RFA-CK-22-003, Emerging Infections Sentinel Networks (EISN) Research - 2022

RFA-CK-22-003，新发感染哨兵网络 (EISN) 研究 - 2022 年

• 批准号: 10516881
• 负责人: DAVID ANDREW TALAN
• 金额: $ 30万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-01 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10516881
• 关键词: RFA; CK; 22; 003; Emerging

Project Summary In 1995, following the Institute of Medicine’s report, “Emerging Infections,” and in response to the CDC’s strategic plan to enhance surveillance, EMERGEncy ID NET was established. EMERGEncy ID NET's goal was to address the threat of emerging infectious diseases by assessing disease prevalence, risk factors, and management practices for acute presentations from the community among a diverse and underserved population of patients presenting to US emergency departments (EDs). A CDC cooperative grant has funded the network for the last 25 years. Due to the ability to prospectively collect clinical data and specimens for on-site laboratory analysis 24/7 from acutely ill patients from the community, EMERGEncy ID NET has been able to produce translational research that has impacted physician practices and informed public health policy. The research network demonstrated its capability to successfully address an urgent public health threat during the COVID-19 pandemic by rapidly implementing 20-site and 16-site public health surveillance projects of ED patient care-related infection risk and vaccine effectiveness among frontline health care personnel. Numerous peer-reviewed publications have resulted from EMERGEncy ID NET research, including in high-impact journals such as The New England Journal of Medicine, the Journal of the American Medical Association, Clinical Infectious Diseases, Emerging Infectious Diseases, and Annals of Emergency Medicine. Aims of EMERGEncy ID NET for the next 5 years are to: 1) identify emerging infections and risk factors for these conditions affecting US ED patients, including among underserved groups; 2) leverage EMERGEncy ID NET’s findings to create new collaborations to develop and improve diagnostic tests, treatments, and vaccines; and 3) disseminate results at national medical conferences, in high-impact journals, and on infectious diseases, public health, and emergency medicine social media outlets to inform treatment and public health policy, and educate the public. Support of EMERGEncy ID NET for the next 5 years will ensure that the network can continue to answer new questions about emerging infections and related areas of high public health priority.

项目摘要 1995年，根据医学研究所的报告“新兴感染”，并回应 疾病预防控制中心提高监视的战略计划，紧急ID网是 已确立的。紧急ID网的目标是应对新兴传染性的威胁 通过评估疾病患病率，危险因素和急性管理实践的疾病 在潜水员和服务不足的患者中的社区演讲 向美国急诊部门（EDS）介绍。疾病预防控制中心合作赠款已资助 网络过去25年。由于能够收集临床数据和 来自社区急性病患者的现场实验室分析标本24/7， 紧急ID网已经能够进行影响的转化研究 实践和知情的公共卫生政策。研究网络证明了它的 在COVID-19大流行期间，能够成功解决公共卫生威胁的能力 通过快速实施ED患者的20个站点和16个地点的公共卫生监视项目 一线保健人员之间与护理相关的感染风险和疫苗有效性。 众多同行评审的出版物是由紧急ID NET研究引起的 包括《新英格兰医学杂志》等高影响期刊，《杂志》 美国医学协会，临床传染病，新兴的传染病， 和急诊医学年鉴。 接下来的5年的紧急ID网的目标是：1）确定新兴感染 以及影响美国ED患者的这些条件的风险因素，包括服务不足 群体； 2）利用紧急ID网的调查结果创建新的合作，以开发和 改善诊断测试，治疗和疫苗； 3）在国家国家传播结果 医疗会议，高影响期刊，感染疾病，公共卫生和 急诊医学社交媒体向治疗和公共卫生政策提供信息，以及 教育公众。接下来5年的紧急ID网络的支持将确保 网络可以继续回答有关新兴感染和相关领域的新问题 高公共卫生优先事项。