Expansion of SARS-CoV-2 Testing Supplement, Chicago Clinical Trials Unit

芝加哥临床试验中心 SARS-CoV-2 检测补充的扩展

• 批准号: 10166472
• 负责人: Babafemi O Taiwo
• 金额: $ 81.41万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-06-17 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10166472
• 关键词: 2019-nCoV; AIDS prevention; AIDS/HIV problem; Address; Adult; Area; Award; Bacterial Drug Resistance; Chicago; Clinical; Clinical Research; Clinical Trials Unit; Communities; Community Participation; Development; HIV; Health; Hepatitis; Human Resources; Illinois; Laboratories; National Institute of Allergy and Infectious Disease; Parents; Performance; Persons; Pharmacy facility; Population Heterogeneity; Positioning Attribute; Prevention; Prevention strategy; Productivity; Research; Research Personnel; Research Priority; Resources; Risk; Scientific Advances and Accomplishments; Testing; Therapeutic; Tuberculosis; United States; Universities; Vaccines; Wellness Center; clinical research site; comorbidity; effective therapy; ethnic diversity; experience; metropolitan; prevent; programs; racial diversity; research study; treatment strategy; urban area

Parent Award Project Summary The Chicago Clinical Trials Unit (CCTU) is a consortium of five Clinical Research Sites (CRSs) which will address three priority clinical research areas of the NIAID: 1) adult HIV therapeutic strategies including HIV cure, noninfectious comorbidities, and infectious co-morbidities of hepatitis and tuberculosis; 2) vaccines to prevent HIV; and 3) integrated HIV prevention strategies. The CCTU consists of five highly experienced and scientifically productive CRSs that are uniquely positioned to develop, implement and adapt the clinical research priorities of the NIAID clinical research priority areas. The CCTU has a proven track record and will continue its productivity through active engagement with a diverse host of at risk and HIV-impacted communities, participation in high impact, ground-breaking clinical research studies, efficient management of resources and critical performance oversight of the clinical activities, laboratories, and pharmacies. The CCTU includes CRSs and personnel that have long term and productive involvement with three of the research networks; the fourth-antibacterial resistance-being a new network in this consortium. The CRSs and their network affiliations include: Northwestern University (adult HIV therapeutic strategies); University of Illinois Chicago (vaccines to prevent HIV, integrated HIV prevention), Rush University (adult HIV therapeutic strategies), University of Chicago (integrated HIV prevention strategies) and Trinity Health & Wellness Center (adult HIV therapeutic strategies). Four of the CRSs are located in Chicago, an ethnically and racially diverse urban area of 9.5 million persons that is the third largest metropolitan region in the United States and one of the major urban HIV epicenters. The aims of this proposal are: development, implementation and adaptation of the clinical research program of the 1) Adult HIV Therapeutics Strategy Network, 2) the Vaccines to Prevent HIV Network, 3) the Integrated HIV Prevention Strategies Network, and 4) Bidirectional engagement of the relevant and at risk HIV-infected/impacted communities with the CCTU clinical researchers. The CCTU is well positioned to reach diverse populations and contribute significantly to the NIAID research agenda.

家长奖项目概要 芝加哥临床试验单位 (CCTU) 是由五个临床研究中心 (CRS) 组成的联盟， 解决 NIAID 的三个优先临床研究领域：1) 成人 HIV 治疗策略，包括 HIV 肝炎和结核病的治愈​​、非感染性合并症以及感染性合并症； 2）疫苗 预防艾滋病毒； 3) 综合艾滋病毒预防策略。 CCTU 由五位经验丰富且 具有科学生产力的 CRS，在开发、实施和适应临床方面具有独特的地位 NIAID 临床研究优先领域的研究重点。 CCTU 拥有良好的记录，并将 通过与各种高危人群和受艾滋病毒影响的人群积极接触，继续保持生产力 社区、参与高影响力、开创性的临床研究、有效管理 对临床活动、实验室和药房的资源和关键绩效监督。中央工会 包括长期有效参与其中三项研究的 CRS 和人员 网络；第四个——抗菌素耐药性——成为这个联盟中的一个新网络。 CRS 及其 网络附属机构包括：西北大学（成人艾滋病毒治疗策略）；伊利诺伊大学 芝加哥（预防艾滋病毒疫苗、艾滋病毒综合预防）、拉什大学（成人艾滋病毒治疗 策略）、芝加哥大学（综合艾滋病毒预防策略）和三一健康与保健中心 （成人艾滋病毒治疗策略）。其中四个 CRS 位于芝加哥，这是一个民族和种族多元化的城市 城市面积 950 万人口，是美国第三大都市区，也是美国最大的都市区之一 主要城市艾滋病毒中心。该提案的目的是：开发、实施和适应 1) 成人艾滋病治疗策略网络，2) 预防疫苗的临床研究计划 HIV 网络，3) HIV 综合预防策略网络，以及 4) 与 CCTU 临床研究人员一起帮助相关和面临风险的 HIV 感染/受影响社区。 CCTU 很好 旨在接触不同人群并为 NIAID 研究议程做出重大贡献。