Sustainable Bioproduction of Lactobionic Acid from Whey-Based Bioprocess and Expansion of Accessible Markets through Biotech Active Ingredients ("BIONICe")

通过乳清基生物工艺可持续生物生产乳糖酸，并通过生物技术活性成分（“BIONICe”）扩大可及市场

• 批准号: 10078512
• 金额: $ 38.88万
• 依托单位: ACTIVATEC LTD
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10078512
• 关键词: Sustainable; Bioproduction; Lactobionic; Acid; Whey

The project is focused on the use of true industrial waste streams, or the bio valorisation of low-value products derived from them. One example would be bio valorisation of whey, whey permeate, or whey derived lactose, which although produced in 180 to 190 million tonnes per annum from the manufacture of cheese and other dairy products, are still poorly exploited natural resources.The focus of this project is an accelerated development of a whey-based, sustainable bioprocess for the manufacture of lactobionic acid, a key, highly efficacious and desirable anti-ageing and moisturising cosmetic ingredient which also has applications in a range of other diverse markets such as Food/Pharma and the chemical industry. The project outcome will be a commercially relevant end-to­ end process ready for first tech transfer and initial manufacturing trials at a selected Toll manufacturing company.Targeting the environmentally sensitive manufacture of ingredients primarily for use in cosmetics and personal care and in particular for use in skincare permits Activatec to fully exploit the changing face of the cosmetics industry driven by the rapidly changing consumer trends towards 'organic'; 'natural' 'green' and 'environmentally sensitive' product labelling and the trending interest in 'fermented cosmetics'The manufacturing approach is simplistic, in line with reported non-commercial methods, but innovative in design which will permit successful commercial exploitation. The whole approach is designed for sustainability utilising environmentally benign manufacturing methods including those required for the downstream recovery and purification of the product. The technology is also expected to be flexible with the potential for cross-application for the manufacture of other related specific target products and derivatives.

该项目的重点是利用真正的工业废物流，或对由此产生的低价值产品进行生物增值，其中一个例子是乳清、渗透乳清或乳清衍生乳糖的生物增值，尽管这些产品是在 180 至 190 年生产的。每年来自奶酪和其他乳制品生产的数百万吨自然资源仍然没有得到充分利用。该项目的重点是加速开发基于乳清的可持续生物工艺，用于生产奶酪和其他乳制品。乳糖酸是一种关键、高效且理想的抗衰老和保湿化妆品成分，也可应用于食品/制药和化学工业等一系列其他不同市场。该项目的成果将是商业相关的端到端。最终流程已准备好在选定的拓领制造公司进行首次技术转让和初步制造试验。以主要用于化妆品和个人护理品，特别是用于护肤品的成分的环境敏感制造为目标，使Activatec能够充分利用消费者对“有机”、“绿色”和“环境敏感”产品标签的趋势迅速变化，以及对“发酵化妆品”的兴趣日益浓厚，化妆品行业的面貌正在发生变化。非商业方法，但设计创新，将允许成功的商业开发，整个方法旨在利用环境友好的制造方法（包括下游回收和纯化产品所需的方法）实现可持续发展。具有交叉应用制造其他相关特定目标产品和衍生物的潜力。