New Electrodes for Enabling Inclusive EEG Monitoring in Black Populations

新电极可实现黑人群体的包容性脑电图监测

基本信息

批准号：
10484809
负责人：
Jasmine Kwasa
金额：
$ 12.78万
依托单位：
PRECISION NEUROSCOPICS, INC
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10484809
关键词：
American Attention Awareness Black Populations Black race Brain Diseases Brain Injuries Child Clinic Clinical Clinical Research Collaborations Coma Communities Data Diagnosis Diagnostic Equipment Disease Down Syndrome Electrodes Electroencephalography Ensure Environment Epilepsy Exclusion Criteria Gold Hair Healthcare Hour Individual Industry Injury Intervention Laws Lead Medical Medical center Modality Monitor Neurosciences Noise Participant Patients Pediatric Hospitals Performance Policies Population Porifera Positioning Attribute Procedures Quality of Care Questionnaires Research Research Personnel Scalp structure Signal Transduction Skin Stroke System Techniques Testing Time United States National Institutes of Health United States Public Health Service Universities Work autism spectrum disorder black patient comorbidity density design electric impedance experience implicit bias improved innovation multidisciplinary nervous system disorder next generation novel relating to nervous system response standard of care success supportive environment treatment disparity

项目摘要

Electroencephalography (EEG) -- a neural sensing modality essential for diagnosis of epilepsy, stroke, brain injuries and other neurological disorders -- is not accessible to individuals with coarse and curly hair common in Black populations. The springiness of these hair-types makes it difficult to maintain a good electrodes-scalp contact. Consequently, Black patients are denied the same quality of care as others. Our team has designed the first electrodes -- Sevo electrodes1, and complementary hair-braiding techniques -- that work with these hair-types. In the proposed work, Precision Neuroscopics will rigorously quantify improvement in EEG metrics obtained using Sevo electrodes in clinical and research lab settings, as well as obtain new designs that broaden the applicability and market of Sevo. Aim 1 will test Sevo electrodes in a) clinical setting, comparing with clinical standard systems and electrodes; and b) neuroscience lab setting, comparing with state-of-the-art systems used in neuroscience labs. Aim 2 will broaden the applicability and the market for Sevo by designing i) braid-free electrodes; ii) embedding novel conductive sponge electrodes to obtain electrodes that are quick-apply and yet can be used for a long time; iii) electrodes designed high-density EEG installation. By testing rigorously in a clinical setting, we test our electrodes on a relevant population, namely, children suffering from epilepsy. While our electrodes will help all patients and participants with this hair-type, they will be of even greater help for patients with Down’s syndrome and autism spectrum, who find it difficult to have EEG electrodes applied on their scalp, a difficulty compounded for Black patients suffering from these disorders. The project can thus support the NIH INCLUDE initiative (https://www.nih.gov/include-project) specific to Down’s syndrome patients, and broadly, enable inclusive NIH studies as required by federal law (Public Health Service Act sec. 492B, 42 USC 289a-2) and NIH policy.

脑电图（EEG） - 诊断癫痫，中风，大脑必不可少的神经灵敏度方式损伤和其他神经系统疾病 - 粗毛和卷发常见的人无法使用在黑人人群中。这些接发的弹性使保持良好的电子式尺度很难接触。因此，黑人患者被剥夺了与其他人相同的护理质量。我们的团队设计了第一个电子 - Sevo Electrodes1和互补的发质技术 - 与这些技术一起使用发型。在拟议的工作中，精度神经镜检查将严格量化脑电图的改善在临床和研究实验室环境中使用SEVO电极获得的指标，并获得了新设计扩大了Sevo的适用性和市场。 AIM 1将在A）临床环境中测试Sevo电极，与临床标准系统和电子； b）神经科学实验室设置，与神经科学中使用的最新系统相比实验室。 AIM 2通过设计i）无辫子电极来扩大SEVO的适用性和市场； ii）嵌入新型的导电赞助商电子设备以获取快速应用的电子设备，却可以使用许久; iii）电极设计了高密度的EEG安装。通过在临床环境中严格测试，我们在相关人群上测试电极，即患有癫痫病的孩子。虽然我们的电极将帮助所有患者和参与者使用这种发型，但对于唐氏综合症和自闭症谱系的患者，他们将为他们提供更大的帮助，他们发现很难将脑电电极应用于头皮上，这是黑人患者的难度疾病。因此，该项目可以支持NIH包括倡议（https://www.nih.gov/include-project）特定于唐氏综合症患者，并且广泛地启用了联邦法律的包容性NIH研究（公共卫生服务法第492B条，第42条USC 289A-2）和NIH政策。