Pilot Project Program (PPP)

试点项目计划（PPP）

• 批准号: 10324142
• 负责人: Andrew Robert Mayer
• 金额: $ 26.15万
• 依托单位: LOVELACE BIOMEDICAL RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-18 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10324142
• 关键词: Pilot; Project; Program; PPP

ABSTRACT Our Phase 1 (P-I)/Phase 2 (P-II) effort has enabled us to define the study of neuropsychiatric illness through the lens of systematic multimodal imaging as the thematic area of focus. We feel that we can be competitive at the national level for a center grant beyond the P-III given our current trajectory. During P-I/P-II we developed a strong state-of-the-art infrastructure and a strong research base composed of established faculty and successfully graduated junior PIs, some of whom now serve as core directors and mentors as part of our P-II and Phase 3 (P-III) COBRE programs (detailed in the various cores). Although the number of R01 grants won by local investigators meets the minimum requirement for consideration for a center grant, we still need to increase the number of R01s from MRN/UNM and other research institutions in NM in order to be competitive nationally. The proposed Pilot Project Program (PPP) is designed to maximize our ability to achieve this goal. The PPP will fund three categories of faculty members: (1) current P-II junior PIs and pilot project PIs who have existing pilot projects and need further support beyond their P-II projects; (2) junior faculty members with strong proposals who will be supported as new investigators during P-III; and (3) senior faculty members who wish to include neuroimaging as a new component of their pre-clinical or clinical research program to expand the scope of research. We will allocate a total of up to $250,000/year for our PPP, consisting of $125,000/year requested from the NIGMS and $125,000/year in institutional match funds. This funding will be used to support up to 5 projects at $50,000/project/year. To encourage productivity, each project will be funded for 1 year at a time, with the possibility for competitive renewal if meeting documented criteria and after evaluation by the steering committee (SC). The PPP will establish a training program for each successful PPP investigator on the use of the cores and will implement a mentoring program reminiscent of our P-II mentoring program, to provide mentorship to all 3 categories of funded faculty members. The selection of PPP-supported investigators and the oversight of our PPP will be carried out by the SC consisting of members of our P-II internal faculty development committee along with an administrative member and three core users. 2

抽象的 我们的第1阶段（P-I）/第2阶段（P-II）的工作使我们能够通过 系统的多模式成像的镜头是焦点的主题领域。我们认为我们可以竞争 鉴于我们目前的轨迹，p-iii以外的中心赠款的国家一级。在P-I/P-II期间，我们开发了 强大的最先进的基础设施和由已建立的教师组成的强大研究基础，并成功地毕业了初级PI，其中一些人现在是我们的P-II和阶段的一部分的核心主管和导师 3（p-III）毛线程序（在各种核心中详细介绍）。尽管当地赢得的R01赠款数量 调查人员符合中心赠款的最低要求，我们仍然需要增加 MRN/UNM和NM其他研究机构的R01数量，以便在全国范围内具有竞争力。这 拟议的试点项目计划（PPP）旨在最大程度地提高我们实现这一目标的能力。 PPP将资助 三类教职员工：（1）当前有现有试点项目的P-II初级PIS和试点PIS PIS，并且需要进一步的支持P-II项目； （2）有强有力的初级教职员工 在P-III期间，将作为新调查人员得到支持； （3）希望将神经影像纳入其前临床或临床研究计划的新组成部分，以扩大研究范围。我们 我们的PPP总共分配总计25万美元/年，由NIGMS要求的125,000美元/年组成 和$ 125,000/年的机构比赛资金。这笔资金将用于支持多达5个项目 $ 50,000/项目/年。为了鼓励生产力，每个项目一次将每次资助1年，如果符合已记录的标准和指导委员会（SC）评估后，则可能会更新竞争性。 PPP将为每个成功的PPP调查员建立一个有关使用核心的培训计划，并将 实施一个指导计划，让人联想到我们的P-II指导计划，以向所有3类资助的教职员工提供指导。选择PPP支持的研究人员和我们PPP的监督 SC将由我们的P-II内部教师发展委员会成员以及 管理成员和三个核心用户。 2