Monitoring the hemodynamic response to therapy in diabetic retinopathy

监测糖尿病视网膜病变治疗的血流动力学反应

• 批准号: 10475230
• 负责人: Amani A Fawzi
• 金额: $ 44.69万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10475230
• 关键词: Address; Adult; Affect; Age; Aneurysm; Angiography; Area; Automation; Blindness; Blood; Blood Flow Velocity; Blood Vessels; Blood capillaries; Blood flow; Burn injury; Cell physiology; Clinical; Clinical Trials; Collaborations; Color; Complications of Diabetes Mellitus; Computer software; Coupled; Data; Development; Diabetes Mellitus; Diabetic Retinopathy; Disease; Extravasation; Eye; Functional disorder; Goals; Hemorrhage; Image; Imaging Techniques; Individual; Interruption; Knowledge; Lasers; Lateral; Lead; Light Coagulation; Liquid substance; Maps; Measurement; Measures; Medical; Microaneurysm; Monitor; Natural History; Nerve Degeneration; Ophthalmology; Optics; Outcome; Outcome Measure; Pathology; Patients; Performance; Perfusion; Peripheral; Pharmaceutical Preparations; Pharmacotherapy; Photography; Physiological; Resolution; Retina; Retinal Hemorrhage; Scanning; Speed; Surface; Technology; Testing; Thick; Time; Treatment outcome; Vascular Diseases; Vision; adaptive optics; adaptive optics scanning laser ophthalmoscopy; alternative treatment; angiogenesis; base; clinical development; cost; density; diabetic; endothelial repair; flexibility; hemodynamics; improved; insight; macula; macular edema; multimodality; non-invasive imaging; novel; novel therapeutics; optical imaging; preservation; proliferative diabetic retinopathy; quantitative imaging; response; retinal angiogenesis; retinal imaging; retinal ischemia; standard of care; success; therapy design; therapy outcome; time use; tool; treatment response

This proposal aims to study retinal blood flow, detected by non-invasive imaging, during medical treatments for diabetic retinopathy. Success of this proposal will lead to the development of non-invasive measurements that can guide clinicians as they manage patients with sight threatening complications of diabetic retinopathy.

该提案旨在研究在医学治疗期间通过非侵入性成像检测到的视网膜血流 糖尿病视网膜病变。该提案的成功将导致非侵入性测量的发展 可以指导临床医生治疗患有威胁视力的糖尿病视网膜病变并发症的患者。