Long-term Effects of a Natural Disaster on Cognitive Aging, Dementia, Health and Well-being of Older Adults

自然灾害对老年人认知老化、痴呆、健康和福祉的长期影响

基本信息

批准号：
10440502
负责人：
ELIZABETH A FRANKENBERG
金额：
$ 54.19万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-15 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10440502
关键词：
Address Affect Age Aging Alzheimer disease screening Alzheimer&apos s Disease Alzheimer&apos s disease related dementia Animal Model Anthropometry Area Attention Back Biological Blood Pressure Clinical Cognition Cognitive Cognitive aging Communities Complement Data Dementia Disasters Disease Earthquakes Economics Elderly Emotional Event Exposure to Family Friends Health Home Household and Family Human Impaired cognition Indian Ocean Individual Indonesia Inflammation Knowledge Light Link Literature Long-Term Effects Measurement Measures Mediating Natural Disasters Natural experiment Nature Neurosciences Observational Study Outcome Pathway interactions Personal Satisfaction Persons Physiological Play Population Poverty Premature Mortality Prevalence Process Public Domains Recovery Research Research Design Resource-limited setting Resources Respondent Risk Role Sampling Science Shock Site Source Stress Sum Sumatra Surveys Survivors Tablets Time Tsunami Water acetone hydrazone base blood-based biomarker cardiometabolic risk cardiometabolism cognitive performance cognitive testing data resource executive function experience follow-up innovation psychosocial reconstruction resilience response stressor

项目摘要

Abstract This project will provide rigorous scientific evidence on the effects, over the long-term, of exposure to stressors on cognitive performance, physical and psychosocial health and well- being of older adults in Indonesia using extremely rich population-representative longitudinal data collected from about 12,000 older respondents (>40y) before and for 20 years after the 2004 Indian Ocean earthquake and tsunami, the Study of the Tsunami Aftermath and Recovery (STAR). The tsunami was a large and unanticipated natural disaster that devastated some coastal communities while other comparable, nearby communities were untouched because of the wave direction, land and seabed topography. Exposure to the tsunami is, therefore, plausibly exogenous in our study area, coastal Aceh and North Sumatra, so that estimated effects of exposure to the stress of the tsunami can be given a causal interpretation. We will investigate how these effects vary with the nature of individual-specific experiences of the tsunami including being caught up in the water, losing family and loss of economic livelihoods. The research will document the extent of resilience and recovery among older adults in the face of the tsunami and its aftermath, as well as the role played in these processes by individual, household, family and community resources, including post-tsunami reconstruction. Special attention is paid to the measurement and interpretation of cognition and health. All older respondents will complete assessments used to screen for Alzheimer's disease which will be clinically validated. For a randomly selected sub-sample of older respondents, the screeners will be complemented with innovative neuroscience-based measures of executive functioning and emotional control assessed on tablets in the home. Validated cardio-metabolic biological risks will be collected for the same subsample of older adults to provide uniquely rich, high quality measures of key outcomes designed for this research. The links between cognition and health will be described using contemporaneous measures and exploiting longitudinal data on health that reach back 15 years.