Colorado's Partnership to Implement Evidence-Based Interventions to Reduce the Cancer Burden

科罗拉多州合作实施循证干预措施以减少癌症负担

• 批准号: 10409393
• 负责人: RICHARD D SCHULICK
• 金额: $ 15万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2022-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10409393
• 关键词: Address; Advisory Committees; Affect; Automobile Driving; Breast; Cancer Burden; Cancer Center; Cancer Control; Cancer Control Research; Catchment Area; Clinical; Clinics and Hospitals; Collaborations; Colonoscopy; Colorado; Colorectal; Colorectal Cancer; Communities; Community Networks; County; Data; Early Diagnosis; Environmental Exposure; Evaluation; Evidence based intervention; Federally Qualified Health Center; Goals; Health; Healthcare; Healthcare Systems; Hispanics; Hot Spot; Human; Human Papilloma Virus Vaccine; Human papilloma virus infection; Incidence; Individual; Infrastructure; Intervention; Interview; Investigation; Lung; Malignant Neoplasms; Malignant neoplasm of lung; NCI-Designated Cancer Center; Outcome; Patients; Pilot Projects; Population Decreases; Population Sciences; Positioning Attribute; Poverty; Practical, Robust Implementation and Sustainability Model; Prevention; Primary Health Care; Prostate; Public Health; Reach, Effectiveness, Adoption, Implementation, and Maintenance; Regional Cancer; Research; Research Personnel; Research Project Grants; Resources; Risk Factors; Rural Community; Screening for cancer; Services; Smoking; The University of Colorado Cancer Center; Touch sensation; Underserved Population; Universities; base; cancer health disparity; cancer prevention; cancer risk; community based participatory research; design; evidence base; improved; innovation; lung cancer screening; malignant breast neoplasm; modifiable risk; mortality; ranpirnase; research study; service gap; uptake

Abstract The University of Colorado Cancer Center (UCCC) and the Colorado Cancer Coalition (CCC) will collaborate to develop regional networks to implement cancer control interventions to reduce cancer disparities in Colorado. UCCC’s catchment area is the State of Colorado and is the only NCI-designated cancer center in the state driving cancer discovery and innovation through its basic to translational to clinical to population science investigations. The CCC is a statewide organization seeking to eliminate the cancer burden in Colorado by engaging, facilitating, expanding, and strengthening the statewide network dedicated to improving Colorado lives touched by cancer. As leaders in the state, the UCCC and CCC will bring key stakeholders from 5 regions in Colorado (Front Range, Eastern, Western, Central Mountain, and the San Luis Valley/Southern regions) to partner and meaningfully reduce the incidence, mortality, and late-stage cancers that disproportionately affect underserved populations. Coloradans affected by cancer disparities would benefit greatly from increased access and uptake cancer control evidence-based interventions (EBIs) across the cancer continuum, but specially to reduce modifiable risk factors (e.g., smoking, human papillomavirus infection, low cancer screenings). Strengthening networks of community stakeholders from primary care and public health holds great promise for the wider implementation of evidence- based interventions and to increase cancer control research in Colorado. Thus, we will convene and support 5 RCNs to build collaboration and the infrastructure needed to bolster cancer control efforts. We have determined cancer disparity counties’ needs and capacity to implement cancer control activities and to conduct research. As the next step, UCCC and CCC will convene the 5 RCNs of key stakeholders to begin planning and implementing cancer control EBIs in disparity counties and to conduct research to study the implementation of EBIs. Each network will have a Regional Planner, an individual or organization, who will oversee the implementation and the short (1-year) and long-term (5-years) evaluation of the initiatives. The planner will also coordinate regional representation in the Colorado Cancer Coalition’s Cancer Task Forces to expand the referral resources and connect smaller regions of the state to the broader coalition efforts towards decreasing the state’s cancer burden. For the second aim, the RCNs will collaborate with UCCC investigators to conduct a pilot project to study the implementation of EBIs relevant to the regional cancer priorities and to affect cancer control targets such as improving HPV vaccine rates, lung cancer screenings, and colonoscopies, among other targets. The projects proposed will use a combination of conceptual frameworks to study the implementation of EBIs, including the Reach, Effectiveness, Adoption, and Implementation, Maintenance (RE-AIM) framework, the Practical Robust Implementation and Sustainability Model (PRISM), and the Consolidated Framework for Research (CFIR), which aid in designing and evaluating the implementation of EBIs to improve the cancer control outcomes targeted.

抽象的 科罗拉多大学癌症中心 (UCCC) 和科罗拉多癌症联盟 (CCC) 将合作 发展区域网络来实施癌症控制干预措施，以减少科罗拉多州的癌症差异。 UCCC 的服务范围为科罗拉多州，是该州唯一一家 NCI 指定的癌症中心 通过基础、转化、临床、人口科学研究来发现和创新癌症。 CCC 是一个全州范围的组织，致力于通过参与、促进、 扩大和加强联邦网络，致力于改善科罗拉多州受癌症影响的生活。 作为该州的领导者，UCCC 和 CCC 将汇集来自科罗拉多州 5 个地区（Front Range、 东部、西部、中部山区和圣路易斯谷/南部地区）进行合作并有意义 减少对服务不足的人群造成不成比例影响的发病率、死亡率和晚期癌症。 受癌症差异影响的科罗拉多人将从增加癌症控制的获取和吸收中受益匪浅 跨癌症连续体的循证干预措施（EBI），但特别是为了减少可改变的风险因素 （例如吸烟、人乳头瘤病毒感染、癌症筛查率低）。 来自初级保健和公共卫生的利益相关者对更广泛地实施证据抱有巨大希望 因此，我们将召集并支持 5。 我们已决定建立 RCN 来建立支持癌症控制工作所需的合作和基础设施。 癌症各县实施癌症控制活动和开展研究的需求和能力存在差异。 下一步，UCCC和CCC将召集主要利益相关者的5个RCN，开始规划和实施 不同县的癌症控制 EBI 并开展研究以研究 EBI 的实施情况。 网络将有一名区域规划师（个人或组织），负责监督实施和 规划者还将协调区域举措的短期（1 年）和长期（5 年）评估。 科罗拉多癌症联盟癌症工作组的代表，以扩大转诊资源和 将该州较小的地区与更广泛的联盟努力联系起来，以减少该州的癌症负担。 对于第二个目标，RCN 将与 UCCC 研究人员合作开展一个试点项目来研究 实施与区域癌症优先事项相关的 EBI，并影响癌症控制目标，例如 这些项目的目标包括提高 HPV 疫苗接种率、肺癌筛查和结肠镜检查。 提议将结合使用概念框架来研究 EBI 的实施，包括 范围、有效性、采用、实施、维护 (RE-AIM) 框架，实用稳健 实施和可持续性模型（PRISM）以及综合研究框架（CFIR）， 帮助设计和评估 EBI 的实施，以改善目标癌症控制结果。