Advancing Native American Diversity in Aging Research through Undergraduate Education (Native American ADAR)

通过本科教育促进美国原住民老龄化研究的多样性（美国原住民 ADAR）

基本信息

批准号：
10172529
负责人：
GERALD SCHATTEN
金额：
$ 38.41万
依托单位：
MAGEE-WOMEN'S RES INST AND FOUNDATION
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-15 至 2026-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10172529
关键词：
Achievement Active Learning Aging Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Attention Biological Biology of Aging Boston COVID-19 pandemic Cherokee Indian Doctor of Philosophy Education Education Projects Elderly Ensure Exercise Faculty Funding Goals Institute of Medicine (U.S.)Institutes Instruction Investigation Investments Laboratories Learning Medical Melissa Mentors Metabolism Minnesota Monitor Native Americans Nature Outcome Participant Plant Roots Population Recording of previous events Research Research Personnel Research Training Scientist Student recruitment Training Training and Education Tribes Underrepresented Minority United States National Institutes of Health Universities Update Vocational Guidance aging population career college cost effective design education research health disparity improved innovation lectures medical schools minority scientist minority trainee next generation non-Native participant retention peer programs recruit response training opportunity treatment strategy undergraduate education undergraduate student virtual virtual education

项目摘要

PROJECT SUMMARY This application, responsive to PAR-17-290, seeks R25 funding for “Advancing Native American Diversity in Aging Research through Undergraduate Education.” By offering annual courses and mentored research—along with online virtual education and mentoring during this COVID-19 pandemic—we recruit students from Native American backgrounds, both urban and non-urban, to encourage them to pursue careers investigating Alzheimer’s disease and related dementias (ADRD) and aging mechanisms, and help to launch their scientific careers. The ADRD and aging fields continue to grow swiftly, as does the elderly population, yet there are too few laboratories led by under-represented minority (URM) scientists, let alone Native American PIs, and too few new URM trainees. This R25 is directed by Gerald Schatten, PhD (Pitt), and Laura Niedernhofer, MD, PhD (Minnesota), who join David Burgess, PhD (Cherokee, Boston College); Melissa Wells, PhD (Bois Forte & Couchiching First Nation Anishinaabe, Johns Hopkins - Duluth); Paul Robbins, PhD (Minnesota); and Calvin Simerly, PhD (Pitt) as the Executive Committee. The course is held at Minnesota’s Institute on the Biology of Aging and Metabolism, directed by Laura Niedernhofer, MD, PhD, and Paul Robbins, PhD. Daily lectures, active learning, and extended discussions on emerging concepts, followed by lab and group exercises and informal seminars are held over a week (August 15-21, 2021). Both hands-on and online training for 16 participants on recent discoveries regarding ADRD’s root causes and treatments is presented, with special attention devoted to Native Americans; the biology of aging is also considered. Frequent interactions are maintained with each trainee afterwards, to evaluate the course and provide ongoing mentoring. Conducted with sensitivity to tribal histories, five specific aims are proposed: I. Provide conceptual education and research training in ADRD and the Biology of Aging, with relevance for Native American trainees; II. Support mentored pilot research, especially involving challenges in health disparities and diversity related to Native Americans; III. Encourage trainees’ and alumni’s longer-term career planning through personal coaching, mentoring sessions, and peer-to-peer advice; IV. Discuss NIH regulatory requirements within the context of Tribal Sovereignty; and V. Evaluate, improve, and monitor the Native American ADAR’s strengths and avoid weaknesses with unbiased, quantitative, independent mechanisms which track trainees’ and alumni’s achievements to ensure that the program is a wise, cost-effective investment. In so doing, we will enhance and expand the research careers of promising trainees, especially Native Americans, to help ensure full diversity in the NIA and NIH.

项目概要该申请响应 PAR-17-290，寻求 R25 资金用于“推进本土通过本科教育实现美国老龄化研究的多样性。” 年度课程和指导研究——以及在线虚拟教育和指导这次 COVID-19 大流行——我们招收来自美国原住民背景的学生，其中包括城市学生和非城市地区，鼓励他们从事研究阿尔茨海默病的职业，相关痴呆症（ADRD）和衰老机制，并帮助他们开展科学事业。 ADRD 和老龄化领域继续快速增长，老年人口也是如此，但仍有由代表性不足的少数族裔（URM）科学家领导的实验室太少，更不用说本土科学家了美国的 PI，新的 URM 学员太少了。这个 R25 是由 Gerald Schatten 博士指导的。（皮特）和 Laura Niedernhofer 医学博士、哲学博士（明尼苏达州），他们与 David Burgess 博士（切罗基、波士顿学院）；Melissa Wells 博士（Bois Forte 和 Couchiching First Nation Anishinaabe，约翰斯）霍普金斯 - 德卢斯）；Paul Robbins 博士（明尼苏达州）和 Calvin Simerly 博士（皮特）；执行委员会该课程在明尼苏达州衰老生物学研究所举行。新陈代谢，由 Laura Niedernhofer 医学博士和 Paul Robbins 博士指导，每日讲座。主动学习，对新兴概念进行深入讨论，然后进行实验室和小组讨论练习和非正式研讨会为期一周（2021 年 8 月 15 日至 21 日）。为 16 名参与者提供有关 ADRD 根本原因和最新发现的在线培训提出了治疗方法，特别关注美洲原住民的衰老生物学；事后还考虑与每个学员保持频繁的互动，以进行评估。课程并提供持续的指导，对部落历史敏感，五。提出了具体目标： I. 提供 ADRD 方面的概念教育和研究培训衰老生物学，与美国原住民受训者相关；支持指导飞行员 II。研究，特别是涉及与原住民相关的健康差异和多样性挑战美国人； III. 鼓励学员和校友进行个人的长期职业规划。 IV. 讨论 NIH 的监管要求；在部落主权的范围内；以及 V. 评估、改进和监控原住民美国ADAR扬长避短，公正、量化、独立跟踪学员和校友成就的机制，以确保该计划是一个通过这样做，我们将加强和扩大研究事业。有前途的学员，特别是美洲原住民，帮助确保国家情报局和国家卫生研究院的充分多样性。