Hyperpolarized MRI Technology Resource Center

超极化 MRI 技术资源中心

基本信息

批准号：
10410338
负责人：
Daniel B Vigneron
金额：
$ 7.18万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-08-01 至 2027-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10410338
关键词：
2,4-Dinitrophenol Area Bioreactors Carbon Cell Culture Techniques Chemistry Client Clinical Clinical Research Collaborations Communication Communities Computer software Data Development Doctor of Philosophy Documentation Dose Educational workshop Electronic Mail Environment Equipment Event Extramural Activities Faculty Feedback Funding Generations Geography Goals Growth and Development function Human Human Resources Imaging Techniques Individual Industry International Magnetic Resonance Imaging Mentors Methods Newsletter Paper Pharmacy facility Physiologic pulse Postdoctoral Fellow Pre-Clinical Model Preparation Production Protocols documentation Publications Radiology Specialty Recipe Reporting Research Research Personnel Resources Sampling Services Site Source Sterility Surveys Techniques Technology Test Result Time Training Training Activity Training Programs Training Support Translational Research Translations Update Visit base biomedical imaging clinical translation design doctoral student driving force equipment acquisition experience human subject imaging approach imaging modality instrumentation interest lectures molecular imaging novel online resource outreach pre-clinical pre-clinical research program dissemination programs radiological imaging reconstruction research study sabbatical skills social media software development synergism technology development technology research and development tissue culture tool training opportunity virtual web site

项目摘要

Training & Dissemination Summary/Abstract The overall goal of this P41 center is to develop and disseminate novel hyperpolarized (HP) 13C MR technologies with requisite training/documentation to advance significantly this emerging molecular imaging approach for both preclinical scientific studies and clinical research. This has always been a critical aspect of the HMTRC and it will continue to develop and grow in new ways within this proposed renewal application. As defined in our Specific Aims, the HMTRC training and dissemination programs are designed to have a broad national impact for the advancement of HP C-13 MRI technology development and research. As stated in the 2021 EAC report: “The HMTRC has led the nation (and the world) in the development and translation of HP MRI through a unique combination of skills, expertise, instrumentation, environment, clinical engagement, and industry engagement, which simply does not exist elsewhere. The HMTRC will continue to serve as a critical national resource through the next funding cycle as the field of HP MRI expands and matures, particularly with the clinical translation of new HP agents, and more sites engaging in research involving human subjects. The restructured Center benefits from clear and enhanced synergy between all TR&Ds and Collaborative Projects that are more broadly geographically distributed. HMTRC programs for training and dissemination remain outstanding. Progress in the engagement and stimulation of clinical interest is nothing short of remarkable, and crucial for the continuing growth and development of this field.” This NCBIB’s Training & Dissemination in HP C-13 MRI will focused on: 1) Hands-on and formal course training of local MS/PhD students, post-docs, Radiology residents and fellows. 2) Collaborative Project (CP) investigators will receive specialized training relevant to their particular needs. 3) Junior Faculty will receive support by the department and HMTRC for specific training and mentoring to establish independent HP C-13 research programs. 4) Extramural Visitors from over 55 different sites have come to the HMTRC through the workshops, and longer individual visits to see the latest hardware & receive hands-on training and this would be expanded. 5) Hyperpolarized MRI Technology Workshops. These "hands-on" workshops provide unique information, training, and interactions focused on the technical aspects of HP 13C MR preclinical and translational research and analysis from all TRDs. 6) New Center Website will be a key component in the dissemination & training of tools, resources and technologies developed by this NCBIB. In this renewal, we will expand virtual training by providing new videos and documentation on HP 13C MR technology developments, “How-to” tutorials, training modules and recorded workshop, course lectures, & HP 13C seminar presentations. Also direct technology dissemination to CPs, SPs, & the wider HP 13C community will be supported.

培训与传播总结/摘要该 P41 中心的总体目标是开发和传播新型超极化 (HP) 13C MR 技术提供必要的培训/文件来显着推进这种新兴的分子成像方法临床前科学研究和临床研究一直是 HMTRC 的一个重要方面。将在此提议的更新应用程序中继续以新的方式发展和成长，如我们的具体规定中所定义的。 HMTRC 的培训和传播计划旨在对全国产生广泛的影响 HP C-13 MRI 技术开发和研究的进展正如 2021 年 EAC 报告中所述：“ HMTRC 通过独特的技术在 HP MRI 的开发和转化方面引领了国家（乃至世界）技能、专业知识、仪器、环境、临床参与和行业参与的结合， HMTRC 将继续作为重要的国家资源。随着 HP MRI 领域的扩展和成熟，特别是随着 HP MRI 的临床转化，下一个融资周期新的惠普代理商以及更多从事人类受试者研究的站点使重组后的中心受益。来自所有 TR&D 和更广泛的合作项目之间明确和增强的协同作用 HMTRC 的培训和传播计划仍然取得显着进展。临床兴趣的参与和激发是非常了不起的，对于持续的研究至关重要这一领域的成长和发展。” 本次 NCBIB 在 HP C-13 MRI 方面的培训和传播将侧重于： 1) 实践和正式课程培训当地硕士/博士生、博士后、放射科住院医师和研究员 2) 合作项目 (CP) 研究人员。 3) 初级教师将得到以下机构的支持部门和 HMTRC 进行专门培训和指导，以建立独立的 HP C-13 研究 4) 来自超过 55 个不同地点的校外访客通过研讨会来到 HMTRC，以及更长时间的个人访问，以查看最新的硬件并接受实践培训，并且这种情况将会扩大。 5) 超极化 MRI 技术研讨会这些“实践”研讨会提供独特的信息，重点关注 HP 13C MR 临床前和转化研究技术方面的培训和互动 6) 新中心网站将成为传播和培训的关键组成部分。本次更新中，我们将通过 NCBIB 开发的工具、资源和技术来扩展虚拟培训。提供有关 HP 13C MR 技术开发、“操作方法”教程、培训的新视频和文档模块和录制的研讨会、课程讲座和 HP 13C 研讨会演示以及直接技术。将支持向 CP、SP 和更广泛的 HP 13C 社区传播。