Consortium-Wide Coordinating Core

联盟范围内的协调核心

• 批准号: 10194365
• 负责人: MICHAEL L TERRIN
• 金额: $ 20.4万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-16 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10194365
• 关键词: Acute; Advanced Development; Animal Model; Animals; Archives; Basic Science; Biocompatible Materials; Bioinformatics; Biological Markers; Biometry; Businesses; Calendar; Cellular biology; Collaborations; Communication; Communities; Computer software; Data; Data Coordinating Center; Documentation; Educational Activities; Educational Materials; Equipment; Event; Funding; General Population; Information Centers; Information Dissemination; Infrastructure; Link; Medical center; Methods; Modeling; Monitor; National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Disease; Nature; Pilot Projects; Procedures; Protocols documentation; Publications; Radiation; Radiation Syndromes; Radiobiology; Reagent; Research; Research Personnel; Resources; Running; Schedule; Specimen; System; Time; Training and Education; Translational Research; U-Series Cooperative Agreements; United States National Institutes of Health; Update; data exchange; data sharing; experience; innovation; interest; medical countermeasure; meetings; programs; radiation countermeasure; response; social media; stem cells; symposium; web page; web site

Abstract We propose to meet the need of the NIAID Centers for Medical Countermeasures Against Radiation Consortium (CMCRC) for 1) administrative infrastructure to organize interactions and facilitate collaboration among CMCRC investigators, 2) oversight of programs using funds to stimulate Pilot Studies, 3) timely sharing of CMCRC-generated data, biomarkers, (animal) models and reagents among CMCRC investigators and with the research community, and, 4) biostatistics and bioinformatics support, in response to AI-10-012, with staff who bring years of experience working along similar lines in the NHLBI Progenitor Cell Biology Consortium (PCBC) Administrative Coordinating Center (ACC) and the Progenitor Cell Translational Consortium (PCTC) Administrative Coordinating Center (ACC). The proposed investigators and staff have extensive experience in coordinating centers, organization of meetings, collaborative research under cooperative agreements, consortium infrastructure, web site, communications, monitoring and documentation. We will adapt and advance our infrastructure (hardware, software, web sites and links, offices, office equipment and staff) in place for the PCBC ACC and PCTC ACC to extend to the CMCRC resulting in an immediate, running start for the CMCRC Consortium-wide Coordinating Center (CCC) on day one. We will proceed to expand the functions of the extant infrastructure to additional, innovative use of social media to reach all corners of the CMCRC community and out to the broader research community. The CMCRC Consortium-wide Coordinating Center will follow procedures it has established and is using for other NIH- supported coordinating centers to perform administrative tasks necessary to conduct consortium meetings and conference calls, prepare agendas and minutes, administer funds for training and education and support a web site for communications, transmission of data, information and descriptions of methods (e.g., protocols) and requests for reagents, biomaterials and (animal) models to be shared. Our proposal is both highly efficient and innovative because of the expertise and experience of our investigators, the uninterruptable nature of their backup for each other and the uninterruptable nature of the systems we will extend and update from the PCBC and PCTC to the CMCRC. The channeling of resources to translational research, basic research necessary to support translational research and the extension of our infrastructure through social media will be substantial.

抽象的 我们建议满足 NIAID 辐射医学对策中心的需求 1) 组织互动和促进协作的行政基础设施联盟 (CMCRC) 在 CMCRC 调查人员中，2）监督使用资金刺激试点研究的项目，3）及时共享 CMCRC 生成的数据、生物标志物、（动物）模型和试剂在 CMCRC 研究人员中以及 研究界，以及，4) 生物统计学和生物信息学支持，响应 AI-10-012，与工作人员 他们在 NHLBI 祖细胞生物学联盟中拥有多年类似工作经验 (PCBC) 行政协调中心 (ACC) 和祖细胞转化联盟 (PCTC) 行政协调中心（ACC）。拟议的研究人员和工作人员在以下方面拥有丰富的经验 协调中心、会议组织、合作协议下的合作研究、 联盟基础设施、网站、通信、监控和文档。 我们将调整和推进我们的基础设施（硬件、软件、网站和链接、办公室、办公室 PCBC ACC 和 PCTC ACC 延伸到 CMCRC 的设备和人员）到位，从而导致 第一天，CMCRC 联盟协调中心 (CCC) 立即开始运行。我们将 继续扩大现有基础设施的功能，以更多、创新的方式使用社交媒体 覆盖 CMCRC 社区的各个角落以及更广泛的研究社区。 CMCRC 联盟范围内的协调中心将遵循其已制定并用于其他 NIH 的程序 支持协调中心执行举行联盟会议和会议所需的行政任务 电话会议、准备议程和会议记录、管理培训和教育资金并支持网络 用于通信、数据传输、信息和方法描述（例如协议）的站点以及 请求共享试剂、生物材料和（动物）模型。 由于我们的专业知识和经验，我们的建议既高效又创新 调查员、他们相互支持的不间断性质以及 我们将从 PCBC 和 PCTC 扩展到 CMCRC 系统并进行更新。资源引导 转化研究、支持转化研究和扩展我们的研究所必需的基础研究 通过社交媒体建立的基础设施将是巨大的。