Administrative Core

行政核心

基本信息

批准号：
10216923
负责人：
CALEB E FINCH
金额：
$ 19.84万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10216923
关键词：
Advisory Committees Aging Air Pollution Alzheimer&apos s disease risk Biology Blood Vessels Brain Brain imaging California Clinical Collaborations Communities Data Environmental Epidemiology Environmental Exposure Environmental Health Epidemiology Expenditure Exposure to Faculty Finches Fostering Funding Goals Group Meetings Health Sciences Heterogeneity Human Resources Individual Informatics Infrastructure Inhalation Exposure Institutes Institution Joints Leadership Memory Mind Modeling Monitor Mus Neurobiology Neurologic Effect Neurology Neuropsychology Population Positioning Attribute Program Research Project Grants Research Research Personnel Resources Risk Science Scientist Services Site Universities Videoconferencing Washington ambient air pollution base career development cognitive neuroscience forest medical schools meetings member neurogenetics neuroimaging neurosurgery neurotoxicology operation performance site programs ranpirnase recruit

项目摘要

The Administrative Core supports this interdisciplinary and multi-university team of investigators. The P01 program has three performance sites: the USC University Park Campus (Core C, Projects 3); USC Health Science Campus (Core B, Projects 1 & 4); and University of California, San Diego (Project 2). The proposed program includes an established group of collaborative scientists with expertise in neurobiology of AD, population neuroimaging, mouse brain imaging, brain vascular biology, clinical neurology, cognitive neurosciences, neuropsychology, epidemiology of AD, large-scale air pollution modeling, environmental epidemiology, inhalation exposure assessment and neurotoxicology. The specific aims of the Administrative Core are: 1) Provide the integrated program leadership and coordination; (2) Strengthen existing partnerships, facilitate new collaborations and foster the career development of junior investigators/trainees across USC and participating institutes; (3) Assess scientific progress of the program, through joint group meetings per month, work-in-progress meetings per quarter, and annual meetings of the project-core leaders and key personnel with the External Advisory Committee; (4) Provide fiscal management and administrative services and monitor resources and expenditures; (5) Carry out the joint dissemination of study results to the broader scientific community. The Administrative Core will provide leadership, oversight, planning, and coordination to facilitate scientific integration and synthesis across projects, promote cross-disciplinary interactions, and support multi- site operation of proposed program activities. The collaborative infrastructure of the proposed P01 is the product of the AirPollBrain (PIs: Finch & Chen), a collaborative network funded by USC since 2010. Over the last few years, the AirPollBrain has developed partnerships with several USC-based Centers/Institutes in brain sciences (e.g., ADRC/Memory and Aging Center, Zilkha Neurogenetic Institute, Mark and Mary Stevens Neuroimaging and Informatics Institute; Institute of Developing Mind) and also helped create the new Research Program on Neurological Effects of Environmental Exposure for the latest renewal of Southern California Environmental Health Sciences Center (P30 ES007048-20). The Administrative Core is well positioned to leverage these institutional resources and maximize the impact of the proposed P01 research.

行政核心支持这个跨学科和多大学的研究团队。 P01 项目共有三个表演场地：南加州大学公园校区（核心 C，项目 3）；南加州大学健康中心科学校园（核心 B，项目 1 和 4）；和加州大学圣地亚哥分校（项目 2）。拟议的计划包括一组在 AD 神经生物学方面具有专业知识的合作科学家，群体神经影像、小鼠脑成像、脑血管生物学、临床神经病学、认知神经科学、神经心理学、AD流行病学、大规模空气污染模型、环境流行病学、吸入暴露评估和神经毒理学。行政核心的具体目标是： 1）提供综合计划的领导和协调；（二）加强现有合作伙伴关系，促进新的合作，促进青年人的职业发展南加州大学和参与机构的研究人员/实习生； (3) 通过每月联合小组会议、正在进行的工作评估项目的科学进展项目核心领导和关键人员与外部的季度会议和年度会议咨询委员会； (4) 提供财政管理和行政服务并监控资源和支出； (5) 向更广泛的科学界联合传播研究成果。行政核心将提供领导、监督、规划和协调，以促进跨项目的科学整合和综合，促进跨学科互动，支持多方合作拟议计划活动的现场运作。拟议的 P01 的协作基础设施是 AirPollBrain（PI：Finch & Chen）的产品，该网络是南加州大学自 2010 年以来资助的一个协作网络。过去几年，AirPollBrain 与位于南加州大学的多个脑研究中心/研究所建立了合作伙伴关系科学（例如 ADRC/记忆与衰老中心、Zilkha 神经遗传学研究所、Mark 和 Mary Stevens 神经影像和信息学研究所；发展心智研究所），还帮助创建了新的研究南加州最新更新的环境暴露神经影响计划环境健康科学中心（P30 ES007048-20）。行政核心处于有利地位利用这些机构资源并最大限度地发挥拟议 P01 研究的影响。