Aligning the Alliance of Genome Resources with FAIR and TRUST principles

使基因组资源联盟符合公平和信任原则

• 批准号: 10407901
• 负责人: CAROL J BULT
• 金额: $ 19.39万
• 依托单位: CALIFORNIA INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-18 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10407901
• 关键词: Address; Administrative Supplement; Animal Model; Area; Biomedical Research; Certification; Communities; Computer software; Data; Data Science; Development; Ecosystem; Educational workshop; Ensure; FAIR principles; Foundations; Funding; Genes; Goals; Human Biology; Infrastructure; Knowledge; Licensing; Maintenance; Mission; Modernization; Ontology; Organism; Outcome; Resources; TRUST principles; Trust; United States National Institutes of Health; Update; Work; data ecosystem; data format; data harmonization; data management; data repository; data resource; data submission; genome resource; genomic data; human disease; improved; interest; meetings; model organisms databases; response; seal; trend; web site

PROJECT SUMMARY The Alliance of Genome Resources (the Alliance) is a “knowledge commons” for expertly curated genomic data and annotations by model organism databases (MODs) and the Gene Ontology Consortium (GOC). Our mission is to facilitate the use of model organisms to understand human biology and disease. The Alliance is organized as two interconnected functional units: Alliance Central and Alliance Knowledge Centers. Alliance Central is responsible for development and maintenance of the software platform and shared modular infrastructure and for the coordination of data harmonization activities across the Knowledge Centers. Alliance Knowledge Centers such as the MODs and the GOC are responsible for expert curation and for submission of data to Alliance Central using common data formats. Knowledge Centers also are responsible for organism- specific user support activities, resources, and user access to data not yet supported by Alliance Central. The data management principles of the Alliance align well with the principles represented by FAIR principles (Findability, Accessibility, Interoperability, Reusability) and operational approaches reflected in the TRUST principles (Transparency, Responsibility, User focus, Sustainability and Technology). The focus for the administrative supplement in response to NOT-OD-21-089, includes the following aims: (1) address areas of improvement documented for the Alliance of Genome Resources (Alliance) in a FAIRShake assessment conducted under the auspices of the NIH Common Fund Data Ecosystem Project, (2) complete the Alliance's application to obtain Core Trust Seal certification, and (3) update information about the data and annotation licensing terms at the Alliance hosted on the (Re)usable Data Project (RDP). We will also participate in the workshops and meetings described in NOT-OD-21-089 which will allow the Alliance to compare the metrics/indicators we use to evaluate the impact of our resource to those of other relevant data resources and to adapt our metrics as needed to conform to new community standards or trends. The outcomes of the proposed work align well with the intent of NOT-OD-21-089 to increase the compliance of community data resources with FAIR and TRUST principles that are foundational to a modern data science ecosystem for the biomedical research community.

项目摘要 基因组资源联盟（联盟）是专业策划基因组的“知识共享” 模型生物数据库（MOD）和基因本体联盟（GOC）的数据和注释。我们的 使命是促进使用模型生物来了解人类生物学和疾病。联盟是 组织为两个互连功能单元：联盟中央和联盟知识中心。联盟 中央负责软件平台的开发和维护并共享模块化 基础架构以及整个知识中心的数据协调活动的协调。联盟 知识中心（例如mod和GOC）负责实验策划和提交 使用通用数据格式向联盟中心的数据数据。知识中心也负责生物 - 特定的用户支持活动，资源和用户访问Alliance Central尚未支持的数据。 联盟的数据管理原则与公平原则所代表的原则良好 （可发现性，可访问性，互操作性，可重复使用性）和信托中反映的操作方法 原则（透明度，责任，用户重点，可持续性和技术）。重点 对NOT-OD-21-089的响应行政补充，包括以下目的：（1）地址 在Fairshake评估中记录了基因组资源（联盟）联盟的改进 在NIH共同基金数据生态系统项目的主持下进行的（2）完成联盟的 获得核心信托密封认证的申请，（3）更新有关数据和注释的信息 在（RE）可用数据项目（RDP）上托管的联盟中的许可条款。我们还将参加 NOT-OD-21-089中描述的研讨会和会议将使联盟能够比较 我们使用的指标/指标来评估资源对其他相关数据资源的影响以及 根据需要调整我们的指标，以符合新的社区标准或趋势。结果 拟议的工作与NOT-OD-21-089的意图非常吻合，以提高社区数据的遵守 具有公平和信任原则的资源是现代数据科学生态系统的基础 生物医学研究界。