MGH Next Generation Physician-Scientist Through Stimulating Access to Research in Residency Program (MGH-Next Gen StARR)

MGH 下一代医师科学家通过促进住院医师研究项目 (MGH-Next Gen StARR)

• 批准号: 10441143
• 负责人: Jatin M Vyas
• 金额: $ 33.73万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10441143
• 关键词: Address; Area; Asthma; Atherosclerosis; Automobile Driving; Basic Science; Bioinformatics; Biology; Biomedical Research; Blood Vessels; Boston; Cardiac; Cardiovascular Diseases; Career Choice; Cause of Death; Chronic Obstructive Pulmonary Disease; Chronic lung disease; Clinic; Clinical; Clinical Medicine; Clinical Research; Clinical Skills; Communities; Conflict (Psychology); Coupled; Development; Development Plans; Educational process of instructing; Epidemiology; Faculty; Failure; Fostering; Frustration; Funding; General Hospitals; Genomics; Health; Health Care Research; Heart Diseases; Heart failure; Hematological Disease; Hospitalists; Human; Hypertension; Inpatients; Institutes; Institution; Intellectual Interest; Internist; Investigation; Knowledge; Laboratories; Leadership; Learning; Lung; Lung diseases; Massachusetts; Measures; Medical; Medical Education; Medical Students; Medicine; Mentors; Mentorship; Metabolic; Metabolic Diseases; Methodology; Modeling; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Outcome; Participant; Pathway interactions; Patient Care; Patients; Physicians; Play; Prevalence; Pulmonary Inflammation; Readiness; Regenerative Medicine; Research; Research Personnel; Research Project Grants; Residencies; Role; Science; Scientist; Source; Structure; Surgeon; Therapeutic; Time; Training; Translating; Work; apprenticeship; base; cardiometabolism; career; clinical investigation; design; experience; improved; innovation; interest; mortality; multidisciplinary; next generation; preservation; programs; research and development; role model; skill acquisition; statistics; stem cell biology; success; symposium; time use; translational approach; translational study

PROJECT SUMMARY Physician-scientists play a unique role in bridging the gap between basic science and clinicians through the identification of important clinical questions and translating results to improve patient care. Unfortunately, the physician-scientist workforce continues to diminish and contributes to negative, long-lasting consequences in biomedical research. Many residency programs focus heavily on acquiring medical knowledge as opposed to fostering intellectual curiosity and an introduction into the biomedical research field. In this proposal, we aim to enhance attractiveness and preparedness for a career as a physician-scientist during residency training. Furthering the diminishing interest in a career as a physician-scientist is the ability to identify an encouraging and successful mentor. There is a critical need for a renewed emphasis on established physician-scientists as role models to trainees. Cardiac biology, pulmonary inflammation and regenerative medicine are fundamental areas of science that greatly benefits from a robust physician-scientist workforce. We hypothesize that early and longitudinal mentorship combined with development of research and professional development skills in the areas of regenerative medicine, cardiac and pulmonary biology will make the physician-scientist career path attractive and sustainable. To this end, we propose the implementation of the Massachusetts General Hospital Next- Generation Physician-Scientist Through Stimulating Access to Research in Residency (MGH Next-Gen StARR) program. The program will train new physician-scientists throughout the biomedical research continuum who will promote new preventative and therapeutic measures for diseases of the heart, lungs, and blood. The MGH Next-Gen StARR program is centered around the following three objectives: [1] To foster the creation of important scientific contributions through strong, longitudinal mentorship with an emphasis on leadership essentials; [2] To develop sufficient basic laboratory and translational approaches necessary to conduct high- quality research in the areas of regenerative medicine, cardiometabolic and pulmonary biology; and [3] To formulate hypothesis-based research questions, development and execution of a research project, and effectively communicate the significance of their science. MGH Next-Gen StARR program will allow two residents from the Department of Medicine to conduct research for 12-24 months at MGH or the Broad Institute. The program will be led by Jatin M Vyas (Medicine), an Executive Steering Committee and External Advisory Board, along with 58 multidisciplinary and well-funded research preceptors. Together, these initiatives are designed to attract, train, and retain MDs in biomedical investigation in the areas of vascular biology and regenerative medicine at the most critical juncture of their career - residency training.

项目摘要 医师科学家在弥合基础科学和临床医生之间的差距方面发挥了独特的作用 确定重要的临床问题并翻译结果以改善患者护理。不幸的是， 医师科学家的劳动力继续减少，并导致负面的，持久的后果 生物医学研究。许多居住计划重点是获取医学知识，而不是 促进了智力的好奇心，并介绍了生物医学研究领域。在此提案中，我们的目标是 在居住培训期间，增强了作为医师科学家职业的吸引力和准备。 扩大作为医生科学家职业的兴趣减少的能力是确定令人鼓舞的能力 和成功的导师。迫切需要重新强调已建立的医师科学家作为 向学员的榜样。心脏生物学，肺部炎症和再生医学是基本的 科学领域大大受益于强大的医师科学家劳动力。我们假设这很早就 纵向指导与该领域的研究和专业发展技能的发展相结合 再生医学，心脏和肺部生物学将使医生科学家职业道路吸引人 和可持续。为此，我们提议下一家马萨诸塞州总医院的实施 - 通过刺激居住研究的访问（MGH下一代），生成医师科学家 Starr）程序。该计划将在整个生物医学研究中培训新的医师科学家 谁将促进心脏，肺部和血液疾病的新预防和治疗措施。这 MGH下一代Starr计划以以下三个目标为中心：[1]促进创建 重要的科学贡献通过强大的纵向指导，重点是领导 要点； [2]开发足够的基本实验室和翻译方法，以进行高 再生医学，心脏代谢和肺类生物学领域的质量研究；和[3] to 提出基于假设的研究问题，研究项目的开发和执行以及 有效地传达其科学的重要性。 MGH下一代Starr计划将允许两个居民 从医学系开始在MGH或Broad Institute进行12-24个月的研究。这 计划将由执行指导委员会和外部顾问委员会Jatin M Vyas（医学）领导 以及58个多学科且资助良好的研究受体。这些举措共同设计了 在血管生物学和再生领域吸引，训练和保留MD的生物医学研究 医学是其职业生涯中最关键的 - 居住培训。