Biostatistics, Epidemiology, and Research Design Core

生物统计学、流行病学和研究设计核心

• 批准号: 10281526
• 负责人: CHRISTOPHER H. SCHMID
• 金额: $ 34.92万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10281526
• 关键词: Address; Area; Bioinformatics; Biometry; Clinical; Clinical Research; Collaborations; Communities; Community Outreach; Community Participation; Conflict (Psychology); Consultations; Data; Data Analyses; Data Collection; Decision Making; Development; Diffusion; Discipline; Educational Models; Educational Technology; Educational process of instructing; Enrollment; Environment; Epidemiology; Foundations; Goals; Health; Health protection; Infrastructure; Institution; Investments; Lead; Learning; Link; Methods; Modality; Persons; Phase; Pilot Projects; Qualitative Research; Research; Research Design; Research Personnel; Research Support; Resources; Rhode Island; Schedule; Structure; Training; Training Support; Translational Research; Universities; Work; analytical method; analytical tool; biomedical informatics; community engagement; cyber infrastructure; design; epidemiology study; experience; faculty research; health data; improved; innovation; multidisciplinary; programs; satisfaction; tool; translational scientist; web portal; web site

ABSTRACT – BIOSTATISTICS, EPIDEMIOLOGY, AND RESEARCH DESIGN CORE The BERD Core has helped to transform clinical and translational research in Rhode Island during Phase I of Advance-CTR providing guidance in study design, data collection, data analysis, framing of results and drawing reasoned inferences. BERD has also provided training in research principles and a variety of essential tools. The result has been a markedly improved quality of research applications, increased diffusion of research support to young investigators, a high level of satisfaction and excitement in the research community, and a desire for even more support. In Phase II, the BERD Core will expand its support into new areas, using new modalities and reaching out to new audiences. We will work to connect the many isolated groups of analysts with whom we have connected who are embedded within Advance-CTR partners. Our goal is to evolve toward a sustainable infrastructure that meets the research needs of the entire state. By capitalizing on the existing resources of partner institutions, our efforts will help maximize the value of their existing investments as well as point to gaps in needs that can be filled through collaboration or expansion. Our centralized web portal already efficiently matches investigators to a highly qualified and diverse set of experts with long-term consultative experience and a reservoir of faculty research leaders skilled at teaching. We will expand consultative and training support, including adding a second Core Co-Lead, for designing and analyzing qualitative and mixed methods data. To increase enrollment and boost retention for training, flipped and asynchronous online modalities will be emphasized. The Advance-CTR website will be expanded to host educational pages. In addition to continuing support for the Pilot Project Program, Professional Development and Biomedical Informatics, Bioinformatics, and Cyberinfrastructure Enhancement (BIBCE) Core, we will collaborate with the new Community Engagement and Outreach Core to develop strategies to increase community participation in study design and data collection, design studies that properly address the health needs of the community and create results presentations that inform community decision making. To accomplish these goals, we propose the following Specific Aims. Specific Aim 1: Provide easily accessible, multidisciplinary collaborative support for quantitative and qualitative research design, analysis, interpretation, and dissemination that can work seamlessly with and within existing health research structures. Specific Aim 2: Provide training in study design, epidemiology, biostatistics and qualitative and mixed methods to clinical and translational researchers and research staff, delivered in a variety of formats, both synchronous and asynchronous (in-person and remote), using the latest educational methods and technologies. Specific Aim 3: Facilitate the development and widespread dissemination of innovative design and analytic methods and tools for clinical and translational research.

摘要 - 生物统计学，流行病学和研究设计核心 BERD核心已帮助改变了Rhode Island的临床和翻译研究。 Advance-CTR提供研究设计，数据收集，数据分析，结果框架和图形的指导 推理的推论。 Berd还提供了研究原理和各种基本工具的培训。 结果是研究应用的质量明显提高，研究的扩散增加 支持年轻的研究人员，研究界的高度满意和兴奋，以及 渴望更多的支持。 在第二阶段，BERD核心将使用新的方式将其支持扩展到新领域，并接触到 新受众。我们将努力联系我们与之联系的许多孤立的分析师组 被嵌入预先CTR合作伙伴中的人。我们的目标是发展朝着可持续的基础设施发展 满足整个州的研究需求。通过利用合作机构的现有资源，我们的 努力将有助于最大化其现有投资的价值，以及可以差距的差距 通过协作或扩展填充。我们的集中式网站已经有效地将调查人员与 具有长期咨询经验的高素质和多样化的专家，并且是教师的水库 熟练教学的研究领袖。我们将扩大咨询和培训支持，包括添加第二个 核心共同领导，用于设计和分析定性和混合方法数据。增加入学人数和 将强调培训，翻转和异步在线方式的促进保留率。 Advance-Ctr 网站将扩展到托管教育页面。除了继续支持飞行员项目 计划，专业发展和生物医学信息学，生物信息学和网络基础设施 增强（Bibce）核心，我们将与新的社区参与和外展核心合作 发展社区参与研究设计和数据收集的发展策略，设计研究 正确满足社区的健康需求并创建结果演讲，以告知社区 决策。为了实现这些目标，我们提出以下特定目标。 特定目标1：为定量和定性提供易于访问的多学科协作支持 研究设计，分析，解释和传播，可以与现有和内部无缝合作 卫生研究结构。 特定目的2：提供研究设计，流行病学，生物统计学以及定性和混合方法的培训 以各种格式交付的临床和翻译的研究人员和研究人员，都同步 以及使用最新的教育方法和技术的异步（面对面和远程）。 特定目的3：促进创新设计和分析的发展和宽度传播 临床和翻译研究的方法和工具。