The Development of Eating Behavior in Infancy: Associations with Behavior, Diet, and Growth to Age 6 years

婴儿期饮食行为的发展：与行为、饮食和 6 岁生长的关联

• 批准号: 10457444
• 负责人: Julie C Lumeng
• 金额: $ 61.98万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10457444
• 关键词: 5 year old; 6 year old; Address; Adult; Affect; Age; Area; Attention; Behavior; Behavioral; Body mass index; Characteristics; Child; Child Development; Childhood; Coercion; Cohort Studies; Data Collection; Desire for food; Development; Diet; Dimensions; Eating Behavior; Exposure to; Food; Funding; Future; Growth; Health; Individual; Infant; Informal Social Control; Intervention; Literature; Measures; Modeling; Nature; Outcome; Parents; Phenotype; Predictive Value; Predisposition; Protocols documentation; Public Health; Publishing; Reporting; Resources; Stimulus; Structure; Temperament; Testing; Time; United Kingdom; Weight Gain; Work; base; behavior measurement; behavioral phenotyping; cohort; dietary; early childhood; feeding; follow-up; food avoidance; high body mass index; infancy; infant temperament; intervention effect; novel; obesity risk; prospective; response; sucking; therapy development; trait

PROJECT SUMMARY Eating behaviors are robustly associated with dietary quality and weight gain. Given the relevance of eating behaviors to health in children and adults, remarkably little is known regarding the development of these behaviors from infancy, and their continuity (or discontinuity) into childhood. Eating behaviors can be phenotyped in infancy through rigorous measurement of behavior following exposure to different stimuli under careful experimental control, though no studies prior to R01HD084163 have phenotyped multiple eating behaviors objectively in a single longitudinal infant cohort. Eating behavior may be modifiable between infancy and early childhood, potentially altering any associations with future dietary quality or weight gain. Interventions that promote adaptive maternal feeding practices have been effective in reducing obesity risk. Intervention effects might be further strengthened by tailoring to characteristics of the individual child. Identifying interactions of carefully phenotyped child eating behavior and maternal feeding practices in an observational cohort study is an important initial step towards future tailored intervention development. The proposed work will examine for the first time the continuity (or discontinuity) of extensively phenotyped eating behaviors in infancy, based on novel objective measures and maternal report, to age 5 years. The work will, for the first time, test whether maternal feeding practices and infant eating behaviors interact to predict child eating behaviors at age 5 years, as well as dietary quality and BMI at age 6 years. The ABC Baby study (R01HD084163, 7/1/15-06/30/20) and its ancillary funded studies used novel behavioral protocols to phenotype eating behavior and maternal feeding practices longitudinally at ages 2 weeks, and 2, 4, 6, 9, and 12 months in a cohort of 286 infants. The current application proposes to follow up with 200 of these children at ages 5 and 6 years to address the following aims: Aim 1: To test the cross-lagged associations between child eating behaviors and maternal feeding practices across infancy and age 5 years. We hypothesize that child eating behaviors in infancy predict child eating behaviors at age 5 years, maternal feeding practices in infancy predict maternal feeding practices at age 5 years, child eating behaviors in infancy predict maternal feeding practices at 5 years, and maternal feeding practices in infancy predict child eating behaviors at 5 years. Aim 2: To test the hypothesis that eating behaviors measured in infancy have direct and indirect (through eating behaviors at age 5 years) associations with dietary quality and BMI at age 6 years. Aim 3: To test the hypotheses that maternal feeding practices in infancy moderate associations of infant eating behaviors with eating behaviors at 5 years, and that maternal feeding practices at 5 years moderate associations of eating behaviors in infancy with dietary quality and BMI at age 6 years, and moderate associations of eating behaviors at age 5 years with dietary quality and BMI at age 6 years.

项目概要 饮食行为与饮食质量和体重增加密切相关。考虑到饮食的相关性 行为对儿童和成人健康的影响，但人们对这些行为的发展知之甚少 从婴儿期开始的行为，以及它们到童年的连续性（或不连续性）。饮食行为可以是 通过严格测量暴露于不同刺激下的行为，在婴儿期表现出表型 仔细的实验​​控制，尽管在 R01HD084163 之前没有研究表明多次进食的表型 单个纵向婴儿队列中客观的行为。婴儿期之间的饮食行为可能会发生改变 和幼儿期，可能会改变与未来饮食质量或体重增加的任何关联。干预措施 促进适应性孕产妇喂养实践的做法可有效降低肥胖风险。干涉 通过针对个别儿童的特征进行调整，效果可能会进一步加强。识别 在观察中仔细表型的儿童饮食行为和母亲喂养实践的相互作用 队列研究是未来定制干预措施发展的重要第一步。拟议的工作 将首次检查广泛表型饮食行为的连续性（或不连续性） 根据新颖的客观测量和母亲报告，从婴儿期到 5 岁。这项工作将首先 时间，测试母亲喂养方式和婴儿饮食行为是否相互作用以预测儿童饮食 5 岁时的行为，以及 6 岁时的饮食质量和体重指数。 ABC 婴儿研究 （R01HD084163，7/1/15-06/30/20）及其辅助资助的研究使用新颖的行为协议 2周龄、2周龄、4周龄、6周龄、9周龄和9周龄时的纵向表型饮食行为和母亲喂养方式 286 名婴儿组成的队列中的 12 个月。当前的申请建议对其中 200 名儿童进行跟踪 5 岁和 6 岁儿童，以实现以下目标： 目标 1：测试儿童之间的交叉滞后关联 婴儿期至 5 岁的饮食行为和母亲喂养方式。我们假设那个孩子 婴儿期的饮食行为可预测儿童 5 岁时的饮食行为、母亲在婴儿期的喂养方式 预测 5 岁时母亲的喂养行为，婴儿期儿童的饮食行为预测母亲的喂养行为 5 岁时的饮食习惯和母亲在婴儿期的喂养习惯可预测儿童 5 岁时的饮食行为。目标 2： 检验婴儿期测量的饮食行为具有直接和间接（通过饮食）的假设 5 岁时的行为）与 6 岁时的饮食质量和 BMI 的关联。目标 3：测试 假设母亲在婴儿期的喂养方式会调节婴儿饮食行为与 5 岁时的饮食行为，以及 5 岁时母亲的喂养方式与饮食有一定的关联 婴儿期的行为与 6 岁时的饮食质量和 BMI 以及饮食的中度关联 5 岁时的行为、6 岁时的饮食质量和 BMI。