INSPIRE: INtegrated Short-term PallIative REhabilitation to improve quality of life and equitable care access in incurable cancer

INSPIRE：综合短期姑息康复，以提高无法治愈癌症的生活质量和公平护理机会

基本信息

批准号：
10047799
负责人：
金额：
$ 212.94万
依托单位：
KING'S COLLEGE LONDON
依托单位国家：
英国
项目类别：
EU-Funded
财政年份：
2022
资助国家：
英国
起止时间：
2022 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=10047799
关键词：
INSPIRE INtegrated Short term PallIative

项目摘要

Disability related to incurable cancer affects over a million Europeans each year. Our objective is to test the clinical and cost effectiveness of an integrated short-term palliative rehabilitation intervention, to improve function and quality of life in people affected by incurable cancer. At the core of INSPIRE is a multinational randomised controlled trial across five European countries. We will recruit 340 participants to assess the clinical and cost-effectiveness of palliative rehabilitation on quality of life, disability, symptom burden and goal attainment in people with incurable cancer. If positive, the trial could result in a scalable and equitable intervention that improves function and quality of life in people with incurable cancer, and reduces the burden of care for their families. The intervention can be adapted and integrated into different health systems using existing staff and services, with little or no additional cost. To support our ambition to make palliative rehabilitation part of routine care for people with incurable cancer we also conduct: - comparative analysis of health services to understand current integration of rehabilitation across oncology and palliative care services; - mixed-method evaluations of equity and inclusivity, processes and implementation for the intervention, at patient, health service and health system levels; - evidence synthesis and a Delphi consensus on indicators, core interventions, outcomes, and integration methods, to develop a framework for palliative rehabilitation practice and policy. The INSPIRE consortium brings together leaders in palliative care, oncology and rehabilitation from Nordic, Southern and Northern European countries, with complementary expertise in health services research, trials of complex interventions, mixed method evaluations, statistics and economics. We are partnering with European civil society organisations to ensure citizen engagement and dissemination at the highest level.

与无法治愈的癌症有关的残疾每年影响超过一百万的欧洲人。我们的目标是测试综合的短期姑息治疗干预措施的临床和成本效益，以改善受无法治愈的癌症影响的人的功能和生活质量。 Inspire的核心是五个欧洲国家的跨国随机对照试验。我们将招募340名参与者来评估姑息治疗对生活质量，残疾，症状负担和无法治愈的癌症患者目标的临床和成本效益。如果肯定，该试验可能会导致可扩展且公平的干预措施，从而改善癌症患者的生活和生活质量，并减轻对家人的护理负担。可以使用现有的员工和服务将干预措施调整并集成到不同的卫生系统中，而几乎没有或没有额外的费用。为了支持我们为无法治愈的癌症患者进行姑息治疗的一部分的野心： - 对卫生服务的比较分析，以了解跨肿瘤学和姑息治疗服务的当前康复整合； - 对干预，患者，卫生服务和卫生系统水平的干预措施的公平和包容性，流程和实施的混合方法评估； - 关于指标，核心干预措施，结果和集成方法的证据合成和Delphi共识，以开发姑息治疗实践和政策的框架。 Inspire联盟将来自北欧，南欧和北欧国家的姑息治疗，肿瘤学和康复领域的领导者汇集在一起，并具有卫生服务研究中的互补专业知识，复杂干预措施的试验，混合方法评估，统计和经济学。我们正在与欧洲民间社会组织合作，以确保公民参与和传播最高水平。