NorthStar Node of the Clinical Trials Network: Facebook intervention for preventing opioid relapse among American Indian Women

临床试验网络 NorthStar 节点：Facebook 干预美国印第安妇女预防阿片类药物复发

• 批准号: 10391905
• 负责人: GAVIN BART
• 金额: $ 23.87万
• 依托单位: HENNEPIN HEALTHCARE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-15 至 2022-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10391905
• 关键词: Abstinence; Address; Adopted; Adoption; Adult; Advisory Committees; Affect; Alaska Native; American Indians; Biological; COVID-19 pandemic; Clinical Trials Network; Communities; Development; Effectiveness of Interventions; Facebook; Funding; Future; Gender; Generations; HIV; Hepatitis C; Individual; Intervention; Intervention Trial; Interview; Lead; Minnesota; Modeling; Morbidity - disease rate; Opioid; Overdose; Participant; Pharmacotherapy; Phase; Population; Public Health; Randomized; Recovery; Relapse; Research; Resources; Sampling; Social Network; Social support; Stress; Technology; Telephone; Testing; Time; Trauma; Woman; Work; addiction; base; care providers; control trial; coping; cultural values; design; digital; disorder later incidence prevention; evidence base; healthcare community; innovation; medication-assisted treatment; men; mortality; opioid use; opioid use disorder; perceived stress; prescription opioid; prevent; preventive intervention; prototype; recruit; resilience; social; social media; stress management; stress reactivity; substance use; virtual

PROJECT SUMMARY In 2017, American Indian and Alaska Native (AIAN) adults in Minnesota (MN) were six times more likely to die of an overdose involving opioids than whites, representing the greatest disparity observed between AIAN and whites in the US. Medication for opioid use disorder (MOUD) is an evidence-based approach, and strategies to promote continuation of pharmacotherapy and support OUD recovery are important. Gender- specific factors affecting opioid use relapse and recovery that are more prevalent in women compared with men include perceived stress, trauma, and social support for abstinence. AIAN gender-specific interventions for OUD do not exist. Research has documented the positive impact of social networks and social support on abstinence from substance use. However, understanding how best to leverage social support remains a key challenge for the addiction’s treatment field. We propose to address these gaps by developing a social digital (Facebook) intervention to promote stress management and social network support for opioid abstinence among AIAN women. Virtual digital platforms have potential for greater reach and scale. Consistent with the AIAN cultural value of interdependence, social media-formed groups to prevent opioid relapse could lead to greater adoption and sustainability by encouraging collaborative efforts across generations of AIAN women and leveraging community resilience for coping with stress. The overall objective of this one-year, Phase I, pilot preparatory study is to develop and beta-test a Facebook intervention for reducing opioid relapse among AIAN women. This project was designed with community partners at the MN Indian Women’s Resource Center (MIWRC). A study-specific community advisory committee will guide all project activities. The Specific Aim is to develop and beta-test the Facebook intervention content and prototype. In this formative work, we will conduct individual qualitative interviews by phone/video with a purposefully recruited sample of AIAN women with OUD, with at least one month of abstinence and receiving MOUD (n=12); as well as addiction care providers and AIAN community stakeholders (n=12). Participants will provide input on the cultural relevance and perceived effectiveness of intervention content. A Facebook intervention prototype will be developed, beta-tested, and iteratively refined with AIAN women (n=10). Results will inform development of a future pilot randomized control trial of the intervention. This project is innovative for developing a gender-specific, socially based, opioid relapse prevention intervention using social media technologies that are culturally relevant and already adopted. This proof-of-concept study is the first step to an intervention that could ultimately be widely disseminated through addiction health care and community-based settings as well as social media; and serve as a model for developing social digital addictions treatment in other populations, enhancing overall reach and impact.

项目摘要 2017年，明尼苏达州（明尼苏达州）的美洲印第安人和阿拉斯加本地人（Aian）成年人的可能性是 与白人相比，涉及阿片类药物过量的死亡，代表Aian之间观察到的最大差异 和白人在美国。绿核酸使用障碍药物（MOUD）是一种基于证据的方法，并且 促进药物疗法和支持恢复的策略很重要。性别- 影响阿片类药物使用缓解和恢复的特定因素在女性中更为普遍 男人包括感知到的压力，创伤和对禁欲的社会支持。艾安性别特定的干预措施 因为不存在。研究记录了社交网络和社会支持对 禁欲使用物质。但是，了解如何最好地利用社会支持仍然是关键 成瘾治疗领域的挑战。我们建议通过建立社交数字来解决这些差距 （Facebook）干预措施促进压力管理和社交网络支持，以避免阿片类药物 在艾安妇女中。虚拟数字平台具有更大的覆盖范围和规模的潜力。与 相互依存的Aian文化价值，社交媒体形成的群体以防止阿片类药物继电器可能导致 通过鼓励几代艾安妇女的合作努力，更大的收养和可持续性 并利用社区弹性应对压力。这一一年的第一阶段飞行员的总体目标 准备研究是开发和β测试的Facebook干预措施，以减少Aian的阿片类药物接力 女性。该项目是由MN印度妇女资源中心的社区合作伙伴设计的 （MIWRC）。一个针对特定研究的社区咨询委员会将指导所有项目活动。具体目的是 开发和β测试Facebook干预内容和原型。在这项形成性的工作中，我们将进行 通过电话/视频进行个人定性访谈，并有目的地招募的Aian妇女的样本， 至少有一个月的禁欲和接收穆德（n = 12）；以及成瘾护理提供者和 艾安社区利益相关者（n = 12）。参与者将提供有关文化相关性和感知的意见 干预内容的有效性。 Facebook干预原型将开发，经过β测试，并 迭代地与艾安妇女（n = 10）进行完善。 结果将为未来的飞行员随机控制试验提供干预措施的开发。这个项目是 创新用于开发特定性别，基于社会的，阿片类药物的预防干预措施 具有文化相关并且已经采用的媒体技术。这项概念验证研究是第一次 一步迈出干预措施，该干预措施最终可以通过成瘾医疗保健和 基于社区的环境和社交媒体；并充当发展社会数字的典范 其他人群中的成瘾治疗，增强了整体影响力和影响。