Career Enhancement Program

职业提升计划

• 批准号: 10478022
• 负责人: Simon N. Powell
• 金额: $ 8.66万
• 依托单位: SLOAN-KETTERING INST CAN RESEARCH
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-13 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10478022
• 关键词: Adjuvant; Breast; Breast Cancer Patient; Career Choice; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Continuity of Patient Care; DNA Repair; Defect; Development; Discipline; Disease; Disease Management; Doctor of Philosophy; Ensure; Environment; Faculty; Funding; Genetic; Genomic Instability; Goals; Grant; Immunotherapy; Individual; Institution; Investigation; Knowledge; Laboratories; Laboratory Research; Link; Malignant Neoplasms; Memorial Sloan-Kettering Cancer Center; Mentors; Mentorship; Metastatic breast cancer; Modeling; Oncology; Pathway interactions; Patient Care; Patients; Pattern; Physicians; Population; Population Sciences; Process; Research; Research Personnel; Research Project Grants; SECTM1 gene; Scientist; Source; Surgeon; Training; Translational Research; Translations; United States National Institutes of Health; Work; career; certificate program; clinical application; clinical investigation; comparative; design; experience; faculty mentor; individualized medicine; interest; investigator training; malignant breast neoplasm; member; programs; recruit; targeted agent; targeted treatment; translational cancer research; translational scientist; trend

CAREER ENHANCEMENT PROGRAM RESEARCH PLAN CEP Director: Simon Powell, MD PhD CEP Co-Director: Jorge Reis-Filho, MD PhD Abstract: The SPORE Career Enhancement Program (CEP) aims to prepare physicians and scientists for independent careers in translational research in breast cancer. Our goal is that investigators supported through this process will spend their professional lifetimes conducting translational research in breast cancer and become academic leaders in the field. Memorial Sloan Kettering Cancer Center (MSKCC) is ideally suited for this task, because of the scientific and clinical environment at our Manhattan campus and affiliated institutions, and our long tradition of training physicians and scientists of the highest quality. Our institutional environment includes numerous NIH training grants, including a K12 grant for translational science training, a T32 grant to train PhDs in translational research in Oncology, a Certificate Program in Clinical Investigation integrated with the Clinical and Translational Science Program at Weill Cornell, and a well-established junior faculty mentoring program. We plan to use the SPORE Career Enhancement funds over the next 5 years to enhance the existing formal mentoring programs. We will encourage more physician trainees to focus on translational research in breast cancer, in particular to leverage the emerging knowledge of DNA repair defects and specific patterns of genetic instability in breast cancers to deliver targeted treatments to individual breast cancer patients. We will strive to attract basic, translational and population scientists who are interested in devoting their careers to making discoveries that have a realistic potential to clinical applications. The specific aims of the MSKCC Breast SPORE Career Enhancement Program are to support the mentoring and research of junior faculty for careers in translational research in breast cancer, using a dual clinical and laboratory/population science mentorship model, and to recruit and mentor new junior faculty members to work in breast cancer translational research.

职业增强计划研究计划 CEP主任：西蒙·鲍威尔（Simon Powell），医学博士 CEP联合导演：Jorge Reis-Filho，医学博士 抽象的： 孢子职业增强计划（CEP）旨在为医生和科学家准备独立 乳腺癌转化研究的职业。我们的目标是调查人员在此过程中支持 将花费他们的职业生命来进行乳腺癌的转化研究并成为学术 该领域的领导者。纪念斯隆·克特林癌症中心（MSKCC）非常适合此任务，因为 我们曼哈顿校园和附属机构的科学和临床环境以及我们悠久的传统 培训医师和最高质量的科学家。我们的机构环境包括许多NIH 培训补助金，包括用于转化科学培训的K12赠款，T32赠款，用于培训PHD的翻译 肿瘤学研究，与临床和翻译集成的临床研究证书计划 威尔·康奈尔（Weill Cornell）的科学课程，以及一项良好的初级教师指导计划。我们计划使用 在未来5年内，孢子职业增强基金以增强现有的正式指导计划。 我们将鼓励更多的医师学员专注于乳腺癌的转化研究，特别是 利用乳房中DNA修复缺陷和遗传不稳定性的特定模式的新兴知识 癌症为个别乳腺癌患者提供有针对性的治疗。我们将努力吸引基本， 对奉献职业感兴趣的转化和人口科学家 具有临床应用的现实潜力。 MSKCC乳腺孢子职业的具体目的 增强计划是为了支持翻译职业的初级教师的指导和研究 乳腺癌研究，使用双重临床和实验室/人口科学指导模型，并 招募和导师新的初级教师从事乳腺癌转化研究。