Coordination Core

协调核心

基本信息

批准号：
10480793
负责人：
RICHARD M CAPRIOLI
金额：
$ 8.58万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-30 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10480793
关键词：
3-Dimensional Achievement Atlases Biological Biomedical Research Budgets Collaborations Communication Communities Data Data Analyses Eye Foundations Freezing Goals High Performance Computing Human Human BioMolecular Atlas Program Imaging technology Infrastructure Laboratories Leadership Manuscripts Mass Spectrum Analysis Mining Mission Molecular Multimodal Imaging Organ Pancreas Physicians Procedures Protocols documentation Publications Publishing Reporting Research Research Activity Research Personnel Resources Role Sampling Scientific Evaluation Scientist Site Specimen Time Tissue Banks Tissue atlas Tissues Travel United States National Institutes of Health Universities Visualization Work complex data data exchange data management data mining data sharing design development policy experience flexibility human tissue imaging facilities large scale data meetings member molecular imaging multidisciplinary multimodality operation professional atmosphere programs skills success tissue mapping tool

项目摘要

PROJECT SUMMARY – Coordination Core. The proposed multidisciplinary Eye and Pancreas Tissue Mapping Center (TMC) for the Human BioMolecular Atlas Program (HuBMAP) requires diverse proficiencies including (1) the biological expertise and infrastructure required for acquisition of normal human tissue, (2) the analytical skills to produce highly multiplexed multimodal molecular imaging data, (3) computational expertise in integrating and mining complex data, and (4) a track record in collaboration between the TMC components and other HuBMAP consortium members. The Coordination Core (CC) will be a key center of administration for the proposed Vanderbilt University Eye and Pancreas Tissue Mapping Center (TMC). The specific aims of the CC directly reflect its role to prioritize achievement of program milestones through effective leadership, sharing of data and samples, and communication with HuBMAP leadership as well as interaction among Consortium groups to provide a foundation of success for the Vanderbilt Eye and Pancreas TMC. Leadership for the proposed TMC include distinguished experts in their fields: Dr. Jeffrey Spraggins (MPI, BIOMIC Director, DAC Team Leader), Dr. Richard Caprioli (MPI, CC Team Leader), Dr. Alvin Powers (MPI, Pancreas OSP Team Leader), and Dr. Kevin Schey (MPI, Eye OSP co-Team Leader). These four have worked extensively together in rigorous and large-scale research programs, for which they have managed research activities, collaborations, and data coordination. To contribute productively to the HuBMAP consortium, the proposed Vanderbilt Eye and Pancreas TMC will share and accept protocols, samples, and data to promote and unify 3-D molecular atlas construction across the Consortium. The Vanderbilt team will follow and participate in the development of policies and procedures established by the Consortium, including those for data/specimen sharing and publications. The overall mission of the CC and for the proposed TMC is to successfully contribute to HuBMAP to establish 3-D molecular human tissue atlases that advance biomedical research.

项目摘要 - 协调核心。拟议的多学科眼睛和胰腺组织映射人类生物分子图集计划（Hubmap）的中心（TMC）需要潜水员的能力，包括（1）获得正常人体组织所需的生物学专业知识和基础设施，（2）分析技能为了产生高度多重的多模式分子成像数据，（3）整合和挖掘复杂数据，以及（4）TMC组件与其他Hubmap之间协作中的记录财团成员。协调核心（CC）将是拟议的关键管理中心范德比尔特大学的眼睛和胰腺组织映射中心（TMC）。 CC直接的具体目的反映出通过有效的领导，数据共享和样本，以及与Hubmap领导以及财团群体之间的互动与为Vanderbilt Eye和Pancreas TMC提供成功的基础。拟议的TMC的领导包括其领域的杰出专家：Jeffrey Spraggins博士（MPI，Biomic总监，DAC团队负责人）， Richard Caprioli博士（MPI，CC团队负责人），Alvin Powers博士（MPI，Pancreas OSP团队负责人）和博士 Kevin Schey（MPI，EOSP共同团队负责人）。这四个在严格和他们管理研究活动，协作和数据的大规模研究计划协调。为Hubmap联盟有效地贡献，拟议的范德比尔特眼胰腺TMC将共享并接受协议，样本和数据，以促进和统一3-D分子地图集整个财团的建设。范德比尔特团队将遵循并参与政策的制定和财团建立的程序，包括用于数据/标本共享和出版物的程序。这 CC和拟议的TMC的总体任务是成功地为HubMap贡献3-D 推进生物医学研究的分子人体组织图谱。