Cardiovascular Disease Research Training Program in Haiti

海地心血管疾病研究培训项目

• 批准号: 10302601
• 负责人: Margaret Leighton McNairy
• 金额: $ 24.97万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10302601
• 关键词: Address; Adult; African American; Cardiovascular Diseases; Clinic; Clinical Research; Communicable Diseases; Country; Educational workshop; Environmental Pollutants; Epidemic; Evaluation; Faculty; Foundations; Goals; Grant; HIV; Haiti; Haitian; Health; Hypertension; Infection; International; Intervention; Knowledge; Medicine; Mentors; Morbidity - disease rate; Outcome; Persons; Poverty; Prevalence; Psychological Stress; Recording of previous events; Research; Research Personnel; Research Training; Risk Factors; Scientist; Training; Training Programs; United States National Institutes of Health; Universities; cardiovascular disorder risk; career development; food insecurity; high salt diet; improved; innovation; lead exposure; leadership development; mortality; next generation; programs; skills; social determinants; symposium; uptake

ABSTRACT Cardiovascular disease (CVD) is the most common non-communicable disease and the leading cause of morbidity and mortality in Haiti. It has surpassed infectious diseases over the past decade. Hypertension (HTN) is the single most common CVD risk factor in Haitian adults and its onset is 10-20 years earlier than among Black Americans in the US. Potential drivers of HTN in Haiti include social determinants such as extreme poverty, food insecurity, a high salt diet, psychological stress, and also environmental pollutants such as high lead exposure. Concurrently, Haiti continues to have the highest HIV prevalence in the region with over 35% of persons living with HIV having HTN. To curb this alarming CVD epidemic, Haiti urgently needs CVD research training for both young investigators and research staff in order to increase its capacity to conduct interdisciplinary, impactful CVD research. This proposal builds on a ~40-year history in Haiti of NIH research and Fogarty training by the Groupe d’Etude du Sarcome et des Infections Opportunistes (GHESKIO) and its US collaborating partner, Weill Cornell Medicine. The Cornell-GHESKIO partnership began with a focus on HIV and since 2015 has expanded to address the CVD epidemic in Haiti. We have built a strong foundation with 8 active NIH and foundation grants in CVD research and the creation of the GHESKIO NCD Clinical and Research Unit. We now need to train a skilled workforce of specialized CVD researchers who can expand Haiti’s research portfolio and transform research findings into practice. The goal of this training program is to strengthen research that will ultimately improve CVD-related health outcomes in Haiti and the world. Our three training objectives include: 1) to provide long-term mentored CVD research training to 8 Haitian clinician scientists through MPH coursework at Quisqueya University with mentored CVD research in Haiti; 2) to train 24 medium-term research staff in CVD knowledge and technical research skills through a new 1-year CVD Core Research Course taught by Haitian and international faculty; and 3) to establish a CVD Implementation Network of 6 CVD clinics to increase the uptake, optimization, and evaluation of high-impact CVD interventions in Haiti. Staff at the Network clinics will have opportunities for short-term training including participation in monthly CVD Grand Rounds and participation in 1-week workshops within the CVD Core Research Course. In addition, we will sponsor an annual national CVD Research Conference with a focus on trainee leadership and career development. The proposed program is the first CVD research training program in Haiti and brings innovation in CVD coursework, new research mentors and faculty, and a platform for building implementation capacity for CVD interventions across the country. We are committed to training the next generation of CVD researchers in Haiti.

抽象的 心血管疾病（CVD）是最常见的非传染性疾病，也是主要原因 过去十年，海地的发病率和死亡率已超过高血压。 (HTN) 是海地成年人中最常见的 CVD 危险因素，其发病时间比海地早 10-20 年。 在美国黑人中，海地高血压的潜在驱动因素包括以下社会决定因素： 极端贫困、粮食不安全、高盐饮食、心理压力以及环境污染物 同时，海地的艾滋病毒感染率仍然是该地区最高的，艾滋病毒感染率超过 10%。 35% 的艾滋病毒感染者患有高血压，为了遏制这一令人震惊的 CVD 流行，海地迫切需要 CVD。 对年轻研究者和研究人员进行研究培训，以提高其开展研究的能力 跨学科、有影响力的 CVD 研究。 该提案建立在海地 NIH 研究和 Groupe Fogarty 培训约 40 年的历史基础上 d’Etude du Sarcome et des Infections Opportunistes (GHESKIO) 及其美国合作伙伴威尔康奈尔大学 康奈尔大学与 GHESKIO 的合作伙伴关系始于艾滋病毒领域，自 2015 年以来已扩展到医学领域。 我们通过 8 项活跃的 NIH 和基金会拨款奠定了坚实的基础，以应对海地的 CVD 疫情。 我们现在需要培训一名 CVD 研究人员并创建 GHESKIO NCD 临床和研究部门。 由专门的 CVD 研究人员组成的熟练劳动力队伍可以扩大海地的研究组合并实现转型 研究成果付诸实践。 该培训计划的目标是加强研究，最终改善与 CVD 相关的疾病 我们的三个培训目标包括：1) 提供长期指导。 通过 Quisqueya 大学的 MPH 课程，为 8 名海地临床科学家提供 CVD 研究培训 指导海地的 CVD 研究；2) 培训 24 名中期研究人员的 CVD 知识和技术 通过由海地和国际教师教授的新的为期一年的 CVD 核心研究课程来提高研究技能； 3) 建立一个由 6 个 CVD 诊所组成的 CVD 实施网络，以增加采用、优化和实施 对海地高影响力的 CVD 干预措施进行评估 网络诊所的工作人员将有机会 短期培训，包括参加每月 CVD 大查房和参加为期 1 周的培训 CVD 核心研究课程中的研讨会 此外，我们还将赞助一年一度的全国 CVD 活动。 研究会议的重点是学员领导力和职业发展。 海地首个 CVD 研究培训项目，带来 CVD 课程和新研究的创新 导师和教职人员，以及一个用于建设整个 CVD 干预实施能力的平台 我们致力于在海地培训下一代 CVD 研究人员。