Ethno-epidemiology of HCV, HIV and Overdose associated with Drug Markets and Drug Tourism

与毒品市场和毒品旅游相关的丙型肝炎病毒、艾滋病毒和药物过量的民族流行病学

基本信息

批准号：
10330754
负责人：
STEFFANIE A. STRATHDEE
金额：
$ 11.61万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-04-01 至 2025-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10330754
关键词：
AIDS prevention Alabama Attenuated Buprenorphine California Clinical Clinical Psychology Communicable Diseases Communities Competence Country Data Analyses Developing Countries Development Epidemiologist Epidemiology Fellowship Foundations Future Goals HIV Hepatitis C virus Injecting drug user International Intervention Latinx Mediator of activation protein Medical Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Methadone Mexico Motivation Overdose Pharmaceutical Preparations Population Postdoctoral Fellow Prevention Research Psychologist Research Research Personnel Suboxone Substance Use Disorder Training Universities barrier to care design drug market ethnic minority population experience methadone treatment opioid use disorder parent grant post-doctoral training pre-doctoral prescription opioid preventive intervention programs racial and ethnic residence secondary analysis social stigma treatment comparison treatment effect treatment research

项目摘要

Abstract of Diversity Supplement The proposed Diversity Supplement is designed to promote diversity in the scientific community through the training of Samantha Schiavon, M.A., a Latinx clinical psychologist with experience conducting substance use disorder treatment research among vulnerable and racial/ethnic minority populations. Ms. Schiavon has obtained a strong research background through her pre-doctoral training in the Medical/Clinical Psychology Doctoral Program at the University of Alabama at Birmingham and will continue to advance her research competencies as a research postdoctoral fellow at the University of California San Diego (UCSD). Through this supplement, Ms. Schiavon will build her research capacities through examining the impact of stigma on motivations to initiate medication for opioid use disorder (MOUD) treatment among persons who inject drugs (PWID) within Mexico and the U.S. She will train under the mentorship of Dr. Steffanie Strathdee (primary mentor and PI on parent grant), a world-renowned infectious disease epidemiologist focused on HIV prevention research in developing countries, Dr. Thomas Patterson (co-mentor), known for his HIV/AIDS prevention interventions along the Mexico-U.S. border region, and Dr. Laramie Smith (co-mentor), an expert in stigma research among PWID. Through secondary data analysis, this supplement will expand upon the aims of the parent grant to identify cross-cultural differences between Mexico and the U.S. in MOUD and substance use disorder stigma as potential barriers to MOUD treatment initiation intentions among PWID. The specific aims are to: 1) to examine country of primary residence (Mexico v. US) as a moderator between anticipated substance use disorder stigma and intentions to initiate MOUD treatment; 2) to assess differences in anticipated MOUD treatment (i.e., buprenorphine/suboxone vs. methadone) stigma by country of primary residence (Mexico v. US); and 3) to examine anticipated MOUD stigma as a mediator between country of primary residence (Mexico v. US) and MOUD treatment initiation intentions. These results will inform the development of culturally responsive interventions to reduce stigma as a barrier to MOUD treatment initiation and will serve as the foundation for Ms. Schiavon’s future K23 proposal. Therefore, this supplement will not only provide crucial support to enhance Ms. Schiavon’s training throughout her postdoctoral fellowship at UCSD, but will also facilitate her transition to becoming an independent clinical researcher through a K23 award focused on reducing barriers to MOUD treatment initiation among international populations of PWID.

多样性补充摘要拟议的多样性补充旨在通过 Latinx临床心理学家萨曼莎·史扬（Samantha Schiavon）的培训，具有进行药物使用的经验弱势和种族/族裔少数民族人口的疾病治疗研究。 Schiavon女士有通过医学/临床心理学的博士前培训获得了强大的研究背景伯明翰阿拉巴马大学的博士课程，并将继续推进她的研究加利福尼亚大学圣地亚哥分校（UCSD）的研究博士后研究员的能力。通过这个补充，Schiavon女士将通过检查污名对在注射药物的人中启动阿片类药物使用障碍（MOUD）治疗药物的动机（PWID）在墨西哥和美国，她将在Steffanie Strathdee博士的心态下训练（主要）对父母格兰特的导师和PI），这是一位致力于艾滋病毒的世界知名传染病医生在发展中国家的预防研究，托马斯·帕特森（Thomas Patterson）博士（Co-Insor），以艾滋病毒/艾滋病而闻名墨西哥 - 美国的预防干预措施。边境地区和拉米·史密斯（Laramie Smith）博士（同事），专家 PWID之间的污名研究。通过二级数据分析，该补充将扩大父母的赠款，以确定墨西哥与美国在MOUD和基板上的跨文化差异使用障碍的污名作为PWID中MOUD治疗计划的潜在障碍。具体目的是：1）审查主要居住国（墨西哥诉US）作为预期的主持人药物使用障碍的污名和启动MOUD治疗的意图； 2）评估差异预期的MOUD治疗（即丁丙诺啡/亚oxone vs. Metagadone）的污名住宅（墨西哥诉US）； 3）将预期的穆德污名作为一个国家之间的调解人初级居住（墨西哥诉US）和MOUD治疗计划。这些结果将告知开发具有文化反应式干预措施，以减少污名作为MOUD治疗计划的障碍并将成为Schiavon女士未来K23提案的基础。因此，这种补充不会仅提供至关重要的支持，以增强Schiavon女士在整个博士后奖学金中的培训 UCSD，但也将促进她通过K23过渡到成为独立临床研究人员奖项的重点是减少国际PWID人口中MOUD治疗计划的障碍。