HoloSurge: Multimodal 3D Holographic tool and real-time Guidance System with point-of-care diagnostics for surgical planning and interventions on liver and pancreatic cancers

HoloSurge：多模态 3D 全息工具和实时指导系统，具有护理点诊断功能，可用于肝癌和胰腺癌的手术规划和干预

• 批准号: 10103131
• 金额: $ 137.99万
• 依托单位: UNIVERSITY OF LEEDS
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10103131
• 关键词: HoloSurge; Multimodal; 3D; Holographic; tool

Perioperative care is an intricate processthat encompasses 1) preoperative evaluation,surgical planning and preparation; 2) intraoperative procedure; and 3) postoperative management. Perioperative care depends on clinical decision-making, a continuous process that involves many healthcare professionals (incl. radiologists, surgeons, anaesthesiologists, nurses, and others) who – based on the best available evidence, clinical experience, and the patient's individual circumstances – make informed decisions on the best course of action. Even though advancementsin medical imaging modalities(CT, MRI, ultrasound) have greatly improved surgical outcomes, their interpretation towards deciding a specific course of action remains subjective. In addition, these modalities have several limitations when used alone (e.g., missed lesions; cannot provide a 3D visualization of key structures such as vessels), ultimately failing to provide a full picture of the patient’s anatomy that is shared and unambiguously understood by all in the assigned team. Due to these limitations, there are often suboptimal decisions that add to a cumulative risk of surgical complications in perioperative care. HoloSurge is a joint undertaking that brings European scientists and clinicians from high-tech companies, clinical centres, and research institutions in a consortium to deploy an innovative AI-based medical system that: i) enables automatic fusion and segmentation of state-of-the-art imaging modalities for interactive 3D holographic visualization of patients’ organs; ii) provides real-time surgical navigation; and iii) allows real-time cell-level cancer diagnostics. The solution will provide surgical teams with an unmatched holistic view of the patient’s anatomy and pathology in real-time at point of care, before and during surgery. This innovation will be validated for cancer interventions, while creating a trail of better-informed perioperative decision-making that can save countless lives

围手术期护理是一个复杂的过程，包括 1) 术前评估、手术计划和准备；2) 术中程序；3) 术后管理取决于临床决策，这是一个涉及许多医疗保健专业人员（包括放射科医生）的持续过程。尽管医学不断进步，但根据现有的最佳证据、临床经验和患者的个人情况，他们仍能做出明智的决定。成像方式（CT、MRI、超声）极大地改善了手术结果，但它们对决定具体行动方案的解释仍然是主观的。此外，这些方式单独使用时有一些局限性（例如，遗漏病变；无法提供 3D 可视化）。由于这些限制，通常会出现次优的决策，从而增加手术并发症的累积风险。在HoloSurge 是一项联合事业，由来自高科技公司、临床中心和研究机构的欧洲科学家和先驱组成一个联盟，部署基于人工智能的创新医疗系统，该系统：i）实现状态的自动融合和分割。用于患者器官的交互式 3D 全息可视化的最先进的成像模式；ii) 提供实时手术导航；以及 iii) 允许实时细胞级癌症诊断。在护理点、术前和术中实时获得无与伦比的患者解剖学和病理学整体视图这一创新将在癌症干预方面得到验证，同时创建一系列更明智的围手术期决策，可以挽救无数生命。