mDOT Administrative Core
mDOT 管理核心
基本信息
- 批准号:10541802
- 负责人:
- 金额:$ 44.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-15 至 2025-11-30
- 项目状态:未结题
- 来源:
- 关键词:AdoptionAdvisory CommitteesBiomedical ResearchBusinessesCellular PhoneChronic DiseaseCollaborationsCommunicationCommunitiesCompanionsDevelopmentEngineeringEnsureFeedbackFundingGeographyGoalsHealthHealthcareIndividualInfrastructureInstitutionInterventionLeadLeadershipMarketingMeasurableMeasuresMedicalMedicineMethodsMonitorNatureOutcomePatientsPoliciesPostdoctoral FellowPrincipal InvestigatorProceduresProductivityQualifyingResearchResearch PersonnelResearch Project GrantsResourcesRoleRunningScienceScientistSecureServicesSoftware EngineeringStructureStudentsSystemTechnologyTrainingTranslationsUnited States National Institutes of HealthUniversitiesWorkbiopsychosocialdata managementdata to knowledgeexperiencehealthy lifestyleimprovedmHealthmembermobile sensormultidisciplinarymultiple chronic conditionsopen sourceoperationorganizational structureoutreachpreventprogramspublic health relevancerecruitsoftware developmentsuccesstechnological innovationtechnology research and developmenttoolvirtualwearable device
项目摘要
Principal Investigator: Kumar, Santosh
mDOT – Administration Core
Abstract:
The mHealth Center for Discovery, Optimization & Translation of Temporally-Precise Interventions (the mDOT
Center) will enable a new paradigm of temporally-precise medicine to maintain health and manage the growing
burden of chronic diseases. The mDOT Center will develop and disseminate the methods, tools, and
infrastructure necessary for researchers to pursue the discovery, optimization and translation of temporally-
precise mHealth interventions. Such interventions, when dynamically personalized to the moment-to-moment
biopsychosocial-environmental context of each individual, will precipitate a much-needed transformation in
healthcare by enabling patients to initiate and sustain the healthy lifestyle choices necessary for directly
managing, treating, and in some cases even preventing the development of medical conditions. Organized
around three Technology Research & Development (TR&D) projects, mDOT represents a unique national
resource that will develop multiple technological innovations and support their translation into research and
practice by the mHealth community in the form of easily deployable wearables, apps for wearables and
smartphones, and a companion mHealth cloud system, all open-source.
Given that the inherently transdisciplinary, team-based nature of mHealth research requires scientists to cross
disciplinary and institutional boundaries, administration and operation of a functional resource center in mHealth
technologies requires a collaborative culture, with a team-science approach, that is geographically dispersed yet
functional in a virtual setting. mDOT will utilize its established and highly successful infrastructure, adaptive
procedural acumen, widely visible dissemination platforms, and deeply-experienced team to develop
administrative and operational policies and procedures relevant to the running of a national resource center. The
Administration Core will look to not only enhance the research of the collaborative projects (CPs) and service
projects (SPs), but also to streamline communication and involvement with new research groups with little or no
technological expertise. To achieve its goals, mDOT will pursue the following activities. First, mDOT will leverage
an established organizing structure and managerial practice to facilitate coordination, communication, and
collaboration among the team, CPs, SPs, and greater research community. Secondly, mDOT will establish
operational procedures that allows for successful work with the CPs and SPs – this includes mechanisms to
receive, vet, and approve the use of resources and devising criteria to prioritize the selection of other qualified
CP/SP candidates. Third, mDOT will recruit eminent scholars and nationally recognized thought leaders to serve
on a diverse external advisory committee (EAC) tasked with providing feedback and guidance on the mDOT
research agenda. Fourth, mDOT will secure and leverage institutional support that accommodates and sets up
the Center for success in achieving the research goals put forth by the investigating team. Finally, the
Administration Core will develop measurable metrics to monitor, assess, and evaluate the quality and utility of
mDOT technologies while taking a customer service approach that is adaptive to feedback and responsive to
the mHealth research community at large.
1
首席研究员:库马尔,桑托什
mDOT – 管理核心
抽象的:
时间精确干预措施的发现、优化和转化移动医疗中心 (mDOT
中心)将实现时间精确医学的新范式,以维持健康并管理不断增长的疾病
mDOT 中心将开发和传播方法、工具和方法。
研究人员寻求发现、优化和翻译时间所需的基础设施
精确的移动医疗干预措施,实时动态个性化。
每个人的生物心理社会环境背景,将促成急需的转变
通过使患者能够启动并维持直接健康所需的健康生活方式选择来实现医疗保健
有组织地管理、治疗,在某些情况下甚至预防疾病的发展。
mDOT 围绕三个技术研发 (TR&D) 项目代表了独特的国家
将开发多种技术创新并支持其转化为研究和成果的资源
移动医疗社区以易于部署的可穿戴设备、可穿戴设备应用程序的形式进行实践
智能手机和配套的 mHealth 云系统,全部开源。
鉴于移动医疗研究本质上是跨学科、基于团队的性质,要求科学家跨学科
移动医疗功能资源中心的学科和机构边界、管理和运营
技术需要一种协作文化,采用团队科学方法,这种文化在地理上分散但
mDOT 将利用其已建立且非常成功的自适应基础设施。
程序敏锐、广泛可见的传播平台以及经验丰富的开发团队
与国家资源中心运营相关的行政和运营政策及程序。
管理核心不仅致力于加强合作项目(CP)的研究和服务
项目(SP),而且还可以简化与新研究小组的沟通和参与,而这些研究小组几乎没有或根本没有
为了实现其目标,mDOT 将开展以下活动。
已建立的组织结构和管理实践,以促进协调、沟通和
其次,mDOT 将建立团队、CP、SP 和更大的研究社区之间的协作。
允许与 CP 和 SP 成功合作的操作程序 – 这包括以下机制:
接收、审查和批准资源的使用,并制定标准来优先选择其他合格的人员
第三,mDOT将招募知名学者和国家认可的思想领袖来服务。
多元化的外部咨询委员会 (EAC) 负责提供有关 mDOT 的反馈和指导
第四,mDOT 将确保并利用机构支持来容纳和建立研究议程。
中心成功实现了调查小组提出的研究目标。
管理核心将开发可衡量的指标来监控、评估和评价信息的质量和效用
mDOT 技术,同时采用适应反馈和响应的客户服务方法
整个移动医疗研究界。
1
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Santosh Kumar其他文献
Santosh Kumar的其他文献
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{{ truncateString('Santosh Kumar', 18)}}的其他基金
Extracellular vesicles-based drug delivery of antiretroviral regimen to target CNS HIV reservoirs
基于细胞外囊泡的抗逆转录病毒治疗方案的药物递送以靶向 CNS HIV 储存库
- 批准号:
10448467 - 财政年份:2021
- 资助金额:
$ 44.8万 - 项目类别:
Extracellular vesicles-based drug delivery of antiretroviral regimen to target CNS HIV reservoirs
基于细胞外囊泡的抗逆转录病毒治疗方案的药物递送以靶向 CNS HIV 储存库
- 批准号:
10252514 - 财政年份:2021
- 资助金额:
$ 44.8万 - 项目类别:
mHealth Center for Discovery, Optimization, and Translation of Temporally-Precise Interventions (mDOT)
时间精确干预措施的发现、优化和转化移动医疗中心 (mDOT)
- 批准号:
10541801 - 财政年份:2020
- 资助金额:
$ 44.8万 - 项目类别:
SUMO2-p66shc axis in vascular endothelial dysfunction and atherosclerosis
SUMO2-p66shc 轴在血管内皮功能障碍和动脉粥样硬化中的作用
- 批准号:
10363680 - 财政年份:2020
- 资助金额:
$ 44.8万 - 项目类别:
SUMO2-p66shc axis in vascular endothelial dysfunction and atherosclerosis
SUMO2-p66shc 轴在血管内皮功能障碍和动脉粥样硬化中的作用
- 批准号:
10577729 - 财政年份:2020
- 资助金额:
$ 44.8万 - 项目类别:
mHealth Center for Discovery, Optimization, and Translation of Temporally-Precise Interventions (mDOT)
时间精确干预措施的发现、优化和转化移动医疗中心 (mDOT)
- 批准号:
10025130 - 财政年份:2020
- 资助金额:
$ 44.8万 - 项目类别:
Targeted Nano-Chemosensitization of Breast Cancers
乳腺癌的靶向纳米化疗增敏
- 批准号:
9230196 - 财政年份:2017
- 资助金额:
$ 44.8万 - 项目类别:
Exosomes in tobacco-and HIV-mediated neurotoxcity
烟草和艾滋病毒介导的神经毒性中的外泌体
- 批准号:
9174185 - 财政年份:2016
- 资助金额:
$ 44.8万 - 项目类别:
Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K) - OVERALL
移动传感器数据到知识 (MD2K) 卓越中心 - 总体
- 批准号:
9087238 - 财政年份:2014
- 资助金额:
$ 44.8万 - 项目类别:
Center of Excellence for Mobile Sensor Data-to-Knowledge (MD2K) - OVERALL
移动传感器数据到知识 (MD2K) 卓越中心 - 总体
- 批准号:
8935797 - 财政年份:2014
- 资助金额:
$ 44.8万 - 项目类别:
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