Emory Training Program in Translational Research to End the HIV Epidemic

埃默里大学终结艾滋病毒流行转化研究培训计划

• 批准号: 10475304
• 负责人: Ann M Chahroudi
• 金额: $ 49.15万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-25 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10475304
• 关键词: Epidemic; HIV; Training Programs; Translational Research

Project Abstract In this application entitled `Emory Training Program in Translational Research to End the HIV Epidemic', we propose a new T32 training program focused on translational HIV science located at the epicenter of the US HIV epidemic in the Southern US at Emory University in Atlanta, GA. Our training program will provide 2 years of support to 5 post-doctoral fellows and a summer internship opportunity for 2 pre-doctoral under- represented minority (URM) students to conduct cutting-edge HIV research through hands-on experience and formal didactics and also educate trainees on the broader context of HIV research across the translational continuum. Our training program will be fully integrated with and capitalize on the significant HIV research portfolio of the Emory Center for AIDS Research (CFAR) and span the spectrum of ongoing HIV research activities in 3 major areas of focus: 1. Laboratory-based basic science, vaccine, and cure research, 2. Patient-centered clinical research, and 3. Public health and implementation science. Our training program will encompass research activities in each of the NIH HIV/AIDS research priorities to reduce the incidence of HIV, develop next generation HIV therapeutics, conduct research towards an HIV cure, and address HIV associated co-morbidities, co-infections and complications; but, more importantly, our program will also expose trainees to cross-cutting areas of HIV research and team science to accelerate the translation of discovery into improved health outcomes. We have assembled a team of 35 diverse and experienced mentors across the 3 HIV research focus areas and designed didactic opportunities for our mentees to complement their research projects and expand their understanding of bench to bedside to community translation of HIV research innovation. In addition, the geographic position of our training program located in and surrounded by 4 of the counties named as focus areas for the Department of Health and Human Services Ending the HIV Epidemic (EHE) initiative further demonstrates the urgency to develop and support the next generation of HIV investigators specifically at our institution. Given the gravity of the HIV epidemic in the South and globally and the new DHHS initiative that proposes to end the US HIV epidemic in the next 10 years, fostering the next generation of translational HIV scientists across the HIV research continuum is of utmost importance. Post-doctoral trainees will emerge from our T32 program ready for scientific independence and with a deep understanding of how their research fits into the multidirectional and multidisciplinary framework of HIV research with the long-term goal of ending the HIV epidemic.

项目摘要 在这份题为“终结艾滋病毒流行的转化研究埃默里培训计划”的申请中， 我们提出了一个新的 T32 培训计划，重点关注位于艾滋病病毒中心的转化艾滋病毒科学 美国艾滋病毒在美国南部佐治亚州亚特兰大埃默里大学流行。我们的培训计划将提供 2 为 5 名博士后研究员提供多年支持，并为 2 名博士前学生提供暑期实习机会 代表少数族裔（URM）学生通过实践经验进行前沿的艾滋病毒研究 正式的教学法，并教育学员了解跨转化的艾滋病毒研究的更广泛背景 连续体。我们的培训计划将充分整合并利用重要的艾滋病毒研究 埃默里艾滋病研究中心 (CFAR) 的投资组合，涵盖正在进行的艾滋病毒研究范围 3 个主要重点领域的活动：1. 基于实验室的基础科学、疫苗和治疗研究，2. 以患者为中心的临床研究，以及 3. 公共卫生和实施科学。我们的培训 计划将涵盖 NIH 每个艾滋病毒/艾滋病研究重点的研究活动，以减少 艾滋病毒的发病率，开发下一代艾滋病毒疗法，开展艾滋病毒治疗研究，以及 解决与艾滋病毒相关的合并症、合并感染和并发症；但更重要的是，我们的计划 还将让学员接触艾滋病毒研究和团队科学的交叉领域，以加速转化 发现改善健康结果。我们组建了一支由 35 名多元化且经验丰富的团队组成 跨越 3 个艾滋病毒研究重点领域的导师，并为我们的学员设计了教学机会 补充他们的研究项目并扩大他们对实验室、临床和社区的理解 艾滋病毒研究创新的转化。另外，我们的培训项目的地理位置位于 周围有 4 个被卫生与公众服务部指定为重点地区的县 结束艾滋病毒流行 (EHE) 举措进一步表明了制定和支持下一个举措的紧迫性 我们机构专门培养了一代艾滋病毒研究人员。鉴于南方艾滋病毒流行的严重性 以及全球范围内的 DHHS 新倡议，该倡议提议在未来 10 年内结束美国艾滋病毒流行， 在艾滋病毒研究的连续过程中培养下一代转化艾滋病毒科学家是最重要的 重要性。博士后学员将从我们的 T32 项目中脱颖而出，为科学独立和 深入了解他们的研究如何融入多方向和多学科框架 艾滋病毒研究的长期目标是结束艾滋病毒流行。