IARC Monographs on the Identification of Carcinogenic Hazards to Humans

IARC 关于人类致癌危害鉴定的专着

基本信息

批准号：
10319666
负责人：
MARY K. SCHUBAUER-BERIGAN
金额：
$ 98.03万
依托单位：
INTERNATIONAL AGENCY FOR RES ON CANCER
依托单位国家：
美国
项目类别：
财政年份：
1985
资助国家：
美国
起止时间：
1985-09-01 至 2026-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10319666
关键词：
Achievement Animals Attention Biological Products Cancer Control Carcinogens Characteristics Chemicals Classification Collaborations Complex Mixtures Conflict of Interest Consensus Country Data Ensure Environmental and Occupational Exposure Evaluation Exposure to Freedom Funding Geographic Locations Goals Government Grouping Guidelines Health Human Income International International Agency for Research on Cancer Life Literature Malignant Neoplasms Measures Methodology Methods Modernization Molecular Epidemiology Monograph National Toxicology Program Occupational Exposure Play Preventable cancer cause Procedures Process Public Health Publications Research Role Science Scientific Evaluation Social Network Source Stream Technology Time Toxicology U-Series Cooperative Agreements United States Environmental Protection Agency World Health Organization base carcinogenicity digital diversity and inclusion evidence base experience exposed human population hazard health assessment health organization improved interest lifestyle factors low and middle-income countries meetings news novel novel strategies prevent programs public health relevance screening searchable database systematic review tool trustworthiness web-based tool working group

项目摘要

Project Summary/Abstract Since 1971, the IARC Monographs on the Identification of Carcinogenic Hazards to Humans has provided an evidence-based approach to identifying the preventable causes of human cancer. Organizations worldwide rely on the IARC Monographs as a trustworthy source of carcinogenicity evaluations in their efforts to control cancer. Agents evaluated by the Monographs encompass chemicals, physical and biological agents, complex mixtures, occupational exposure circumstances, and other exposures of everyday life. To date, 1021 agents have been evaluated, with 121 classified as “carcinogenic”, 89 as “probably carcinogenic”, and 315 as “possibly carcinogenic” to humans. Agents are selected for evaluation based on evidence of human exposure and of carcinogenicity, and public health importance. Monographs are developed by independent global experts without conflicts of interest. Each Monograph includes systematic reviews of the pertinent scientific literature covering three unique streams of evidence (cancer in humans, cancer in experimental animals, and mechanistic evidence). The

项目概要/摘要自 1971 年以来，IARC 关于人类致癌危害鉴定的专着提供了一种基于证据的方法来确定人类健康问题的可预防原因世界各地的组织都将 IARC 专着视为值得信赖的来源。其控制癌症的药物的致癌性评估。专着涵盖化学品、物理和生物制剂、复杂混合物、职业暴露情况，以及日常生活中的其他暴露，迄今为止，1021 已对物质进行了评估，其中 121 种被归类为“致癌”，89 种被归类为“可能致癌” 致癌”，315 为“可能对人类致癌”。基于人类接触和致癌性以及公共卫生证据的评估专着由独立的全球专家编写，没有冲突。每本专着都包含对相关科学文献的系统评论。涵盖三个独特的证据流（人类癌症、实验癌症）动物和机械证据）。