Core A: Administrative Core

核心A：行政核心

• 批准号: 10228047
• 负责人: ALAN D. D'ANDREA
• 金额: $ 14.97万
• 依托单位: DANA-FARBER CANCER INST
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-08-03 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10228047
• 关键词: Advocate; Cancer Burden; Cancer Center; Clinical; Collaborations; Communities; Development; Drops; Ensure; Feedback; Funding; Goals; Grant; Gynecologic Oncology; Institution; Leadership; Malignant neoplasm of ovary; Monitor; Patients; Performance; Recommendation; Research; Research Personnel; Resources; Role; Structure; Supervision; Time; Translational Research; Work; authority; base; career; experience; flexibility; improved; oncology program; programs; resistance mechanism; success

PROJECT SUMMARY Administrative Core The overarching goals of the Administrative Core of this Dana-Farber/Harvard Cancer Center (DF/HCC) Ovarian Cancer SPORE application are to provide leadership and administrative oversight of the overall grant, integration of the SPORE components as well as integration of the overall Ovarian Cancer SPORE within the Dana-Farber/Harvard Cancer Center (DF/HCC), and promote and engage activities that allow the success of the Ovarian Cancer SPORE Projects, Cores, the Developmental Research Program (DRP) and the Career Enhancement Program (CEP). Drs. Matulonis, D’Andrea, and Spriggs will work within the multi-PI/PD framework. The Leaders of this Ovarian Cancer SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will work directly with the DF/HCC SPORE Committee, the External Advisory Board (EAB), the Internal Advisory Board (IAB), and the Ovarian Cancer SPORE Advocate Board to obtain recommendations and feedback and implement them into the DF/HCC Ovarian Cancer SPORE components and the overall grant. The Overall Directors of this SPORE grant, Drs. Matulonis, D’Andrea, and Spriggs, will equally closely monitor projects throughout the entirety of the granting period and, in return, give constant and real time input; they will also have the authority to alter funding based upon project performance, and they will do this collaboratively. The structure of this SPORE grant will allow close supervision of all Projects and Cores and flexibility to allow project revision based on oversight feedback and whether underperforming projects should be dropped altogether or replaced. The SPORE PIs/PDs will ensure and facilitate interaction among the projects as well as access to SPORE resources such as Cores. The DRP and CEP will function as a critical pipeline of scientifically and clinically noteworthy projects and investigators that could be incorporated into the SPORE based on the advice of the advisory boards (EAB and IAB) and the DRP and CEP leadership; Drs. Matulonis and Spriggs will have direct oversight of the DRP and CEP.

项目概要 行政核心 达纳法伯/哈佛大学癌症中心 (DF/HCC) 行政核心的总体目标 卵巢癌 SPORE 申请旨在为整体拨款提供领导和行政监督， SPORE 组件的整合以及整个卵巢癌 SPORE 的整合 丹娜—法伯癌症研究所/哈佛大学癌症中心 (DF/HCC)，并促进和参与有助于成功开展的活动 卵巢癌 SPORE 项目、核心、发展研究计划 (DRP) 和职业 Matulonis、D’Andrea 和 Spriggs 博士将在多 PI/PD 内工作。 这项卵巢癌 SPORE 资助的领导者 Matulonis、D’Andrea 和 Spriggs 博士将 直接与 DF/HCC SPORE 委员会、外部顾问委员会 (EAB)、内部顾问委员会合作 委员会 (IAB) 和卵巢癌 SPORE 倡导委员会获取建议和反馈，并 将它们纳入 DF/HCC 卵巢癌 SPORE 组成部分和总体拨款中。 这项 SPORE 资助项目的负责人 Matulonis、D’Andrea 和 Spriggs 博士将同样密切关注项目。 在整个授予期间，作为回报，他们还将不断给予和实时投入； 有权根据项目绩效改变资助，并且他们将合作进行。 SPORE 赠款的结构将允许对所有项目和核心进行密切监督，并具有灵活性 根据监督反馈进行项目修订以及是否应放弃表现不佳的项目 SPORE PI/PD 将确保并促进项目之间以及项目之间的互动。 访问 SPORE 资源（例如核心）将充当关键的管道。 可以纳入 SPORE 的具有科学和临床意义的项目和研究人员 基于顾问委员会（EAB 和 IAB）以及 DRP 和 CEP 领导层的建议； Spriggs 将直接监督 DRP 和 CEP。