Biodiversification of nutrients to meet dietary needs of the UK population: prevention and control of Type 2 diabetes and promotion of a healthy gut

营养生物多样化以满足英国人口的饮食需求：预防和控制 2 型糖尿病并促进健康的肠道

• 批准号: 10072588
• 金额: $ 36.1万
• 依托单位: PERUBIEN LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10072588
• 关键词: Biodiversification; nutrients; meet; dietary; needs

The quality of the UK's diet is a key public health issue. In 2017, 63% of the UK adult population was overweight, and 27% obese. Poor diet and being overweight or obese can lead to an increased risk of developing non-communicable diseases such as diabetes and cardiovascular disease. Obesity-related diseases cost the NHS more than £6bn/year in 2018 and will cost an estimated £9.7bn annually by 2050\. The impact of preventable ill health on the population threatens the long-term sustainability of the NHS, and a poor diet is a key component of this (British Medical Association, 2018).One of the main reasons the UK is facing challenges in promoting healthy eating habits and ensuring access to nutritious food for all is the limited availability of diverse nutritious foods and food ingredients, particularly in low-income areas (Food Standards Agency, 2019).We propose to undertake this collaborative research project to develop novel functional food ingredients using indigenous Peruvian crops, such as purple corn and yacon crops that are ancestrally recognised for their positive impact on health, to meet and diversify dietary needs of the UK population. Our special focus will be on prevention and self-control of type 2 diabetes (T2D) and promotion of a healthy gut.Facing an increasingly unhealthy population, there is a growing awareness of the link between diet and T2D. Without intervention, 5.5 million people could be living with T2D in the UK alone by 2030\. Along the same line, gut health is gaining popularity among consumers who pursue a holistic approach to prebiotics and probiotics, which are key to supporting a healthy gut microbiome, which plays an important role in overall health and well-being.Our project involves a comprehensive characterisation of nutrient and chemical content of purple corn and yacon-rich food ingredients, analysis of their potential systemic and gut health benefits _in vitro_, a detailed UK consumer research analysis, and the assessment of the food ingredients' nutrients and bioactives digestion and metabolism _in vitro._By incorporating resources that cannot be readily produced domestically due to regulatory restrictions, and land and climate limitations, we will diversify the UK's food supply and improve food security, something crucial with climate change and inflation causing food shortages. Our ultimate goal is to improve the life quality of vulnerable people in the UK, such as people at risk or living with T2D and reduce the burden on the UK's healthcare system.

英国饮食的质量是一个关键的公共卫生问题。 2017年，英国63％的成年人口超重，肥胖27％。饮食不良，超重或肥胖会导致患非通信疾病（例如糖尿病和心血管疾病）的风险增加。与肥胖有关的疾病的成本超过2018年的NHS超过60亿英镑，到2050年估计每年的费用为97亿英镑。可预防健康对人口的影响威胁了NHS的长期可持续性，而饮食差则是该NHS的长期可持续性（英国医学协会，2018年）。英国面临挑战方面面临健康饮食习惯面临的挑战之一，并确保所有人获得营养食品的机会是有限的，尤其是在较低的地区，尤其是在较低的食品中，尤其是在较低的食品中，尤其是在较低的餐饮中，尤其是在较低的国家 /地区。合作研究项目，旨在使用秘鲁土著农作物（例如紫色玉米和Yacon作物）开发新型功能性食品，这些作物因其对健康的积极影响而在祖先认可，以满足和多样化英国人口的饮食需求。我们的特别重点是预防和自我控制2型糖尿病（T2D）和促进健康的肠道。促进越来越不健康的人群，人们对饮食与T2D之间的联系越来越认识。没有干预，到2030年，仅英国就有550万人可以与T2D一起生活。沿着同一条线，肠道健康在购买益生元和益生菌的整体方法的消费者中越来越流行，这对于支持健康的肠道微生物组是关键，这在整体健康和福祉中起着重要作用。我们的项目涉及对紫色玉米和富含Yacon富含食物成分的养分和化学含量的全面表征，分析其潜在的系统性和肠道健康益处_在Vitro_中，一项详细的英国消费者研究分析，以及食品成分的评估以及对养分的评估，以及对生物活性的生物作用，以及对范围的构建，从而构成了digontion dotigation。气候限制，我们将使英国的粮食供应多样化并改善粮食安全，这是气候变化和通货膨胀导致粮食短缺的至关重要的。我们的最终目标是提高英国弱势群体的生活质量，例如处于危险的人或T2D生活，并减少英国医疗保健系统上的伯宁。