The University of Iowa Clinical and Translational Science Award

爱荷华大学临床和转化科学奖

• 批准号: 10201104
• 负责人: Marlan R Hansen
• 金额: $ 9.89万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-03-30 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10201104
• 关键词: Affect; Age; Area; Artificial Intelligence; Automobile Driving; Award; COVID-19; Caring; Center for Translational Science Activities; Clinic; Clinical; Clinical Data; Clinical Research; Clinical Sciences; Clinical and Translational Science Awards; Clinics and Hospitals; Communities; Community Practice; Computerized Medical Record; Data; Data Element; Data Set; Data Sources; Development; Discipline; Disease; E-learning; Emergency Situation; Family Physicians; Future; Genomics; Geography; Goals; Health; Health system; Healthcare; Home environment; Human; Human Subject Research; Image; Infrastructure; Institutes; Institutional Review Boards; Iowa; Knowledge; Lead; Life; Longevity; Machine Learning; Medical Care Team; Methods; Mission; Modeling; Outcome; Patient Participation; Patients; Performance; Pharmaceutical Preparations; Pharmacists; Phenotype; Positioning Attribute; Process; Research; Research Personnel; Research Project Grants; Resources; Rural; Rural Health; Rural Population; School Nursing; Services; System; Testing; Time; Training; Transfer Agreement; Translational Research; Translations; Universities; Work; base; biomedical informatics; catalyst; clinical decision support; cohort; collaborative approach; community organizations; coronavirus disease; data acquisition; data enclave; data exchange; data resource; data sharing; data warehouse; efficacy testing; evidence base; health management; improved; informatics infrastructure; innovation; interest; member; novel; novel strategies; pandemic disease; phenotypic data; programs; rurality; social determinants; support tools; translational scientist

ABSTRACT The Institute for Clinical and Translational Science (ICTS) at the University of Iowa (UI) was established by the Board of Regents to realize three objectives – first, to lead the development of translational science at the UI; second, to advance translational science as a distinct academic discipline; and third, to disseminate capacities in translational science across the State of Iowa. This mandate enabled us to tackle large problems affecting translational science that required institutional solutions, such as transforming regulatory processes for human subjects research, developing an informatics infrastructure for integrating electronic medical record and other health care data, establishing bi-directional relationships with community organizations, and revitalizing the pipeline of well trained clinical and translational researchers. Iowa is a rural state, which brings special health care needs and challenges. We have used these rural considerations as a catalyst for driving our approach to clinical and translational research pushing our teams to develop strategies to engage rural populations of all ages and backgrounds and to create new approaches that overcome the geographic barriers in a rural state. We are capitalizing on our established community practice networks of family physicians, clinics, school nurses and pharmacists. We utilize e Health/ e Learning platforms in novel ways and will test the efficacy of these new methods of engagement. As we move research “Beyond Our Borders,” we have created methods to capture real-time, real-life data from the home and to correlate this environmentally specific, comprehensive data to human performance. The ICTS is engaging with other CTSA hubs and national CTR systems to empirically test different approaches and to develop the evidence base of proven strategies for accelerating translation that can be more broadly disseminated. Though distance and rurality drive our approaches, the strategies that we develop are simply new and potentially better ways to generate broad representation and improved participation by patients, healthcare teams and academicians. Through our local, state and national partnerships, UI and the ICTS are poised to move clinical and translational discovery rapidly into healthcare practice in a variety of clinical settings.

抽象的 爱荷华大学 (UI) 临床与转化科学研究所 (ICTS) 由 董事会将实现三个目标——第一，引领伊利诺伊大学转化科学的发展； 第二，推动转化科学成为一门独特的学科；第三，传播能力； 这项任务使我们能够解决影响爱荷华州的转化科学问题。 需要制度解决方案的转化科学，例如改变人类的监管流程 课题研究，开发集成电子病历和其他信息的信息学基础设施 医疗保健数据，与社区组织建立双向关系，并振兴社区 训练有素的临床和转化研究人员的管道。 爱荷华州是一个农村州，这给我们带来了特殊的医疗保健需求和挑战。 作为推动我们临床和转化研究方法的催化剂，推动我们的团队 制定战略，让所有年龄和背景的农村人口参与进来，并制定新的方法 我们正在利用我们既定的社区实践克服农村地区的地理障碍。 我们利用家庭医生、诊所、学校护士和药剂师网络。 我们将以新颖的方式建立平台，并将在我们开展研究时测试这些新参与方法的有效性。 “超越我们的国界”，我们创建了从家里捕获实时、真实数据的方法，并 这将环境特定的综合数据与人类绩效联系起来。 其他 CTSA 中心和国家 CTR 系统，以实证测试不同的方法并开发 加速翻译的经过验证的策略的证据基础可以更广泛地传播。 距离和乡村推动了我们的方法，我们制定的策略是全新的，并且可能会更好 如何产生广泛的代表性并提高患者、医疗团队和 通过我们地方、州和国家的合作伙伴关系，UI 和 ICTS 准备推动临床发展。 并将发现迅速转化为各种临床环境中的医疗保健实践。