FASEB SRC: Skeletal Muscle Stem Cells and Regeneration

FASEB SRC：骨骼肌干细胞和再生

基本信息

批准号：
10464291
负责人：
Addolorata Pisconti
金额：
$ 2.3万
依托单位：
FEDERATION OF AMER SOC FOR EXPER BIOLOGY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-06-01 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10464291
关键词：
Adult Aging American Animals Area Attention Biology Biomedical Engineering Career Choice Collaborations Communities Complex Data Development Disease Disease model Educational workshop Engineering Ensure Equilibrium Evaluation Exercise Faculty Fertilization Food Industry Fostering Future Gender Genus Mentha Geography Goals Growth Health Homeostasis Human Hypertrophy Individual Injections International Louisiana Meat Mentors Metabolism Minority Molecular Muscle Muscle function Muscle satellite cell Muscular Dystrophies Myopathy Natural regeneration Nervous system structure Neuromuscular Junction Organoids Participant Physiological Policies Property Recording of previous events Records Regenerative capacity Regulation Research Research Personnel Role Science Scientist Signal Transduction Skeletal Muscle Slide Societies Structure Surveys System Therapeutic Intervention Tissues Translating Underrepresented Minority Underrepresented Populations Woman Work base bone career career development career networking cell behavior collaborative environment experience graduate student insight interest meetings mid-career faculty muscle aging muscle engineering muscle regeneration novel posters professor programs regeneration following injury regenerative repaired satellite cell senescence stem cell biology stem cell niche stem cell self renewal stem cell therapy stem cells symposium targeted treatment therapeutic development tool unpublished works virtual

项目摘要

PROJECT SUMMARY This application seeks partial support for the upcoming Federation of American Societies of Experimental Biology (FASEB) conference entitled, "Skeletal Muscle Stem Cells and Regeneration", which will be held July 24-28th, 2022 in New Orleans, Louisiana. This will be the 11th edition of this conference focusing on adult skeletal muscle stem cells (MuSCs) and the 10th sponsored by FASEB. Based on attendance records from previous years, we expect approximately 175 attendees from around the world of whom ~50% are expected to be women and ~60% junior researchers. No other scientific meeting has a primary focus on MuSCs. The need for a conference with this focus is demonstrated by the steady increase in attendance since the meeting's inception and the consistently excellent post-meeting evaluations provided by meeting attendees. This meeting attracts all leading MuSC researchers from around the world, further demonstrating its value for established and future leaders in the field. The overall objectives of this biennial meeting include: 1) to provide a comprehensive analysis of recent discoveries in the field, with the goal of understanding the regulatory mechanisms controlling normal and abnormal functions of MuSCs in muscle homeostasis, regeneration, hypertrophy, aging, and myopathy; 2) to create and foster an interactive environment for the exchange of ideas and unpublished data, so as to hasten discoveries and facilitate new and existing collaborations; 3) to provide opportunities for junior investigators to present their work and network with senior investigators; and 4) to facilitate career development of women and other underrepresented groups by ensuring representation in all aspects of the conference program. Our keynote speaker will be Dr. Edward De Robertis, a pioneer in development and stem cell biology. Eight sessions are planned, presenting 48 speakers (24 invited speakers and at least 24 selected from submitted abstracts) at all career levels. Session topics include: (i) molecular regulation of MuSCs, (ii) stem cells and regeneration in diseased muscle, (iii) the MuSC niche and cell signaling, (iv) interaction of MuSCs with, and regeneration of, the MTJ and the NMJ, (v) dynamics of muscle regeneration, (vi) engineering and translating MuSCs, (vii) muscle homeostasis and regeneration in aging, (viii) Metabolism and exercise in muscle regeneration. Invited speakers have been selected for their scientific excellence, with particular attention to equal representation of women and minorities and geographical diversity. Speakers are explicitly required to present unpublished work, to ensure scientific discussion is at the forefront of the field. We will have four poster sessions, each preceded by a “posters blitz” where selected poster presenters will give a one-minute talk to highlight their work; career-oriented workshops and “meet-the-expert” breakfast and lunch sessions. This meeting will provide a forum to foster discussion and cross-fertilization from diverse areas of research, to advance our understanding of muscle regeneration and help in the development of therapeutics.

项目摘要该申请为即将到来的美国实验学会联合会寻求部分支持生物学（FASEB）会议标题为“骨骼肌干细胞和再生”，将于7月举行 24-28，2022年，路易斯安那州新奥尔良。骨骼肌干细胞（MUSC）和FaseB赞助的第10个。往几年，我们预计世界上约有175名参与者，预计约有50％妇女和约60％的初级研究人员都没有其他科学会议自从会议的稳定上升范围内，以这种重点的会议表明了这一重点的会议。本会会议的成立和始终如一的出色的邮政评估。吸引了来自世界各地的所有领先的MUSC研究人员，进一步证明了其对既定的价值和未来的领导者。这两年一次的会议的总体目标包括：1）对最近的全面分析该领域的发现，其目标是控制正常和正常的守法机制， MUSC在肌肉稳态，再生，肥大，衰老和肌病中的异常功能；创建并培养一个交换DDEA和未发表数据的互动环境，以加速发现并促进新的和现有的合作； 3）与高级调查员一起介绍工作和网络； 4）通过确保在会议计划的各个方面代表的其他定价群体不足的群体。我们的主题演讲者将是Edward de Robertis博士，这是八个开发和干细胞生物学的先驱。计划会议，展示48位发言人（24位受邀演讲者，至少有24位提交的演讲者摘要）在所有职业级别中。患病肌肉的再生，（iii）MUSC细胞和细胞信号传导，（iv）MUSC与和和和和和和和和和 MTJ和NMJ的再生，（V）肌肉再生动力学，（VI）工程和翻译 MUSC，（vii）肌肉稳态和衰老的再生，（VIII）代谢和运动再生。妇女和少数族裔和地理多样性的代表是明确的。目前未发表的工作以确保科学讨论是该领域的最前沿。会议，每个会议先于“海报闪电”，其中选定的海报演讲者将与突出他们的工作；这次会议将提供一个论坛，以促进各种研究的讨论和交叉利用，促进我们对肌肉再生的理解，并有助于疗法的发展。