Georgia CTSA Research Supplement to Promote Diversity in Health-Related Research (Hernandez)

佐治亚州 CTSA 研究增刊促进健康相关研究的多样性 (Hernandez)

• 批准号: 9815750
• 负责人: HENRY M BLUMBERG
• 金额: $ 3.46万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-24 至 2021-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9815750
• 关键词: Address; Affect; Behavior; Clinical; Clinical Research; Clinical Sciences; Communities; Community Health Aides; Doctor of Philosophy; Ethnic group; Growth; Health; Hispanics; Immigrant; Intervention; Knowledge; Latina; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentorship; Methods; Mexican; Minority; Modeling; Prevention Research; Preventive; Principal Investigator; Research; Research Proposals; Role; Rural; Stress; System; Training; Translational Research; Vulnerable Populations; Woman; Work; anticancer research; base; cancer diagnosis; cancer health disparity; cancer prevention; career; cervical cancer prevention; contextual factors; experience; improved; innovation; outreach; parent grant; programs; public health relevance; racial and ethnic; rural area; rural underserved; trend

Program Director/Principal Investigator (Last, First, Middle): Taylor, W. Robert Project Summary/Abstract This diversity supplement builds upon the work of the Georgia Clinical and Translational Science Alliance (Georgia CTSA) (ULTR002378) parent grant by conducting translational research and better engaging rural and underserved Georgia Latinas in cervical cancer prevention, and participation in cancer clinical research. Latina women are disproportionately impacted by cervical cancer in comparison to women from other racial/ethnic groups. In the state of Georgia, this national trend remains as Latinas are disproportionately affected by higher rates of cervical cancer diagnoses compared to non-Latina black and white women. Although studies have identified facilitators to cervical cancer prevention among Latinas, they are narrow in scope and don't address Latinas residing in rural areas and the boarder contextual factors that may prohibit women from participating in prevention and clinical research. Using community engaged approaches applied through a minority stress framework, the objective of this research proposal is to identify and improve our understanding of the facilitators and barriers to cervical cancer prevention, and participation in cancer clinical research among rural Mexican immigrant Latinas in Georgia. Using a mixed-methods approach, the specific aims include: Aim 1a: To identify the facilitators and barriers of cervical cancer prevention methods among rural Latina women in Georgia; Aim1b: To investigate the role of promotoras (community health workers) and other community-based, cancer prevention opportunities and outreach strategies to decrease cervical cancer disparities; and Aim 2: To assess factors associated with Latina participation in clinical cervical cancer research. Hypothesis: Immigrant related minority stress factors will significantly decrease the likelihood of preventive behaviors, and participation in clinical research among rural Latina immigrants. This study is significant because Latina women simultaneously experience the greatest burden of cervical cancer health disparities and are the fastest growing major demographic in the U.S, thus this growth may exacerbate the burden of cervical cancer. The research is innovative because it: (1) focuses on a largely rural, underserved, vulnerable population with unique and specific needs; (2) uses the Minority Stress Model that has not being applied in cancer research; and (3) engages the community as a part of the interdisciplinary team. Research findings will be used to inform to inform community and system-level approaches to address a persistent disparity. OMB No. 0925-0001/0002 (Rev. 01/18 Approved Through 03/31/2020) Page Continuation Format Page

项目总监/首席研究员（最后，第一，中间）：泰勒（W. Robert） 项目摘要/摘要 这种多样性补充是基于佐治亚州临床和转化科学的工作 联盟（Georgia CTSA）（Ultr002378）父母赠款通过进行翻译研究和更好 吸引农村和服务不足的佐治亚州拉丁裔预防宫颈癌，并参与 癌症临床研究。拉丁女性受到宫颈癌的影响不成比例 与其他种族/族裔群体的妇女进行比较。在佐治亚州，这种国家趋势 保留为拉丁裔受到较高的宫颈癌诊断率的影响不成比例 与非拉丁裔黑人和白人妇女相比。尽管研究已经确定了促进者 在拉丁裔中预防宫颈癌，它们的范围狭窄，不解决拉丁裔 居住在农村地区和寄宿生的背景因素，可能禁止妇女参加 在预防和临床研究中。使用通过少数派应用的社区参与方法 压力框架是该研究建议的目的是识别和提高我们的理解 促进者和预防宫颈癌的障碍以及参与癌症的临床 佐治亚州农村墨西哥移民拉丁裔的研究。使用混合方法方法， 具体目的包括：目标1A：确定预防宫颈癌的促进因子和障碍 佐治亚州拉丁美洲妇女的方法； AIM1B：调查促销的作用 （社区卫生工作者）和其他基于社区的癌症预防机会以及 外展策略减少宫颈癌差异；目标2：评估相关因素 随着拉丁裔参与临床宫颈癌研究。假设：与移民相关的少数民族 压力因素将显着降低预防行为的可能性，并参与 农村拉丁裔移民的临床研究。这项研究很重要，因为拉丁女性 同时承受着宫颈癌健康差异的最大负担，并且是 在美国，增长最快的主要人群，因此这种增长可能会加剧 宫颈癌。这项研究具有创新性，因为它：（1）专注于农村，服务不足， 有独特和特定需求的脆弱人群； （2）使用没有的少数压力模型 应用于癌症研究； （3）将社区作为跨学科的一部分参与 团队。研究发现将用于告知社区和系统级别的方法 解决持续的差异。 OMB No. 0925-0001/0002（修订版01/18通过03/31/2020批准）页面延续格式页面