Pathology Core

病理学核心

• 批准号: 10434860
• 负责人: Yuri Fedoriw
• 金额: $ 7.49万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-13 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10434860
• 关键词: AIDS related cancer; Address; Africa South of the Sahara; Area; Clinical Research; Collaborations; Country; Cytology Histology; Data; Development; Diagnosis; Diagnostic; Diagnostic Services; Disease; Ensure; Faculty; Foundations; Future; Geographic Locations; Goals; HIV; Histology; Hospitals; Human; Income; Infrastructure; Institution; Journals; Kaposi Sarcoma; Knowledge; Laboratories; Logistics; Lymphoma; Malawi; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Mentors; Multicenter Studies; Pathologist; Pathology; Patient Selection; Patient-Focused Outcomes; Phase; Procedures; Process; Prognosis; Research; Research Personnel; Research Project Grants; Resource Sharing; Resources; Services; Site; South Africa; Standardization; System; Telepathology; Time; Tissues; Training; Training and Education; Translational Research; United States; United States National Institutes of Health; Universities; Work; anticancer research; base; cancer care; cancer diagnosis; clinical care; cost effective; diagnostic tool; histological specimens; improved; innovation; low and middle-income countries; meetings; multidisciplinary; next generation; personalized medicine; prognostication; recruit; screening; skills; symposium; targeted treatment; working group

ABSTRACT: PATHOLOGY CORE Tissue diagnosis is essential for cancer care and research, and addressing HIV-related malignancies in Malawi and South Africa will be critically dependent on ensuring reliable access to robust pathology services. Achieving this requires strategic and multidisciplinary coordination of human and material resources for diagnostic pathology over time, as well as across geographic sites and scientific projects. This is a difficult undertaking even in high-income countries, and logistical challenges are significantly amplified in low- and middle-income countries. Initiatives to improve cancer care and research in SSA require accurate, cost- effective, and data-driven approaches to tissue acquisition and diagnosis, and strong regional pathology networks are an essential foundation to ultimately improve patient outcomes and conduct impactful research. Recognizing this, the UNC-Malawi-South Africa Cancer Consortium (UMSACC) will establish a shared- resource Pathology Core. The core will comprise of investigators from UNC Chapel Hill, UNC Project-Malawi and Kamuzu Central Hospital in Malawi, the University of the Witwatersrand, South Africa and Stellenbosch University, South Africa. The Pathology core will provide advanced and comprehensive diagnostic support to the multi-institutional research projects in this proposal through development of a central pathology review process, establish working groups within specific disease areas to actively identify regional best practices, and train the next generation of pathologists.

摘要：病理核心 组织诊断对于癌症护理和研究至关重要，解决了马拉维与HIV相关的恶性肿瘤 南非将严格依赖确保可靠获得强大病理服务的机会。 实现这一目标需要人类和物质资源的战略和多学科协调 随着时间的流逝以及整个地理站点和科学项目的诊断病理学。这是一个困难 即使在高收入国家中进行，后勤挑战在低和 中等收入国家。改善SSA癌症护理和研究的举措需要准确，成本 - 有效的，以及数据驱动的组织获取和诊断以及强大的区域病理 网络是最终改善患者结果并进行影响力研究的基础。 认识到这一点，UNC-Malawi - 南非洲癌症联盟（UMSACC）将建立共享 - 资源病理核心。核心将由UNC教堂山的调查员组成，UNC Project Malawi 马拉维的Kamuzu中央医院，Witwatersrand，南非和Stellenbosch 南非大学。病理核心将为 通过开发中央病理评论，该提案中的多机构研究项目 处理，在特定疾病领域建立工作组，以积极识别区域最佳实践，并 培训下一代病理学家。