PTSD AND SEXUAL TRAUMA IN FEMALE METHADONE CLIENTS

女性美沙酮使用者的创伤后应激障碍和性创伤

• 批准号: 2241940
• 负责人: JESSICA M PEIRCE
• 金额: $ 1.3万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-01-10 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2241940
• 关键词: PTSD; SEXUAL; TRAUMA; FEMALE; METHADONE

This proposal will examine the association between opiate addiction and sexual assault history in female methadone maintenance clients. The link between combat-related post-traumatic stress disorder (PTSD) and substance abuse in male veterans is well-known, as is the reactivity of male opiate addicts to drug cues. Although sexual assaults is a more common cause of PTSD in women, and up to 40% of opiate addicts are female, neither issue has been addressed sufficiently in women. To further elucidate the link between sexual assault-related PTSD and opiate addiction in women, this research project will evaluate the psychological and physiological reactivity of females clients to drug, neural, and sexual assault audio cues. Measures of cue reactivity will include drug craving, euphoria, drug symptoms, mood, heart rate, blood pressure, skin conductance, skin temperature, and respiration rate. Subject groups will include clients with sexual assault-related PTSD and those without a history of either sexual assault in PTSD. This study should provide essential information on the characteristics od sexual assault-related PTSD in women, especially with regard to opiate addiction. In addition, it should allow us to determine whether women respond to drug cues in the same way as men.

该提案将研究阿片类瘾与 女性美沙酮维护客户的性侵犯历史。 链接 与战斗有关的创伤后应激障碍（PTSD）和 男性退伍军人滥用药物是众所周知的， 男性阿片类药物的吸毒者对毒品提示。 虽然性侵犯更多 女性PTSD的常见原因，多达40％的阿片类瘾君子是 女性，女性都没有足够的解决问题。到 进一步阐明与性侵犯相关的PTSD与鸦片之间的联系 女性成瘾，该研究项目将评估心理 女性对药物，神经和女性的生理反应性 性侵犯音频提示。 提示反应性的度量将包括药物 渴望，欣快感，药物症状，情绪，心率，血压，皮肤 电导，皮肤温度和呼吸速率。 主题组将 包括与性侵犯相关的PTSD的客户以及没有性侵犯的客户 PTSD中任何性侵犯的历史。 这项研究应提供 与性侵犯有关的特征的基本信息 女性的PTSD，尤其是关于阿片类成瘾的。 此外， 它应该允许我们确定妇女是否应对毒品提示 和男人一样。