Translational Immunology Training Program

转化免疫学培训计划

• 批准号: 10186683
• 负责人: Peter Scott Heeger
• 金额: $ 37.94万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10186683
• 关键词: Immunology; Training Programs

Project Summary/Abstract This is a revised, competitive renewal, T32 application in which we have coalesced and reconfigured two previously distinct and successful T32 programs at the Icahn School of Medicine at Mount Sinai (ISMMS), a post-doc program in Transplant Immunology [(P Heeger, former program director (PD)] and a pre-/post-doc program in Immunology (S Lira, former PD), into an expanded pre- and post-doctoral training program in Translational Immunology (P Heeger and S Lira Co-PDs). Combining the programs will a) enhance translational immunology training (including training in transplantation) through cross fertilization (e.g. exposing trainees in cancer immunology to transplant immunology, immunodeficiency and autoimmunity through a joint training venue) b) leverage common training faculty and institutional resources, as well as a revised immunology-focused, administrative infrastructure (including education, career development and evaluation processes) to enhance function and efficiency of the training experience, and c) limit overlap among training faculty. Additional rationale include 1) our success over the past 16 years in attracting and training pre- and post-doctoral MD, PhD and MD/PhD trainees into immunology research careers, 2) the continued need for improving outcomes of immune-mediated diseases 3) our desire to positively impact the education of future basic and translational investigators in immunology, and 4) the fact that our training environment and research foci are well-suited to offer diverse basic and translational immunology research opportunities for trainees. The exceptional ability of Mount Sinai's immunology community to make fundamental discoveries, to translate the results into novel and effective diagnostic and therapeutic strategies, and to incorporate pre- and post-doc training into its research mission underscores the significance of this revised training program. The overall objective of this program is to attract and train talented MD/PhD and PhD students and post-docs over 2 year periods, for successful, independent careers in immunology relevant to human disease. We have a diverse, well-funded faculty with broad interest in immunology and a strong pool of pre- and post-doc trainees that includes significant numbers of underrepresented minorities. The program is designed to provide training by individual mentors performing research in all aspects of Immunology relevant to human disease. The program is supported with strong oversight and administrative structure, significant didactic training in Immunology, scientific writing and career development, and contains newly added state of the art evaluation approaches with defined goals and benchmarks for success so as to optimize the development of independent academic researchers in the field.

项目概要/摘要 这是一个经过修订的、竞争性更新的 T32 应用程序，我们在其中合并并重新配置了两个 西奈山伊坎医学院 (ISMMS) 先前独特且成功的 T32 项目 移植免疫学博士后项目 [（P Heeger，前项目主任 (PD)] 和博士前/博士后 免疫学项目（S Lira，前PD），扩展为博士前和博士后培训项目 转化免疫学（P Heeger 和 S Lira Co-PD）。结合这些程序将 a) 增强 通过交叉受精（例如暴露 癌症免疫学学员通过联合移植免疫学、免疫缺陷和自身免疫 培训地点）b）利用共同的培训师资和机构资源，以及修订后的培训资源 以免疫学为重点的行政基础设施（包括教育、职业发展和评估 流程）以增强培训体验的功能和效率，以及 c）限制培训之间的重叠 学院。其他理由包括 1) 我们在过去 16 年中在吸引和培训学前和学前教育方面取得了成功 博士后医学博士、博士和医学博士/博士生进入免疫学研究职业，2) 持续需要 改善免疫介导疾病的结果 3) 我们希望对未来的教育产生积极影响 免疫学的基础和转化研究人员，以及 4) 我们的培训环境和研究 foci 非常适合为学员提供多样化的基础和转化免疫学研究机会。这 西奈山免疫学界做出基本发现、转化 结果转化为新颖有效的诊断和治疗策略，并将博士前和博士后纳入 研究任务培训强调了这一修订后的培训计划的重要性。整体 该计划的目标是吸引和培训有才华的医学博士/博士生和博士后，为期两年 时期，在与人类疾病相关的免疫学领域取得成功、独立的职业生涯。我们拥有多元化、 资金雄厚、对免疫学有广泛兴趣的教师队伍以及大量博士前和博士后实习生 包括大量代表性不足的少数族裔。该计划旨在提供培训 个人导师在与人类疾病相关的免疫学的各个方面进行研究。该计划 得到强有力的监督和管理结构、重要的免疫学教学培训的支持， 科学写作和职业发展，并包含新添加的最先进的评估方法 具有明确的目标和成功基准，以优化独立学术的发展 该领域的研究人员。