research in breast cancer, using a dual clinical and laboratory/population science mentorship model, and to recruit and mentor new junior faculty members to work in breast cancer translational research.

职业提升计划研究计划 CEP 主任：Simon Powell，医学博士 CEP 联合主任：Jorge Reis-Filho，医学博士 抽象的： SPORE 职业提升计划 (CEP) 旨在帮助医生和科学家做好独立工作的准备 乳腺癌转化研究的职业生涯。我们的目标是通过这一过程为调查人员提供支持 将用他们的职业生涯进行乳腺癌转化研究并成为学术界 该领域的领导者。纪念斯隆凯特琳癌症中心 (MSKCC) 非常适合这项任务，因为 我们曼哈顿校区和附属机构的科学和临床环境，以及我们悠久的传统 培训最高质量的医生和科学家。我们的机构环境包括众多 NIH 培训补助金，包括用于转化科学培训的 K12 补助金、用于培训转化科学博士的 T32 补助金 肿瘤学研究，临床研究证书课程，与临床和转化相结合 威尔康奈尔大学的科学项目以及完善的初级教师指导项目。我们计划使用 SPORE 职业发展基金将在未来 5 年内资助加强现有的正式指导计划。 我们将鼓励更多的实习医生关注乳腺癌的转化研究，特别是 利用有关 DNA 修复缺陷和乳腺遗传不稳定性特定模式的新兴知识 癌症为个体乳腺癌患者提供有针对性的治疗。我们将努力吸引基础、 有兴趣将自己的职业生涯奉献给以下发现的转化科学家和人口科学家 具有临床应用的现实潜力。 MSKCC 乳房 SPORE 职业的具体目标 增强计划旨在支持初级教师的转化职业生涯的指导和研究 使用双重临床和实验室/人口科学指导模式进行乳腺癌研究，并 招募和指导新的初级教员从事乳腺癌转化研究。