Medical University of South Carolina - Cancer Center Support Grant

南卡罗来纳医科大学 - 癌症中心支持补助金

基本信息

批准号：
10377462
负责人：
RAYMOND N. DUBOIS
金额：
$ 215.63万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-04-01 至 2024-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10377462
关键词：
Academic Medical Centers Achievement Address African American population Automobile Driving Awareness Basic Science Biometry Cancer Biology Cancer Burden Cancer Center Cancer Center Support Grant Cancer Control Cancer Death Rates Cancer Research Project Cause of Death Cell Separation Cells Cervical Cessation of life Charge Clinic Clinical Clinical Research Clinical Sciences Clinical Trials Colorectal Communities Development Diagnosis Diagnostic Disease Doctor of Philosophy Education Ensure Exercise Extramural Activities Flow Cytometry Fostering Funding Genetic Geographic state Geography Goals Head and neck structure Healthcare Intervention Studies Journals Kidney Leadership Lung Malignant Neoplasms Medical Mission Morbidity - disease rate Movement National Cancer Institute Nature Oncology Outcome Outreach Research Participant Patient Care Patients Peer Review Persons Physicians Policies Population Heterogeneity Population Research Population Sciences Prevention Prevention approach Preventive Prostate Public Policy Publications Research Research Infrastructure Research Personnel Resources Rural Rural Community Science Scientific Advances and Accomplishments Scientist Services Shapes South Carolina Strategic Planning Technology Therapeutic Therapeutic Clinical Trial Thinking Tissues Tobacco use Training Translating Translational Research Translations Unhealthy Diet Universities Ursidae Family Work anticancer research base bench to bedside biobank cancer care cancer education cancer health disparity cancer prevention cancer therapy career career development cellular imaging community based research community engagement ethnic minority high school improved innovation interdisciplinary collaboration lifestyle factors lipidomics malignant breast neoplasm medically underserved molecular imaging mortality multidisciplinary next generation novel strategies operation outreach prevent programs racial disparity racial minority ranpirnase recruit socioeconomics translational pipeline tumor immunology underserved community

项目摘要

OVERALL: SUMMARY The Hollings Cancer Center (HCC) at the Medical University of South Carolina (MUSC) seeks renewal of its National Cancer Institute (NCI) designation via the P30 Cancer Center Support Grant (CCSG) mechanism. As South Carolina's (SC) leading academic medical center, MUSC is charged with building basic, translational, clinical, and population-based research programs that address the state's significant healthcare needs. The mission of the HCC is to reduce the cancer burden in SC through transformative research, patient care, prevention, and public policy. To accomplish this mission, HCC leadership built a robust, multidisciplinary center that includes 107 cancer scientists. Innovative, high-impact research is driven by HCC’s four research programs: Cancer Biology, Cancer Immunology, Developmental Cancer Therapeutics, and Cancer Control. The rapid pace of discovery and movement toward effective translational research is supported by five shared research resources: Lipidomics, Flow Cytometry & Cell Sorting, Cell & Molecular Imaging, Biorepository & Tissue Analysis, and Biostatistics. During the current project period, the HCC successfully leveraged CCSG funding and its NCI-designated cancer center status to harness, expand and improve the center’s research capabilities to decrease the state’s cancer burden. HCC supported recruitment of 26 new cancer scientists. The annual direct peer-reviewed extramural research funding (excluding training and career development awards) increased to $21.6M, with $10.5M from NCI. HCC boasts the state’s largest clinical trials operation that provides centralized support for conducting the most contemporary cancer trials. During the past year, the HCC recruited 1,266 patients to interventional studies and 254 patients to non-interventional studies. HCC made significant progress in overcoming the challenges inherent in recruiting racial and ethnic minorities to participate in research. In 2017, 33% of research participants were racial or ethnic minorities, with more than half residing in rural communities federally designated as medically underserved. This progress has been maintained for over two decades by progressive, HCC-led outreach, community engagement, and cancer education services. With the charge of training the next generation of diverse and exceptional cancer physicians and scientists, the center developed the state’s only comprehensive cancer education pipeline for learners across the entire education continuum, from high school through early professional career development. The HCC is committed to providing access to the latest research, educational, and clinical advances to all of South Carolina, and has never been better equipped to fulfill its mission. Led by a new center director appointed in 2017, the HCC will implement its 2023 strategic plan to advance scientific discovery, make impactful contributions to the understanding of cancer biology in a diverse population, and translate discoveries into transformative approaches to cancer control, diagnosis, treatment, and public policy.

总体：总结南卡罗来纳医科大学 (MUSC) 霍林斯癌症中心 (HCC) 寻求更新其通过 P30 癌症中心支持补助金 (CCSG) 机制获得美国国家癌症研究所 (NCI) 指定为 As。南卡罗来纳州 (SC) 领先的学术医疗中心，MUSC 负责建设基础、转化、满足该州重大医疗保健需求的临床和基于人群的研究项目。 HCC 的使命是通过变革性研究、患者护理、为了完成这一使命，HCC 领导层建立了一个强大的、多学科的团队。该中心由 107 名癌症科学家组成，其创新性、高影响力的研究由 HCC 的四项研究推动。课程：癌症生物学、癌症免疫学、发育性癌症治疗和癌症控制。发现和迈向有效转化研究的快速步伐得到了五个共享的支持研究资源：脂质组学、流式细胞术和细胞分选、细胞和分子成像、生物样本库和在当前项目期间，HCC 成功利用了 CCSG。资金及其 NCI 指定癌症中心地位，以利用、扩展和改进该中心的研究 HCC 支持招募 26 名新的癌症科学家。年度直接同行评审的校外研究经费（不包括培训和职业发展奖）增加至 2160 万美元，其中 NCI 提供 1050 万美元，拥有该州最大的临床试验业务。在过去的一年里，为进行最新的癌症试验提供了集中支持。 HCC 招募了 1,266 名患者进行介入性研究，并招募了 254 名患者进行非介入性研究。在克服招募种族和族裔少数群体的固有挑战方面取得了重大进展 2017 年，33% 的研究参与者是少数族裔或族裔，超过一半居住在联邦指定的医疗服务不足的农村社区。通过由 HCC 主导的进步、社区参与和癌症领域的进步，维持了二十多年负责培训下一代多样化和特殊的癌症。医生和科学家，该中心开发了该州唯一的综合癌症教育渠道整个教育过程中的学习者，从高中到早期职业生涯 HCC 致力于提供最新的研究、教育和临床知识。向整个南卡罗来纳州推进，并且在新的领导下完成其使命。 2017 年任命中心主任后，HCC 将实施其 2023 年战略计划，以推进科学发展发现，为了解不同人群的癌症生物学做出有影响力的贡献，以及将发现转化为癌症控制、诊断、治疗和公共政策的变革性方法。