Developing research leaders at the intersection of malnutrition and tuberculosis in Tanzania

培养坦桑尼亚营养不良和结核病交叉领域的研究领导者

• 批准号: 10461564
• 负责人: Scott K Heysell
• 金额: $ 25.03万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-03-01 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10461564
• 关键词: Africa; COVID-19; Caring; Categories; Cessation of life; Clinical Research; Communicable Diseases; Communication; Communities; Developing Countries; Diabetes Mellitus; Disease; Emerging Communicable Diseases; European; Faculty; Foundations; Funding; Grant; Growth; Health; Infectious Diseases Research; Infrastructure; International; Lead; Leadership; Malnutrition; Medical; Mentors; Needs Assessment; Policy Making; Postdoctoral Fellow; Poverty; Public Health; Reporting; Research; Research Institute; Research Training; Scientist; Structure; Tanzania; Testing; Training; Training Programs; Tuberculosis; United States National Institutes of Health; Universities; Virginia; World Health Organization; Writing; base; career; college; design; doctoral student; experience; global health; health equity; minority health; nutrition; post-doctoral training; skills; undergraduate student

PROJECT SUMMARY / ABSTRACT This application for a new Global Infectious Diseases Research Training program (GIDRTP) at the University of Virginia (UVA) extends decades of training global leaders in diseases of poverty and infectious diseases through cycles of support of International Training and Research in Emerging Infectious Diseases, Actions for Building Capacity, Minority Health International Research Training, and Fogarty GIDRTPs. These prior experiences provide lessons learned and tested mechanisms for developing trainees into independent public health scientists. Despite the prior focus on early stage trainees such as undergraduate, Masters or doctoral students, we have noted unique barriers in progression through postdoctoral training to research leadership in Tanzania. We performed a needs assessment among Tanzanian postdoctoral scientists in 2021 which confirmed this observation and outlined gaps and opportunities with which to structure a postdoctoral focused GIDRTP. UVA, the Division of Infectious Diseases and International Health, and the Center for Global Health Equity have been at the forefront of research and training in malnutrition and its infectious consequences for decades. In non- pandemic periods, tuberculosis (TB) is the leading killer from a curable infectious disease. COVID-19 has further disrupted TB care and is projected to increase deaths from TB by 20% over the next five years. Malnutrition, both undernutrition and poor nutrition leading to conditions such as diabetes mellitus, is the most important driver of TB disease globally. Therefore, this GIDRTP aims to strengthen existing educational and research linkages with the UVA and the Kilimanjaro Christian Medical University College/ Kilimanjaro Clinical Research Institute (KCMUCo/KCRI) in Tanzania, to support Tanzanian postdoctoral trainees' growth to research leaders working at the intersection of malnutrition and TB. We aim to train 6 postdoctoral scientists with 3 years of support each through an individualized research leadership plan based on the framework of the Path to Research Leadership in Africa Report (2020). In addition to matching postdoctoral fellows to Tanzanian and UVA mentors, the individualized research leadership plan will include assessment by Lead Educators and core programmatic faculty including a biostatistician to design personalized coursework and skills building toward the metric categories of research team management, communication, grant writing, professionalism and career trajectory. We will harness the current infrastructure of funding from the National Institutes of Health, Bill and Melinda Gates Foundation, European and Developing Countries Trials Partnership, World Health Organization and the Danish Ministry of Foreign Affairs for TB and malnutrition research in Tanzania, and we expect to launch the careers of junior scientists and content leaders that will compete for independent funding, set research agendas, make policy and benefit their communities in- line with the World Health Organization's End TB Strategy.

项目摘要 /摘要 该新的全球传染病研究培训计划（GIDRTP）的申请 弗吉尼亚州（UVA）扩展了数十年的培训全球领导者，以解决贫困和传染病疾病的疾病 支持新兴传染病的国际培训和研究的支持，建立行动 能力，少数族裔国际研究培训和Fogarty Gidrtps。这些先前的经历 提供经验教训和经过测试的机制，以将受训者发展为独立的公共卫生 科学家。尽管先前专注于早期学员，例如本科生，硕士或博士生，但 我们已经注意到，通过博士后培训对坦桑尼亚的研究领导力进行了独特的障碍。 我们在2021年对坦桑尼亚的博士后科学家进行了需求评估，这证实了这一点 观察并概述了构建以博士后为中心的GIDRTP的差距和机会。 UVA， 传染病和国际卫生和全球卫生公平中心的划分已经 在营养不良的研究和培训的最前沿及其几十年来的传染性后果。在非 - 大流行时期，结核病（TB）是可治愈的传染病的主要杀手。 COVID-19的进一步 TB护理中断，预计将在未来五年内将结核病的死亡人数增加20％。营养不良， 营养不良和导致糖尿病等疾病的营养不良，是最重要的驱动因素 全球结核病疾病。因此，该GIDRTP旨在加强现有的教育和研究联系 与UVA和Kilimanjaro基督教医科大学/乞力马扎罗州临床研究所 （KCMUCO/KCRI）在坦桑尼亚，以支持坦桑尼亚博士后学员的成长，以研究领导者 在营养不良和结核病的交集处。 我们的目标是通过个性化的研究培训6位博士后科学家3年的支持 基于非洲研究领导道路的框架的领导计划（2020年）。此外 为了使博士后研究员与坦桑尼亚和UVA导师相匹配，个性化的研究领导计划将 包括首席教育者和核心程序化教师的评估，包括生物统计学家设计 个性化课程和技能朝向研究团队管理的指标类别， 沟通，赠款写作，专业和职业轨迹。我们将利用当前的基础设施 美国国立卫生研究院，比尔和梅琳达·盖茨基金会，欧洲和发展中的资金 国家审判合作伙伴关系，世界卫生组织和丹麦外交部针对结核病和 坦桑尼亚的营养不良研究，我们希望启动初级科学家和内容领导者的职业 这将竞争独立资金，制定研究议程，使政策和使其社区受益 与世界卫生组织的结核结核病策略保持一致。