Health-professional Education Partnership Initiative - Transforming Ugandan Institutions Training Against HIV/AIDS (HEPI-TUITAH)

卫生专业教育伙伴关系倡议 - 乌干达艾滋病毒/艾滋病培训机构转型 (HEPI-TUITAH)

• 批准号: 10286022
• 负责人: Celestino Obua
• 金额: $ 25.89万
• 依托单位: MBARARA UNIVERSITY/SCIENCE/ TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-19 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10286022
• 关键词: AIDS/HIV problem; Access to Information; Affect; Africa; Alzheimer' s Disease; Alzheimer' s disease model; Alzheimer' s disease related dementia; Alzheimer' s disease risk; Automobile Driving; Behavior assessment; Biological Markers; Caregiver support; Caring; Central Nervous System Infections; Chronic; Clinical; Clinical Research; Communities; Consensus; Data; Dementia; Development; Diagnosis; Diagnostic; Early Diagnosis; Education; Elderly; Epidemiology; Evaluation; Exposure to; Family; Guidelines; Health; Health Occupations; Health Personnel; Health care facility; Household; Hybrids; Individual; Institution; Intervention Studies; Investments; Knowledge; Life; Medical; Mentors; Modeling; Outcome; Patients; Persons; Poverty; Pregnancy Complications; Prevalence; Primary Health Care; Professional Education; Quality of life; Research; Research Methodology; Research Training; Role; Rural; Structure; Students; Time; Training; Traumatic Brain Injury; Uganda; Universities; Work; aged; caregiving; clinical Diagnosis; community intervention; dementia care; disability-adjusted life years; early childhood; education research; health training; multiple chronic conditions; neuropathology; normal aging; programs; skills; social; therapy development; tool; undergraduate student

Abstract Dementia is the third leading cause of disability adjusted life years globally, affecting individuals, families, and communities, driving many households below the poverty line. Dementia is mainly diagnosed among persons aged 65 years or older, with Alzheimer’s Disease (AD) contributing 50–70% of the cases, the Despite availability of dementia diagnostic tools, 62% of cases of ADRD) worldwide are undiagnosed, while 91% of those that are diagnosed, are diagnosed very late. Early diagnosis prompts early evaluation and timely access to information, medical treatment, support for caregivers, and targeted community interventions. remaining contributed by other dementias. Alzheimer’s Disease and Related Dementias (AD/ In Africa, patients who present with dementia rarely receive proper care because the condition is regarded as part of normal ageing. While the true picture of AD in Uganda is not known, our previous work, under the D43TW010128 program, estimated the prevalence of dementia in rural south western Uganda at 20%. Although consensus guidelines on the assessment for AD/ADRD are clear, we found knowledge gaps in the assessment and management of AD/ADRD among primary healthcare providers in rural Uganda. We propose the “Alzheimer’s Disease and Related Dementias Health Professions Training Initiative (ARDHePTI)” to expand on the scope of the current Health-professions Education Partnership Initiative- Transforming Ugandan Institutions Training Against HIV/AIDS-R25TW011210, by including education and research in AD/ADRD while leveraging on the investment of the Mbarara Alzheimer’s and related Dementia Research Initiative D43TW010128-04S1 To train health professions (HP) undergraduate students in basic biomedical and clinical AD/ADRD, by providing the following training in AD/ADRD: (i) epidemiology and neuropathology (ii) biomarkers and clinical diagnosis, and (iii) treatment and caregiving to patients; b) To conduct practica on care models for AD/ADRD at facilities that care for the elderly with dementia in Uganda, gaining skills in dementia assessment and management in real life models of care for the elderly with AD/ADRD in Uganda; and c) To train health professions (HP) undergraduate students in research methodology to conduct mentored research in AD/ADRD in rural Uganda, using a hybrid of asynchronous (use of pre-recorded materials) and synchronous (in-person using the Structured Operational Research and Training IniTiative [SORT IT] approach). We will competitively select and provide HP students with skills in qualitative and quantitative research methodologies to enable assessment of the behavioral and social risk factors of AD/ADRD; linkage between pregnancy complications and development of AD; exposure to CNS infections during early childhood; the role of traumatic brain injury in the development of dementia; and multimorbidity chronic conditions. At the end of which, we will have preliminary data that will lead to the development of interventional studies in AD/ADRD in Uganda. . This will be achieved through the following Aims: a)

抽象的 痴呆症是全球残疾调整生命年的第三大原因，影响个人、家庭、 和社区，导致许多家庭陷入贫困线以下，痴呆症主要是在这些人群中诊断出来的。 65 岁或以上的人，阿尔茨海默病 (AD) 占病例的 50-70%， 尽管有痴呆症诊断工具，但 62% 的病例 ADRD）在全世界范围内都未被诊断出来，而其中 91% 早期诊断提示早期评估并及时获得治疗。 信息、医疗、对护理人员的支持以及有针对性的社区干预。 其余由其他痴呆症造成。 阿尔茨海默病和相关痴呆症 (AD/ 在非洲， 患有痴呆症的患者很少得到适当的护理，因为这种情况被视为是 虽然乌干达 AD 的真实情况尚不清楚，但我们之前的工作是在 D43TW010128 计划估计乌干达西南部农村地区痴呆症患病率为 20%。 尽管 AD/ADRD 评估的共识指南很明确，但我们发现在评估方面存在知识差距 乌干达农村初级卫生保健提供者的 AD/ADRD 评估和管理。 我们 提出“阿尔茨海默病和相关痴呆症卫生专业培训计划” (ARDHePTI)”扩大当前卫生专业教育伙伴关系倡议的范围- 转变乌干达艾滋病毒/艾滋病培训机构-R25TW011210，包括教育和 AD/ADRD 研究，同时利用 Mbarara 阿尔茨海默病和相关痴呆症的投资 研究计划 D43TW010128-04S1 培养健康 基础生物医学和临床 AD/ADRD 专业（HP）本科生，通过提供 AD/ADRD 培训后：(i) 流行病学和神经病理学 (ii) 生物标志物和临床诊断， (iii) 对患者进行治疗和护理； b) 在机构中开展 AD/ADRD 护理模式实践 照顾乌干达患有痴呆症的老年人，获得痴呆症评估和管理技能 乌干达 AD/ADRD 老年人的现实护理模式；以及 c) 培训卫生专业人员 (HP) 本科生学习研究方法，在农村开展 AD/ADRD 指导研究 乌干达，采用异步（使用预先录制的材料）和同步（亲自使用 结构化运筹学和培训计划 [SORT IT] 方法）我们将有竞争力。 选择 HP 学生并为其提供定性和定量研究方法的技能，以实现 评估妊娠并发症之间 AD/ADRD 的行为和社会危险因素； 和 AD 的发展；儿童早期接触中枢神经系统感染的作用； 痴呆症的发展；以及多种慢性疾病的发生。 初步数据将促进乌干达 AD/ADRD 干预研究的发展。 这将通过以下目标来实现：