Yale SPORE in Lung Cancer Developmental Research Program

耶鲁大学 SPORE 肺癌发展研究项目

• 批准号: 10203857
• 负责人: Roy S Herbst
• 金额: $ 8.96万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-26 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10203857
• 关键词: Agreement; Area; Award; Biology; Budgets; Caliber; Cancer Biology; Carcinogenesis Mechanism; Clinical; Collaborations; Committee Members; Communities; Consultations; Development; Direct Costs; Electronic Mail; Ensure; Financial Support; Fostering; Funding; Funding Mechanisms; Future; Goals; Guidelines; Human; Institution; Leadership; Malignant Neoplasms; Malignant neoplasm of lung; Methods; Monitor; Morbidity - disease rate; Outcome; Pilot Projects; Prediction of Response to Therapy; Process; Productivity; Prognosis; Program Research Project Grants; Recruitment Activity; Research; Research Personnel; Research Project Grants; Resource Sharing; Risk Assessment; Study Section; Translations; United States National Institutes of Health; Woman; Work; Yale Cancer Center; anticancer research; cancer therapy; early detection biomarkers; innovation; meetings; member; minority investigator; mortality; new therapeutic target; novel; novel therapeutics; personalized medicine; programs; recruit; translational research program; tumorigenesis

PROGRAM SUMMARY The primary goal of the Developmental Research Program (DRP) of the Yale SPORE in Lung Cancer (YSILC) is to identify and fund innovative pilot projects that possess translational potential for making an impact in the field of lung cancer in the areas of risk assessment; early detection; biomarkers for prognosis, therapy, and prediction; biology; and novel treatment approaches. Investigators and projects of funded developmental research projects are strongly encouraged to collaborate with other investigators within and outside of Yale, including other SPORE research communities, with the goal that these projects will evolve into independent full SPORE projects or equivalent scale studies. The objective of the YSILC DRP is to develop innovative lung cancer translational research programs. To achieve this goal, we propose the following three specific aims: Specific Aim 1. To identify and recruit innovative pilot projects with translational potential for lung cancer. Specific Aim 2. To support new research opportunities for lung cancer by funding innovative pilot projects. Specific Aim 3. To enhance collaborations between SPORE full research projects and DRP investigators (current and potential) and to promote DRP projects to potential full SPORE or equivalent scale projects. Pilot projects funded by the DRP mechanism are strongly encouraged to collaborate with intra- and inter- SPORE projects. Projects making significant progress will be considered for incorporation into a full project if there are any programmatic needs and upon agreement of the YSILC leadership in consultation with the Internal Advisory Board, External Advisory Board and NCI staff.

计划概要 耶鲁 SPORE 肺癌发展研究计划 (DRP) (YSILC) 的主要目标 是确定并资助具有转化潜力的创新试点项目，对世界产生影响 肺癌领域的风险评估；及早发现；用于预后、治疗和治疗的生物标志物 预言;生物学;和新颖的治疗方法。资助发展的研究人员和项目 强烈鼓励研究项目与耶鲁大学内外的其他研究人员合作， 包括其他 SPORE 研究社区，目标是这些项目将发展成为独立的完整项目 SPORE 项目或同等规模的研究。 YSILC DRP 的目标是开发创新型肺 癌症转化研究计划。为实现这一目标，我们提出以下三个具体目标： 具体目标 1. 识别和招募具有肺癌转化潜力的创新试点项目。 具体目标 2. 通过资助创新试点项目来支持肺癌的新研究机会。 具体目标 3. 加强 SPORE 完整研究项目和 DRP 研究人员之间的合作 （当前和潜在）并将 DRP 项目推广为潜在的完整 SPORE 或同等规模的项目。 强烈鼓励 DRP 机制资助的试点项目与内部和外部合作 孢子项目。取得重大进展的项目将被考虑纳入一个完整的项目，如果 有任何计划需求，并经 YSILC 领导层与 内部顾问委员会、外部顾问委员会和 NCI 工作人员。