Ethiopia-Emory TB Research Training Program

埃塞俄比亚-埃默里结核病研究培训计划

• 批准号: 10542772
• 负责人: HENRY M BLUMBERG
• 金额: $ 29.6万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-02 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10542772
• 关键词: Africa; Award; Cause of Death; Cessation of life; Collaborations; Country; Diagnostic; Drug resistance in tuberculosis; Ethiopia; Ethiopian; Faculty; Funding; Goals; Grant; HIV/TB; Health; Health Priorities; Health Professional; Human Resources; Infectious Agent; Institution; International; Knowledge; Leadership; Learning; Mentors; Mentorship; Multidrug-Resistant Tuberculosis; Peer Review; Public Health; Publications; Research; Research Infrastructure; Research Institute; Research Personnel; Research Training; Science; Scientist; Time; Training; Training Activity; Training Programs; Travel; Tuberculosis; Universities; Vaccines; Woman; World Health Organization; improved; innovation; novel therapeutics; public health emergency; skills; success; tool

Tuberculosis (TB) is now the leading cause of death due to a single infectious agent globally. TB remains a public health emergency in Ethiopia, the country with the highest number of TB-related deaths in Africa. Ethiopia is one of only 14 countries worldwide on all three World Health Organization (WHO) “high burden countries” lists for TB, multidrug resistant (MDR)-TB, and TB/HIV. In order to meet the ambitious WHO End TB Strategy goals for 2035 and enhance TB control in Ethiopia and globally, new tools are urgently needed, including new drugs, improved diagnostics and an effective vaccine, as well as better implementation of existing tools. A major barrier to improved research, treatment and control of TB in Ethiopia is the scarcity of Ethiopian scientists and health professionals with the relevant research knowledge and expertise to carry out internationally recognized research. This renewal application for the “Ethiopia-Emory TB Research Training Program (EETB-RTP)” builds upon the successes and lessons learned during the first 5-year cycle of funding. During that time, we have provided long-term research training to 19 Ethiopian trainees and 2 medium-term trainees. Collectively, these trainees have had 62 TB-related peer review publications, and 8 trainees received competitive externally funded grants as PI (totaling $815,801); in addition, 10 trainees received 14 competitive travel awards ($50,320). In the next cycle of the EETB-RTP, we propose to train an additional 17 long-term trainees who will significantly grow the number of well-trained Ethiopian TB investigators and contribute to developing and implementing new tools necessary for TB control. Our application benefits from a successful partnership between Emory University in Atlanta and three Ethiopian institutions in Addis Ababa including the Armauer-Hansen Research Institute (AHRI), an internationally recognized research institute; Addis Ababa University, the oldest and largest university in Ethiopia; and the Ethiopian Public Health Institute, part of the Ministry of Health (MOH). The EETB-RTP is led by dual PIs, Dr. Henry Blumberg (Emory) and Dr. Abraham Aseffa (AHRI) and includes outstanding collaborating faculty at the partner institutions. We propose an innovative didactic and mentored TB research training program focused on intensive in-country training, which will provide our Ethiopian trainees and their institutions with the skills, expertise, and additional capacity necessary to carry out internationally relevant TB-related research. The specific aims of our application include: 1) To continue to build human resource capacity and enhance the research infrastructure for robust TB-related research in Ethiopia; 2) To build relevant sustainable research capacity in Ethiopia by aligning EETB-RTP research training activities with the Ethiopian MOH priorities outlined in the “National Plan for Tuberculosis Research in Ethiopia (2017-2022)”; 3) To build research capacity by providing mentorship, leadership, and team science training; and 4) To enhance the diversity of Ethiopian investigators, with a concerted focus of increasing the number of women trained in TB research.

结核病（TB）现在是全球单一传染剂导致死亡的主要原因。结核病仍然是一个 埃塞俄比亚的公共卫生紧急情况，非洲与结核病相关的死亡人数最多的国家。 埃塞俄比亚是全球所有三个世界卫生组织（WHO）的全球仅有的14个国家之一 国家/地区的TB，多药耐药（MDR）-TB和TB/HIV的清单 2035年的战略目标并在埃塞俄比亚和全球增强结核病控制，迫切需要新工具， 包括新药，改进的诊断和有效的疫苗，以及更好地实施 现有工具。埃塞俄比亚改善研究，治疗和控制结核病的主要障碍是稀缺 埃塞俄比亚科学家和卫生专业人员具有相关研究知识和专家 国际公认的研究。此续签申请“埃塞俄比亚 - 埃马里结核病研究 培训计划（EETB-RTP）”建立在第一个5年周期中所学的成功和经验基础上 资金。在此期间，我们为19名埃塞俄比亚学员和2名的长期研究培训提供了长期研究培训 中期学员。总的来说，这些受训者有62个与TB相关的同行评审出版物，还有8个 受训人员以PI的价格获得了竞争性的外部资助赠款（总计815,801美元）；此外，有10名学员 获得了14个竞争性旅行奖（50,320美元）。在EETB-RTP的下一个周期中，我们建议训练 另外17名长期学员将大大增加训练有素的埃塞俄比亚结核病的数量 研究人员并为开发和实施结核病控制所需的新工具做出贡献。我们的 应用程序受益于亚特兰大埃默里大学与三个埃塞俄比亚的成功合作伙伴关系 亚的斯亚贝巴的机构，包括国际上的Armauer-Hansen研究所（AHRI） 公认的研究所；亚的斯亚贝巴大学，埃塞俄比亚最古老，最大的大学；和 埃塞俄比亚公共卫生研究所，卫生部（MOH）的一部分。 EETB-RTP由双PIS领导。 亨利·布鲁姆伯格（Henry Blumberg）（埃默里（Emory））和亚伯拉罕·阿萨菲（Ahri）博士（AHRI），包括杰出的合作教师 合作伙伴机构。我们提出了一个创新的教学和修改结核病研究培训计划 专注于密集的国内培训，这将为我们的埃塞俄比亚学员及其机构提供 进行与国际相关的结核病相关研究所需的技能，专业知识和额外能力。 我们应用程序的具体目的包括：1）继续建立人力资源能力并增强 埃塞俄比亚与TB相关研究的研究基础设施； 2）建立相关的可持续研究 通过将EETB-RTP研究培训活动与埃塞俄比亚MOH的优先级结合来使埃塞俄比亚的能力 在“埃塞俄比亚的结核病研究计划（2017-2022）”中概述； 3）建立研究 通过提供指导，领导力和团队科学培训的能力； 4）提高多样性 埃塞俄比亚的调查人员共同集中于增加在结核病研究中培训的妇女人数。