DuoVIAL LACR Modification - Visual Inspection, Process Optimisation & Quality Assurance

DuoVIAL LACR 修改 - 目视检查、工艺优化

• 批准号: 10062481
• 金额: $ 1.7万
• 依托单位: PACIFI LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=10062481
• 关键词: DuoVIAL; LACR; Modification; Visual; Inspection

DuoVIAL is a unique, patented, pharmaceutical primary packaging system, enabling safer, easier and more efficient reconstitution of lyophilised biological formulations, including vaccines and diagnostic reagents. Designed to Protect, Mix & Deliver, respectively the product, healthcare professionals, patients and the planet, the system is more cost effective, more compact and efficient in its' materials utilisation, whilst consisting of recyclable glass and aluminium materials. Advanced laser technologies have now evolved sufficiently to make this solution technically viable, as well as exceptionally scalable to enable commercial advantages. The ultimate application, achieving the greatest impact within global healthcare, is for lyophilised vaccines, shipped via the cold chain to developing markets.The product advantages can equally be applied to other high-value sectors, including Diagnostics, Probiotics, Wound Care and Medical Devices. Application of these laser technologies has typically been optimised for flat screen electronic displays, e.g. mobile phones, silicon wafers. Significantly more challenging is the application and optimisation of the Lasered Annular Cleave Ring (LACR) process applicable to DuoVIAL's inherently complex 3D form, having relatively significant variability and tolerances. The primary objective is to ensure the consistent 'clean-cleave' activation of a single aesthetic disc within the reconstituted formulation.Underpinning the quality assurance of current product and enabling DuoVIAL applications to expand into more challenging and regulated healthcare markets requires the development of New Metrology & Vision Inspection Systems, which can quantifiably measure, semi-transparent, µm LACR features, inline, on 100% of components and feedback into the high speed LACR process, resulting in optimised laser processing parameters.The cost of quality, or rather the lack thereof is, wasted raw materials, reduced production efficiencies, lower quality products and market opportunities unable to be exploited. Investing in R&D to underpin quality assurance and optimised processes is critical to ensuring competitive advantage in a global market, as well as being able to continue to innovate and introduce new products to market and challenge the status quo.

DuoVIAL 是一种独特的专利药品初级包装系统，能够更安​​全、更轻松、更高效地重构冻干生物制剂，包括疫苗和诊断试剂，旨在分别保护、混合和交付产品、医疗保健专业人员、患者和地球。该系统在材料利用方面更具成本效益、更紧凑和高效，同时由可回收玻璃和铝材料组成，先进的激光技术现已充分发展，使该解决方案在技术上可行，并且具有可行性。具有卓越的可扩展性，可实现商业优势，在全球医疗保健领域产生最大影响的最终应用是通过冷链运输到发展中市场的冻干疫苗。产品优势同样可以应用于其他高价值领域，包括诊断、益生菌、伤口护理和医疗设备。这些激光技术的应用通常针对平板电子显示器进行优化，例如激光技术的应用和优化。环形切割环 (LACR) 工艺适用于 DuoVIAL 固有的复杂 3D 形式，具有相对显着的可变性和公差，主要目标是确保重构配方中单个美观圆盘的一致“干净切割”激活。支撑质量保证。当前产品的发展并使 DuoVIAL 应用扩展到更具挑战性和监管的医疗保健市场，需要开发新的计量和视觉检测系统，该系统可以量化测量、半透明、μm LACR 具有 100% 在线组件并反馈到高速 LACR 工艺中，从而优化激光加工参数。质量成本，或者更确切地说缺乏质量成本，是浪费原材料、降低生产效率、降低产品质量和投资研发以支持质量保证和优化流程对于确保在全球市场中的竞争优势以及能够继续创新并向市场推出新产品并挑战市场至关重要。现状。