Post-Hurricane Cancer Care: Patient Needs after Hurricane Maria

飓风后癌症护理：飓风玛丽亚后的患者需求

• 批准号: 10172476
• 负责人: Eida Maria Castro
• 金额: $ 21.27万
• 依托单位: PONCE SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-17 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10172476
• 关键词: Affect; Alcohols; Anxiety; Biological; Biological Markers; Biological Process; Blood Banks; COVID-19; COVID-19 pandemic; Camping; Cancer Patient; Caring; Catecholamines; Categories; Cessation of life; Chronic; Complement; Data; Disasters; Earthquakes; Eating Behavior; Economics; Environmental Hazards; Exercise; Exposure to; Floods; Funding; Geological Survey; Grant; Hair; Health; Health Services Accessibility; Health behavior; Healthcare; Home environment; Homelessness; Hormones; Hurricane; Hydrocortisone; Inflammation; International; Island; Knowledge; Lead; Malignant Neoplasms; Measures; Medical; Mental Depression; Mental Health; Minority Groups; Natural Disasters; Outcome; Parents; Participant; Pathway interactions; Patient Care; Patient Self-Report; Patients; Physiological; Pilot Projects; Positioning Attribute; Principal Investigator; Property; Puerto Rican; Puerto Rico; Reporting; Research; Sampling; Scientist; Smoking Behavior; Social isolation; Social support; Stress; Structure; Time; Unemployment; United States; biological adaptation to stress; cancer care; circulating biomarkers; cohort; comorbidity; cytokine; environmental stressor; ethnic minority population; experience; food shortage; hazard; health care availability; health care quality; health care service; health disparity; inflammatory marker; innovation; minority health; multilevel analysis; pandemic disease; parent grant; perceived stress; predictive modeling; programs; psychologic; psychological stressor; recruit; social stressor; stress management; stressor; tumor progression

PROJECT SUMMARY Studies evaluating the effects of natural disasters on cancer outcomes and disparities are scarce, and to the study team’s knowledge; none have examined the impact of exposure to multiple disasters, particularly in ethnic minority groups. Currently, the team is expanding assessments to include the impact of COVID-19 and the earthquakes’ secondary hazards (social isolation, unemployment, healthcare services disruption, structural damage) on stress biomarkers and changes in multilevel determinants of health. The proposed supplement will complement the scope of the parent R21 (1R21MD013674) by: 1) expanding recruitment to include additional cancer patients (+75) and controls (+75) who were exposed to Maria, the 2020 earthquakes, and the COVID-19 pandemic; 2) identifying patients’ unmet psychological and medical needs resulting from the aftermath of the 2020 earthquakes and the COVID-19 pandemic, and; 3) examining the impact of Maria, the earthquakes, and the COVID-19 pandemic on multilevel factors relevant to health outcomes. The proposed supplement project will shift current research paradigms in health outcomes after natural disasters by exploring the physiological effects of extreme stressors on biological processes known to affect cancer progression and comorbid conditions, including inflammation and stress hormones. By expanding the parent grant’s scope to include the 2020 earthquakes and COVID-19 pandemic, the study team will increase the understanding of the effects of multiple disaster stressors.

项目概要 评估自然灾害对癌症结果和差异的影响的研究很少，而且 研究团队的知识；没有人研究过遭受多种灾害的影响，特别是对种族的影响 目前，该团队正在扩大评估范围，以纳入 COVID-19 和 地震的次生灾害（社会孤立、失业、医疗服务中断、结构性灾害） 拟议的补充将涉及压力生物标志物和多层次健康决定因素的损害变化。 通过以下方式补充母体 R21 (1R21MD013674) 的范围：1) 扩大招募范围以包括额外的 暴露于玛丽亚、2020 年地震和 COVID-19 的癌症患者 (+75) 和对照组 (+75) 2）确定患者因疫情后果而未得到满足的心理和医疗需求 2020 年地震和 COVID-19 大流行，以及；3) 检查玛丽亚地震的影响； COVID-19 大流行对与健康结果相关的多层次因素的影响 拟议的补充项目。 将通过探索自然灾害后的生理学结果来改变当前的研究范式 极端压力源对已知影响癌症进展和共病的生物过程的影响 扩大家长补助金的范围以包括炎症和应激激素。 2020 年地震和 COVID-19 大流行，研究团队将加深对地震影响的了解 多重灾难压力源。