Translational Science Training to Reduce the Impact of Alcohol on HIV Infection

减少酒精对艾滋病毒感染影响的转化科学培训

• 批准号: 10457376
• 负责人: Robert L Cook
• 金额: $ 33.87万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-01 至 2023-08-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10457376
• 关键词: Alcohols; HIV Infections; Training; Translational Research

Creation of a new T32 program in Florida, focused on alcohol and HIV infection, will fulfill a significant need. The state of Florida currently ranks first in new HIV infections per year, second in total HIV/AIDS cases, and third in total US population. Alcohol consumption contributes to poor HIV outcomes and to ongoing HIV transmission, and the relationships between alcohol consumption and HIV can vary by age, gender, ethnicity, and sexual orientation. The University of Florida is an ideal location to host the proposed T32, not only due to its geographic location and access to diverse populations, but also due to our growing NIH-supported alcohol research and infrastructure. The overall objective of this T32 grant is to train and mentor the next generation of researchers who have the skills, knowledge and experience to improve health outcomes in those affected by alcohol and HIV. We need a research task force that is capable of developing and implementing alcohol intervention across diverse populations, who can use novel data systems and sources, and who seek to reduce comorbidities associated with aging. Thus, the specific aims of our training program are to a) deliver an academic curriculum, b) provide outstanding mentoring, c) ensure skills in communication of science, d) provide experience in team science, and e) maximize professionalism and ethical conduct of research. The training program will support up to four pre-doctoral and two post-doctoral trainees at any given time, and several potential candidates have already expressed interest. Trainees will be based in the following academic programs: Epidemiology, Biostatistics, Clinical and Health Psychology, Nursing Science, Health Education and Behavior, and/or the Interdisciplinary Program in Medicine. These programs represent a broad range of health- related disciplines, ensuring trainees will have state of the art training in team science. Our 18 faculty mentors span four colleges and eight departments at UF. Each bring unique skills and expertise related to alcohol and HIV. The training program will ensure appropriate depth in knowledge regarding alcohol, HIV, and three additional focus areas that represent areas of strength in ongoing research at UF: a) health behavior intervention science; b) epidemiology and data science; and c) cognitive science related to aging. The training program will be closely integrated with Southern HIV Alcohol Research Consortium (SHARC), which is supported by over $10 million in ongoing NIAAA funding through 2021. The T32 will be led by three MPIs who each have specific administrative roles, and who will obtain input from an Internal Steering Committee, an Advisory Council, and ongoing program evaluations. UF is an outstanding training environment with many supporting resources, including a pledge to provide an additional $500,000 in overall support to our specific training program. Ultimately, the impact of the training program will be judged by the long-term track record of trainees who complete the training program, which we will monitor over time.

在佛罗里达州创建一个新的T32计划，侧重于酒精和艾滋病毒感染，将满足大量需求。 目前，佛罗里达州每年在新的艾滋病毒感染中排名第一，在艾滋病毒/艾滋病案件中排名第二，而 美国总人口中的第三。饮酒会导致艾滋病毒不良结果和持续的艾滋病毒 传播以及饮酒与艾滋病毒之间的关系会因年龄，性别，种族而异， 和性取向。佛罗里达大学是主持拟议T32的理想场所，不仅是由于 它的地理位置位置和访问不同人群的机会，但也是由于我们不断增长的NIH饮酒 研究和基础设施。 T32赠款的总体目标是培训和指导下一代 具有技能，知识和经验的研究人员，以改善受人们影响的人的健康状况 酒精和艾滋病毒。我们需要一个能够开发和实施酒精的研究工作队 跨不同人群的干预，他们可以使用新颖的数据系统和来源，并寻求 减少与衰老相关的合并症。因此，我们培训计划的具体目的是a） 学术课程，b）提供出色的指导，c）确保科学交流的技能，d） 提供团队科学的经验，以及e）最大程度地提高专业精神和研究的道德行为。这 在任何给定时间 几位潜在的候选人已经表达了兴趣。学员将基于以下学术 计划：流行病学，生物统计学，临床和健康心理学，护理科学，健康教育和 行为和/或医学跨学科计划。这些计划代表了广泛的健康 - 相关学科，确保学员将接受团队科学领域的最新培训。我们的18位教师导师 在UF跨越四所大学和八个部门。每种都带来与酒精有关的独特技能和专业知识 艾滋病病毒。培训计划将确保适当的有关酒精，艾滋病毒和三个知识的知识深度 在UF正在进行的研究中代表力量领域的其他重点领域：a）健康行为 干预科学； b）流行病学和数据科学； c）与衰老有关的认知科学。培训 计划将与南方艾滋病毒研究联盟（Sharc）紧密整合， 到2021年，由超过1000万美元的NIAAA资金支持超过1000万美元。T32将由三名MPI领导 每个人都有特定的行政角色，谁将从内部指导委员会获得意见 咨询委员会和正在进行的计划评估。 UF是一个出色的培训环境 支持资源，包括保证为我们的具体提供额外的500,000美元的总体支持 培训计划。最终，培训计划的影响将由长期记录来判断 完成培训计划的学员，我们将随着时间的流逝进行监控。